Başlık için TF, Temel Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 566, listelenen: 531-550
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Synthesis and radical scavenging activity of new phenolic hydrazone/hydrazide derivatives: Experimental and theoretical studies
(Elsevier, 2021)Hydrazone and hydrazone-hydrazide-based compounds represent important classes of compounds that continue to attract increasing interest due to their diverse pharmacological actions. In the present study, a series of new ... -
Synthesis, characterization, theoretical studies and in vitro embriyotoxic, genotoxic and anticancer effects of novel phenyl(1,4,6-triphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl) methanone
(Taylor & Francis L.T.D., 2023)In this study, phenyl (1,4,6-triphenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methanone was obtained by using the Biginelli reaction method. The structure of this compound was analyzed using elemental analysis, IR, 1H, ... -
Syringaldehyde exerts neuroprotective effect on cerebral ischemia injury in rats through anti-oxidative and anti-apoptotic properties
(Shenyang Editorial Dept Neural Regeneration Res, 2014)There are few studies on the neuroprotective effects of syringaldehyde in a rat model of cerebral ischemia. the study aimed to elucidate the mechanisms underlying the neuroprotective effects of syringaldehyde on ischemic ... -
Taenıa ınfestatıon ın the appendıx: a case report
(Southeast Asian Ministers Educ Organization, 2013)Taenia saginata is a zoonotic cestode causing taeniasis. Taeniasis refers to the intestinal infection with the adult stage of this tapeworm. An association between teaniasis and acute appendicitis is uncommon. We present ... -
Tannic acid exhibits anti-inflammatory effects on formalin-induced paw edema model of inflammation in rats
(Sage Publications Ltd, 2019)The aim of the study was to determine the relationship between anti-inflammatory effects of the natural polyphenolic compound tannic acid (CAS number: 1401-55-4) and myeloperoxidase (MPO) enzyme activity in paw edema model. ... -
Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer
(Elsevier, 2023)Improving the chemotherapy sensitivity of bladder cancer is a current clinical challenge. It is critical to seek out effective combination therapies that include low doses of cisplatin due to its dose-limiting toxicity. ... -
Tea grape reduces abdominal aortic occlusion-induced lung injury
(Soc Brasil Cirurgia Cardiovasc, 2020)Introduction: Ischemia-associated mortality caused by aortic cross-clamps, as in ruptured abdominal aorta aneurysm surgeries, and reperfusion following their removal represent some of the main emergency conditions in ... -
Tear film osmolarity in patients with graves ophthalmopathy
(Tıp Araştırmaları Derneği, 2014)To investigate changes of tear osmolarity in patients with Graves ophthalmopathy (GO). Twenty-three patients with GO (GO group) and 25 healthy controls (control group) were enrolled in the study. GO patients were divided ... -
The therapeutic effect of thymoquinone on acoustic trauma-induced hearing loss in rats
(Springer, 2017)Thymoquinone has antioxidant properties. We hypothesized that thymoquinone may prevent or alleviate hearing loss induced by acoustic trauma. We aimed to study thymoquinone's effect on hearing function with distortion-product ... -
Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in vitro and in vivo models of Alzheimer's disease
(Wiley, 2021)Due to the complex nature of Alzheimer's disease (AD), it is important to investigate agents with multiple effects in the treatment of AD. Carvacrol possesses anti-acetylcholinesterase, anti-oxidant, and neuroprotective ... -
Three cases of fungemia caused by Blastoschizomyces capitatus
(Ankara Microbiology Soc, 2013)Blastoschizomyces capitatus is a rare fungal pathogen that may lead to severe and fatal systemic infections especially in immunosuppressive individuals. B.capitatus strains have also been reported as the cause of ... -
Three seasonal comprehensive evaluation process of Digitalis trojana Ivan's phenolics
(Elsevier Science Bv, 2016)Digitalis trojana Ivan, a member of Digitalis genus, has highly bioactive properties due to, efficient phenolics. These compounds have shown to convert into each other in a limited time. Seasonal fluctuations of this plant ... -
To determine LDL phenotypes using lipids, lipoproteins, apoproteins, and sdLDL through association rule mining
(Erciyes University Faculty of Medicine, 2023)Objective: The atherogenic lipoprotein phenotype is closely associated with the risk assessment of Coronary Artery Disease (CAD) and the monitoring of treatment processes. Particularly, high levels of small dense low-density ... -
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
(Wolters Kluwer Medknow Publications, 2014)Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ... -
Topiramate has protective effect on renal injury
(Comenius Univ, 2015)Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ... -
Topiramate reduces aortic cross-clamping-induced lung injury in male rats
(NLM (Medline), 2018)BACKGROUND: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) ... -
Total thiol can contribute to differentiating prostate cancer from BPH: Prostate Thiol Index as a new player
(Wiley, 2021)To assess the distinctiveness of serum native thiol (NT), total thiol (TT) and disulfide (SS) levels in PCa patients, we created a new parameter, prostate thiol index (PTI) [tPSA (TTxPVxAge) (-1/2)]. We determined the ... -
Toward changing of the pathophysiologic Basis of Acute Hydrocephalus after subarachnoid hemorrhage: a preliminary experimental study
(Elsevier Science Inc, 2013)BACKGROUND: Acute hydrocephalus (ventricular enlargement within 72 hours) is a common complication in patients with aneurysmal subarachnoid hemorrhage (SAH). Cerebrospinal fluid (CSF) secretion may be increased in the early ... -
Towards a comprehensive tobacco-cessation approach: A pilot-training using simulation based-learning among medical students in Türkiye
(2023)Dear Editor, Tobacco control (TC) is underpinned in two main strategies: preventing youth initiation and promoting tobacco cessation among users1 . Healthcare professionals (HCPs), and specially physicians, should lead ... -
Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters
(Elsevier, 2021)Background and objective: Breast cancers are the most common type of cancer and the most common cause of mortality in women worldwide. Different prognostic factors are the subject of research to differentiate the prognosis ...
