Yazar "Cüre, Medine Cumhur" için listeleme
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Prognostic value of mean platelet volume and neutrophil to lymphocyte ratio in patients with Crimean-Congo Hemorrhagic Fever
Amaç: Kırım-Kongo Kanamalı Ateşi (KKHA) virüsü, Bunyaviridae ailesine üye Nairovirus olup insanlarda ciddi hastalığa neden olur. KKKA enfeksiyonunda pansitopeni, organ yetersizliği ve yaygın damar-içi pıhtılaşma ortaya ... -
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Tümkaya, Levent; Aydın, İbrahim; Kırbaş, Aynur; Efe, Hasan; Kurt, Aysel; Yüce, Süleyman (Wroclaw Medical Univ, 2016)Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ... -
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
Kurt, Aysel; Tümkaya, Levent; Yüce, Süleyman; Türüt, Hasan; Cüre, Medine Cumhur; Şehitoğlu, İbrahim; Kalkan, Yıldıray; Pusuroğlu, Gökhan; Cüre, Erkan (Mashhad Univ Med Sciences, 2016)Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ... -
Protective effect of infliximab against carbon tetrachloride-induced hepatotoxicity
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Özer, Ender; Cüre, Medine Cumhur; Yüce, Süleyman; Kalkan, Yıldıray; Cüre, Erkan (Begell House Inc, 2015)Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ... -
The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity
Aydın, İbrahim; Kalkan, Yıldıray; Özer, Ezgi Demir; Yücel, Ahmet Fikret; Pergel, Ahmet; Cüre, Erkan; Cüre, Medine Cumhur; Şahin, Dursun Ali (Verduci Publisher, 2014)OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ... -
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Kalkan, Yıldıray; Yılmaz, Arif; Yüce, Süleyman (Wolters Kluwer Medknow Publications, 2015)Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ... -
Protective effects of infliximab on lung injury induced by methotrexate
Kurt, Aysel; Tümkaya, Levent; Türüt, Hasan; Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Şehitoğlu, İbrahim; Acıpayam, Ahmet (Elsevier Espana Slu, 2015)Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ... -
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
Erkut, Adem; Cüre, Medine Cumhur; Kalkan, Yıldıray; Balık, Mehmet Sabri; Güvercin, Yılmaz; Yaprak, Esra; Yüce, Süleyman; Şehitoğlu, İbrahim; Cüre, Erkan (Verduci Publisher, 2016)OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ... -
The relationship between atherogenic index and carotid artery atherosclerosis in familial mediterranean fever: A pilot study
İçli, Abdullah; Cüre, Erkan; Uslu, Ali Uğur; Sakız, Davut; Cüre, Medine Cumhur; Özuçan, Miyase; Baykara, Rabia Aydoğan; Karakoyun, Ahmet; Balta, Şevket; Öztürk, Cengiz; Arslan, Şevket; Küçük, Adem (Sage Publications Inc, 2017)Familial Mediterranean fever (FMF) is a disease characterized by chronic inflammation. Atherogenic index of plasma (AIP) is a logarithmic value of the triglyceride to high-density lipoprotein cholesterol ratio and it is a ... -
Relationship between serum endocan levels and other predictors of endothelial dysfunction in obese women
Mercantepe, Filiz; Şahin, Serap Baydur; Cüre, Medine Cumhur; Karadağ, Zakir (Sage Publications, 2022)Endocan, or endothelial cell-specific molecule-1 (ESM-1), is a potential inflammatory marker implicated in endothelial dysfunction. The purpose of this study was to determine the correlation between serum endocan levels ... -
Relationship between site of myocardial infarction, left ventricular function and cytokine levels in patients undergoing coronary artery surgery
Kiriş, İlker; Kapan, Şahin; Narin, Cüneyt; Özaydın, Mehmet; Cüre, Medine Cumhur; Sütçü, Recep; Okutan, Hüseyin (Clinics Cardive Publ Pty Ltd, 2016)Background: the purpose of this study was to examine the relationship between left ventricular (LV) function, cytokine levels and site of myocardial infarction (MI) in patients undergoing coronary artery bypass grafting ... -
Relationship of osteoprotegerin to pulse wave velocity and carotid intima-media thickness in rheumatoid arthritis patients
Beyazal, Münevver Serdaroğlu; Erdoğan, Turan; Devrimsel, Gül; Türkyılmaz, Ayşegül Küçükali; Cüre, Medine Cumhur; Beyazal, Mehmet; Şahin, İsmail (Springer Heidelberg, 2016)Osteoprotegerin (OPG) is considered an important biomarker in cardiovascular (CV) disease. CV disease is the most common cause of mortality in patients with rheumatoid arthritis (RA), a consequence of accelerated ... -
Relationship of serum osteoprotegerin with arterial stiffness, preclinical atherosclerosis, and disease activity in patients with ankylosing spondylitis
Beyazal, Münevver Serdaroğlu; Erdoğan, Turan; Türkyılmaz, Ayşegül Küçükali; Devrimsel, Gül; Cüre, Medine Cumhur; Beyazal, Mehmet; Şahin, İsmail (Springer London Ltd, 2016)Patients with ankylosing spondylitis (AS) reportedly have a higher mortality and morbidity risk. Osteoprotegerin (OPG) was recently defined as an important cardiovascular (CV) marker in the general population. We aimed to ... -
Relationships between C-kit expression and mean platelet volume in benign, preneoplastic and neoplastic endometrium
Şehitoğlu, İbrahim; Bedir, Recep; Ural, Ülkü Mete; Güçer, Hasan; Yurdakul, Cüneyt; Cüre, Medine Cumhur; Cüre, Erkan; Yüce, Süleyman; Şahin, Figen Kır (Asian Pacific Organization for Cancer Prevention, 2015)Background: c-Kit is a proto-oncogene that encodes a tyrosine kinase receptor (CD117). Mean platelet volume (MPV) is a useful marker for demonstrating thrombocyte function. We aimed to investigate whether c-kit is expressed ... -
Requests for tumor marker tests in Turkey without indications and frequency of elevation in benign conditions
Cüre, Medine Cumhur; Cüre, Erkan; Kırbaş, Aynur; Yazıcı, Tarkan; Yüce, Süleyman (Asian Pacific Organization Cancer Prevention, 2012)Aims: To investigate the incidence of ordering tests for tumor markers which are used in cancer diagnosis, follow-up treatment and detection of recurrence, the rate of elevation in benign diseases and which clinics order ... -
Role of red cell distribution width in assessing response to treatment and prognosis in community?acquired pneumonia: A prospective study
Çınarka, Halit; Gümüş, Aziz; Özyurt, Songül; Karataş, Mevlüt; Gıakoup, Derya; Cüre, Medine Cumhur; Kayhan, Servet; Doğan, Deniz; Şahin, Ünal (2019)BACKGROUND AND AIM: Red blood cell distribution width (RDW) elevation occurs in various inflammatory/infectious conditions. RDW levels during monitoring have not been investigated prospectively in community?acquired pneumonia ... -
Serum fibronectin levels in acute and chronic viral hepatitis patients
Ertürk, Ayşe; Cüre, Erkan; Özkurt, Zülal; Parlak, Emine; Cüre, Medine Cumhur (Malaysian Journal of Medical Sciences, 2014)Background: The aim of this study was to investigate the serum fibronectin (FN) levels and liver enzyme activities in patients with acute hepatitis (A, B, C) and chronic viral hepatitis (B, C); determine whether the virus ... -
Serum levels of homocysteine, asymmetric dimethylarginine and nitric oxide in patients with Parkinson's disease
Kırbaş, Serkan; Kırbaş, Aynur; Tufekçi, Ahmet; Cüre, Medine Cumhur; Çakmak, Sevim; Yazıcı, Tarkan; Cüre, Erkan (Taylor & Francis Ltd, 2016)Objectives: Endothelial dysfunction has been implicated as a crucial event in the development of several neurodegenerative diseases. the aim of this study was to investigate the serum homocysteine, asymmetric dimethylarginine ... -
Serum levels of IL-17, IL-6, TNF-alpha and disease activity in patients with rheumatoid arthritis
Beyazal, Münevver Serdaroğlu; Devrimsel, Gül; Cüre, Medine Cumhur; Türkyılmaz, Ayeşegül Küçükali; Çapkın, Erhan; Karkucak, Murat (Georg Thieme Verlag Kg, 2017)Objective the aim of this study was to evaluate serum levels of interleukin (IL)-17, IL-6, and tumor necrosis factor alpha (TNF-alpha) in RA patients and to assess the correlation of these cytokines with clinical and ... -
Serum macrophage migration inhibitory factor levels in Hashimoto's thyroiditis; a case control study
Ayaz, Teslime; Şahin, Serap Baydur; Şahin, Osman Zikrullah; Cüre, Medine Cumhur; Sümer, Fatih; İlkkılıç, Kadir (BioMed Central Ltd., 2014)Objective: The cell-mediated immune process by CD4+ and CD8+ lymphocyte subsets of T-cells has a major role in the pathogenesis of Hashimoto's thyroiditis (HT). However, the exact mechanisms of initiation and progression ...