Ara
Toplam kayıt 14, listelenen: 11-14
Drug repositioning approach for the treatment of ankylosing spondylitıs
(Ankara University, 2022)
Objective: In this study, it was aimed to determine an FDA-approved molecule that inhibits the IL-17
receptor, which is an important target for the prevention of inflammation in Ankylosing Spondylitis (AS), using
the ...
Development of new cyclophilin d receptor inhibitors for the treatment of multiple sclerosis
(Ankara University, 2022)
Objective: In this study, it was aimed to carry out computational studies for the development of new molecules for the inhibition of the cyclophilin D (CypD) receptor, which causes the disability of mitochondrial function ...
Synthesis and molecular docking studies of some novel antimicrobial benzamides
(Academic Press Inc Elsevier Science, 2020)
Common use of classical antibiotics has caused to the growing emergence of many resistant strains of pathogenic bacteria. Therefore, we aimed to synthesize a number of N-(2-hydroxy-(4 or 5)-nitrophenyl)benzamide derivatives ...
Determination of novel SARS-CoV-2 inhibitors by combination of machine learning and molecular modeling methods
(Bentham Science, 2023)
Introduction: Within the scope of the project, this study aimed to find novel inhibitors by combining computational methods. In order to design inhibitors, it was aimed to produce molecules similar to the RdRp inhibitor ...