Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 564, listelenen: 41-60
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Investigation of a glioblastoma risk-associated SNP of the PTPRB Gene in familial glioblastoma
(Turkiye Klinikleri, 2023)Objective: To investigate the association of the single nucleotide polymorphism (SNP) rs2252784 in the protein tyrosine phos-phatase receptor type B (PTPRB) gene with familial glioblastoma multiforme (GBM). Material and ... -
Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
(Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
Synthesis and biological evaluation of novel benzylidene thiazolo pyrimidin-3(5H)-one derivatives
(Taylor & Francis Ltd., 2023)Starting compound 1 was synthesized according to reference. 1 Benzylidene thiazole pyrimidin-3(5H)-ones were synthesized reactions of 1 with bromoacetic acid and various aryl-aldehydes in the same vessel via one-step, ... -
Seroprevalence of toxoplasma, rubella and cytomegalovirus in women of fertility age in our region
(Galenos Publishing, 2023)Objective: Toxoplasma gondii (T. gondii), Rubella and Cytomegalovirus (CMV) infections can cause severe morbidity in the fetus when transmissed during pregnancy. In our study, it was aimed to examine the seropositivity ... -
Evaluation of serum semaphorin 3A and interleukin 6 levels in patients with pseudoexfoliation syndrome
(Springer, 2023)Purpose: To evaluate serum semaphorin 3A (Sema3A) and interleukin 6 (IL-6) levels in pseudoexfoliation syndrome (PXS) patients to determine whether these mediators play a role in the systemic manifestations of PXS. Methods: ... -
Diagnostic value of serum signal peptide-CUB-EGF-like domain- containing protein 1 levels in patients with acute appendicitis
(Assoc Medica Brasileira, 2023)OBJECTIVE: Acute appendicitis is one of the most common surgical causes of an acute abdomen among patients admitted to the emergency room due to abdominal pain. The clinical diagnosis of acute appendicitis is usually ... -
The effects of coenzyme Q10 (CoQ10) on Ionizing radiation- induced pancreatic β-cell injury
(AVES, 2023)Objective: This study investigated the antioxidant effect of coenzyme Q10 on ionizing radiation induced oxidative damage in pancreatic & beta;-cells. Methods: Twenty-four male rats were assigned to 4 groups. Group 1 ... -
Protective effect of vaccinium myrtillus extract on x-ray irradiation-induced retinal toxicity via enos and 8-ohdgexpression
(Karger, 2023)Every year, hundreds of thousands of cancer patients receive radiotherapy treatment. Oxidative stress is observed in healthy tissues due to irradiation exposure. The present study is the first to address the effects of ... -
The effects of carvacrol on transient receptor potential (TRP) channels in an animal model of parkinson's disease
(Springer, 2023)In this study, we aimed to investigate the effects of carvacrol (CA), a widely used phytochemical having anti-oxidant and neuroprotective effects, on transient receptor potential (TRP) channels in an animal model of ... -
Identification of the potential matrix protein of invertebrate iridescent virus 6 (IIV6)
(Elsevier, 2023)Invertebrate iridescent virus 6 (IIV6) is a nucleocytoplasmic virus with a similar to 212 kb linear dsDNA genome that encodes 215 putative open reading frames (ORFs). Proteomic analysis has revealed that the IIV6 virion ... -
Determination of the cytotoxicity and antibiofilm potential effect of equisetum arvense silver nanoparticles
(Springer, 2023)This study aimed to synthesize and characterize silver nanoparticles (AgNPs) by green synthesis from Equisetum arvense (Ea) extracts and to investigate their cytotoxicity, antibiofilm activity, and alpha-glucosidase enzyme ... -
Investigation of symptoms and lung functions in tea packaging factory employees
(Taylor & Francis Ltd., 2023)Inhalation of organic powders may lead to various diseases such as asthma-like syndrome and hypersensitivity pneumonia. The study aim to evaluate respiratory health effects by respiratory function measurements, respiratory ... -
A new practical method of estimating tumoral microenvironment parameters of possible prognostic significance in patients with invasive breast carcinoma: Combined microenvironment score
(Elsevier, 2023)Background and objective: In recent years, the tumor microenvironment has become increasingly recognized as an influential factor in breast cancer development and growth. The parameters that form the microenvironment are ... -
Targeting the anaphase-promoting complex/cyclosome (APC/C) enhanced antiproliferative and apoptotic response in bladder cancer
(Elsevier, 2023)Improving the chemotherapy sensitivity of bladder cancer is a current clinical challenge. It is critical to seek out effective combination therapies that include low doses of cisplatin due to its dose-limiting toxicity. ... -
The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas
(Elsevier, 2023)Background and objective: The prognostic importance of lymphoid cells in the tumor microenvironment and their effect on treatment response have been demonstrated in many cancer types. However, there are limited studies on ... -
Predicting response to neoadjuvant therapy with glucose transporter-1 in breast cancer
(Assoc Medica Brasileira, 2023)OBJECTIVE: Glucose transporter-1 is a marker involved in energy transport in cancer cells. It has been shown to be a poor prognostic factor in many cancer types, including breast cancer. However, there is no satisfactory ... -
Response to letter to the editor
(Elsevier, 2023)We would like to thank Dr. Altındağ for his interest in our publication (Prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast ... -
Radioprotective effects of alpha 2-adrenergic receptor agonist dexmedetomidine on X-ray irradiation-induced pancreatic islet cell damage
(Springer, 2023)Comprehensive epidemiological analyses conducted in the last 30 years have revealed a link between radiation and DM. We aimed to determine the effects of dexmedetomidine pretreatment on radiation-induced pancreatic islet ... -
Relationship between galectin-3 level and disease activity in ankylosing spondylitis patients
(Springer, 2023)Background and aimsAnkylosing spondylitis (AS) is a chronic inflammatory disease that chiefly affects the sacroiliac joints and the spine. Galectin-3, a chimera-type member of the galectin family, binds glycoconjugates ...
