Yazar "RTEÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü" için TF, Cerrahi Tıp Bilimleri Bölümü Koleksiyonu listeleme
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Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
Çınar, Seda; Tümkaya, Levent; Mercantepe, Tolga; Saral, Sinan; Rakıcı, Sema; Yılmaz, Adnan; Topçu, Atilla; Şen, Ahmet; Karakaş, Sibel (Springer, 2021)Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ... -
Contribution of neutrophil activation in the differentiation of urine infection and contamination in pregnant women
Şahin, Kazım; Dilek, Aziz Ramazan; Güven, Emine Seda Güvendağ; Yazıcı, Zihni Açar (Karger, 2015)Background: Urinary tract infections are among the most common bacterial infections of humans. Urine culture is the gold standard for asymptomatic bacteriuria and pyuria is not always present in bacteriuria, nor is it ... -
Correlation of suicidal thoughts and toxoplasmosis in patients with depression
Bahçeci, İlkay; Bahçeci, Bülent; Şentürk, Şenol; Yıldız, İlknur Esen; Yazıcı, Zİhni Açar (Cureus Inc., 2021)Objective We investigated the correlation between serum anti-Toxplasma gondii IgG and suicidal thoughts in depressive patients. Methods Depressive patients with (n = 100) and without (n = 100) suicidal thoughts ... -
Cystic schwannoma of the right brachial plexus causing thoracic outlet syndrome
Sönmez, Osman Fikret; Tümkaya, Levent; Kanat, Ayhan; Demir, Zafer; Baş, Orhan (Ondokuz Mayıs University, 2012)A rare case of a schwannoma of the right brachial plexus presenting with a cystic lesion is presented here. A 36-year-old man was admitted to our department with numbness, pain and progressive, lingering paralysis in the ... -
The effect of dexmedetomidine on liver injury secondary to lower extremity ischemia-reperfusion in a diabetic rat model
Kartal, Seyfi; Şen, Ahmet; Tümkaya, Levent; Erdivanlı, Başar; Mercantepe, Tolga; Yılmaz, Adnan (Taylor & Francis Ltd., 2021)Introduction: In this study, we aimed to evaluate the hepatic protective effects of dexmedetomidine in the lower extremity ischemia-reperfusion model in diabetic rats biochemically and histopathologically. Methods: Rats ... -
Effect of infliximab on renal injury due to methotrexate in rat
Kırbaş, Aynur; Cüre, Medine Cumhur; Kalkan, Yıldıray; Cüre, Erkan; Tümkaya, Levent; Şahin, Osman Zikrullah; Yüce, Süleyman; Kızılkaya, Bayram; Pergel, Ahmet (Iranian Soc Nephrolgy, 2015)Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ... -
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells
Kalkan, Yıldıray; Bostan, Habib; Tümkaya, Levent; Tomak, Yakup; Bostan, Mehmet; Yılmaz, Adnan; Türüt, Hasan; Temiz, Ahmet; Yalçın, Alper; Turan, Alparslan (Springer Link, 2012)Purpose: Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of ... -
Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Altuner, Durdu; Yılmaz, Adnan; Erdivanlı, Başar; Bedir, Recep; Yalçın, Alper; Turan, Alparslan (Sage Publications Inc, 2015)Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ... -
The effects of mobile phone exposure on mast cells in rat dura mater
Tümkaya, Levent; Kalkan, Yıldıray; Gökçe, Fatih Mehmet; Erdivanlı, Başar; Yılmaz, Adnan; Bahçeci, İlkay; Yazıcı, Zihni Açar; Mercantepe, Tolga (Soc Chilena Anatomia, 2019)Mobile phone use has increased rapidly. the central nervous system has been shown to be adversely affected by its electromagnetic field (EMF) resulting in headache and sleep disturbances. How the cells make up the CNS and ... -
Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study
Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Yılmaz, Adnan (Springer, 2012)Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ... -
The efficacy of magnetic resonance imaging for the diagnosis of superior semicircular canal dehiscence
Çeliker, Fatma Beyazal; Özgür, Abdulkadir; Çeliker, Metin; Beyazal, Mehmet; Turan, Arzu; Terzi, Suat; İnecikli, Mehmet Fatih (Aves, 2018)OBJECTIVE: This study aimed to evaluate the efficacy of magnetic resonance imaging (MRI) for diagnosing superior semicircular canal dehiscence (SSCD). MATERIALS and METHODS: the radiological records of patients who were ... -
Hepatic effects of ketamine administration for 2 weeks in rats
Kalkan, Yıldıray; Tomak, Yakup; Altuner, Durdu; Tümkaya, Levent; Bostan, Habib; Yılmaz, Adnan; Ünal, D.; Kara, A.; Turan, A. (Sage Publishing, 2014)The aim of the present study was to investigate the long-term and high-dose application of ketamine on the liver by employing histologic and biochemical methods. A total of 30 male rats were randomly assigned to control ... -
The hepatoprotective potential of resveratrol in an experimental model of ruptured abdominal aortic aneurysm via oxidative stress and apoptosis
Bilen, Arzu; Mercantepe, Filiz; Tümkaya, Levent; Yılmaz, Adnan; Batçık, Şule (Wiley, 2021)The mortality rate in ruptured abdominal aortic aneurysms can today be reduced through cardiovascular surgery. However, ischemia and reperfusion-induced tissue damage develop due to aortic cross-clamping applied during ... -
Investigation of soft palate-uvula volume using magnetic resonance imaging in patients with obstructive sleep apnea
Çeliker, Fatma Beyazal; Çeliker, Metin; Terzi, Suat; Beyazal, Mehmet; Coşkun, Zerrin Özergin; Şahin, Ünal; Demirci, Münir; Dursun, Engin; Turan, Arzu (Derman Medical Publ, 2017)Aim: MRI-based sleep studies have revealed that airway movement disorders are associated with obstructive sleep apnea syndrome (OSAS). High-quality airway images are crucial for the accurate interpretation and planning of ... -
A novel model approach for esophageal burns in rats: a comparison of three methods
Kalkan, Yıldıray; Tümkaya, Levent; Akdoğan, Remzi Adnan; Yücel, Ahmet Fikret; Tomak, Yakup; Şehitoğlu, İbrahim; Pergel, Ahmet; Kurt, Aysel (Sage Publications Inc, 2015)Background: Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure. Materials and methods: We conducted ... -
The protective effects of whortleberry extract against cisplatin-induced ototoxicity in rats
Özdemir, Doğukan; Özgür, Abdulkadir; Kalkan, Yıldıray; Terzi, Suat; Tümkaya, Levent; Yılmaz, Adnan; Çeliker, Metin; Dursun, Engin (Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2019)Introduction: Cisplatin is one of the main chemotherapeutic agents used for the treatment of many types of cancer. However, ototoxicity, one of the most serious side effects of cisplatin, extract restricts its usage. ... -
Rize ilinde hemodiyaliz hastalarında HBsAg, Anti-HBs ve Anti-HCV seroprevalansı
Çopur, Ayşegül Çiçek; Şahin, Osman Zikrullah; Topaloğlu, Mustafa Kemal; Taşkaya, Ayşe Asena Kazancı; Yenilmez, İsmail Hakkı; Şahin, Kazım; Gündoğdu Ulusan, Deniz Zehra (2013)Amaç: Viral hepatitler hemodiyaliz ünitelerinde hem çalışan hem hastalar için önemli bir risk olmaya devam etmektedir. Enfeksiyon kontrol önlemlerinin ve aşılamanın düzenli yapıldığı diyaliz ünitelerinde hepatit B virus ... -
Secondary bacterial infection rates among patients with COVID-19
Bahçeci, İlkay; Yıldız, İlknur Esen; Duran, Ömer Faruk; Söztanacı, Umut Serkan; Harbawi, Zeynep Kırdı; Şenol, Feray F.; Demiral, Gökhan (Cureus Inc., 2022)Objective The aim of this study was to determine the factors and rates of secondary bacterial infections developed in patients after the diagnosis of COVID-19 and antimicrobial susceptibility to guide the empirical ... -
Total thiol can contribute to differentiating prostate cancer from BPH: Prostate Thiol Index as a new player
Arpa, Medeni; Şen, Bayram; Eren, Hüseyin; Uzun, Hakkı; Okcu, Oğuzhan; Erel, Özcan (Wiley, 2021)To assess the distinctiveness of serum native thiol (NT), total thiol (TT) and disulfide (SS) levels in PCa patients, we created a new parameter, prostate thiol index (PTI) [tPSA (TTxPVxAge) (-1/2)]. We determined the ... -
Variations of the superficial peroneal nerve and ıts terminal branches in the Turkish newborn fetuses
AMAÇ: Nervus peroneus superficialis (SPN) ve uç dallarının ayak ve bacaktaki topografik anatomisi hakkında daha detaylı bilgi vermek amacıyla Türkiye'deki yenidoğan fetuslar üzerinde bu çalışma gerçekleştirildi. YÖNTEM ve ...