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Toplam kayıt 8947, listelenen: 7970-7989
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Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities
(Elsevier, 2009)4-Phenyl-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (3) was obtained in basic media via the formation of 2-isonicotinoyl-N-phenylhydrazinecarbothioamide (2), and converted to some alkylated derivatives (4a,b) and Mannich ... -
Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities
(Elsevier, 2009)4-Amino-2-[(5-arylamino-4,5-dihydro-1,3,4-thiadiazol-2-yl)methyl]-5-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones (3a-c) were obtained in acidic media via the formation of 2-[(4-amino-3-aryl-5-oxo-4,5-dihydro-1H-1 ... -
Synthesis of Some New Benzimidazole Derivatives Containing Chlorine and Investigation of Their Antioxidant and Anti-urease Activities
(2018)In this work, the synthesis of a 2-substituted benzimidazole compound containing chlorine (1) was carried out and then converted to the ester (2) and hydrazide (3) derivatives respectively. In the next steps, the hydrazide ... -
Synthesis of some new benzimidazole derivatives with their antioxidant activities
(Bentham Science Publ Ltd, 2015)In this paper, some benzimidazole derivatives containing salicyl, oxadiazole, thiosemicarbazide and 1, 2, 4-triazole moieties have been synthesized and screened their antioxidant activities screened. Antioxidant activities ... -
Synthesis of some new biheterocyclic triazole derivatives and evaluation of their antimicrobial activity
(TÜBİTAK, 2010)2-{3-(4-Substitutedbenzyl)-4-[2-(1H-indol-3-yl)ethyl]-5-oxo-4, 5-dihydro-1H-1,2,4-triazol-1-yl}-N' -(arylmethylene) acetohydrazides (5a-g), 4-amino-2-{3-(4-substitutedbenzyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1- yl}-N' ... -
Synthesis of Some New Ciprofloxacin Hybrids as Potential Antimicrobial Agents
(Wiley, 2017)A new series of ciprofloxacin hybrid compounds as new type of antimicrobial agents were synthesized and evaluated for antibacterial activity against Gram-positive and Gram-negative bacteria. -
Synthesis of some new hybride molecules containing several azole moieties and investigation of their biological activities
(Maik Nauka/Interperiodica/Springer, 2014)1,2,4-Triazole-3-one prepared from tryptamine was converted to the corresponding carbothioamides by several steps. Their treatment with ethyl bromoacetate or 4-chlorophenacyl bromide produced the corresponding 5-oxo-1,3- ... -
Synthesis of some new Methoxy Bridged Benzimidazolyl-Substituted phthalocyanines as potent inhibitors of urease
(Elsevier Science Sa, 2018)In this study, the novel peripherally 4-[(2-methyl-1H-benzimidazol-1-yl)methoxy] substituted Zn(II) (3) Cu(II) (4), Co(II) (5) phthalocyanines were prepared and their structures were characterized spectro-scopically. the ... -
Synthesis of some novel 1,2,4-triazol-3-one derivatives bearing the salicyl moiety and their anticonvulsant activities
(Wiley-V C H Verlag Gmbh, 2014)A series of new 1,2,4-triazole-3-one derivatives bearing the salicyl moiety were synthesized by using microwave irradiation, and their chemical structures were identified by IR, H-1 NMR, C-13 NMR, elemental analysis, and ... -
Synthesis of some novel heterocylic compounds derived from 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl]acetohydrazide and investigation of their lipase and alpha-glucosidase inhibition
(Taylor & Francis Ltd, 2015)In the present study, 2-[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl]acetohydrazide (1) was used as starting compound for the synthesis of 2-{[3-(4-chlorophenyl)-5-(4-methoxybenzyl)-4H-1,2,4-triazol-4-yl ... -
Synthesis of some novel pyrazoline and pyrazole derivatives as potential in vitro anti-xanthine oxidase and antioxidant activities
(Editura Acad Romane, 2018)2-Pyrazolines and 2-pyrazole, electron-rich nitrogen containing heterocyclic systems, play an important role in several biological and pharmacological activities. in this paper, we report the synthesis of novel ... -
Synthesis of some novel quinazolin-4(3H)-one hybrid molecules as potent urease inhibitors
(Wiley-V C H Verlag Gmbh, 2018)A new series of quinazolinone hybrid molecules containing coumarin, furan, 1,2,4-triazole and 1,2,4-thiadiazole rings was designed, synthesized, and screened for their urease inhibition activities. All newly synthesized ... -
Synthesis of taurine-Cu-3(PO4)(2) hybrid nanoflower and their peroxidase-mimic and antimicrobial properties
(Elsevier, 2022)Herein, we report the synthesis of taurine incorporated (sulfur containing organic molecule derived from methionine and cysteine) hybrid nanoflowers (thNFs) with an intrinsic peroxidase-mimic and antimicrobial activities ... -
Synthesis of unsymmetrical 3,5-disubstituted 1,2,4-triazole derivatives with their pKa values
(Chiminform Data S A, 2014)Acylhydrazones (2a-b) were synthesized by the condensation of iminoester hydrochlorides (1a-b) with benzhydrazide. the treatment of acylhydrazones With hydrazine hydrate afforded 4-amino-4H-1,2,4-triazoles. (3a-b). ... -
Synthesis of water-soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity
(Wiley, 2021)In this study, water-soluble BODIPY dyes (BDPY-4, BDPY-5) bearing dimethylamino and diethylamino groups were synthesized for the first time. The DNA interaction and nuclease effect of two water-soluble BODIPY dyes were ... -
Synthesis, aggregation and spectroscopic studies of novel water soluble metal free, zinc, copper and magnesium phthalocyanines and investigation of their anti-bacterial properties
(Pergamon-Elsevier Science Ltd, 2014)In this study, novel phthalonitrile derivative (3) was synthesized by the reaction between 4-nitrophthalonitrile (2) and a triazole derivative (1) containing pyridine moiety. Crystal structure of compound (3) was characterized ... -
Synthesis, alpha-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives
(Academic Press Inc Elsevier Science, 2020)In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their alpha-glucosidase inhibitory potential. All molecules showed a considerable ... -
Synthesis, and prediction of molecular properties and antimicrobial activity of some acylhydrazones derived from N-(arylsulfonyl)methionine
(Scientific Technical Research Council Turkey-Tubitak, 2016)A series of 38 new acylhydrazones [3-40], derived from (2S)-4-(methylsulfanyl)-2-[[(4-methylphenyl)sulfonyl] amino]butanoic acid hydrazide [2], were synthesized and evaluated for their anti-HIV and antimicrobial activity ... -
Synthesis, and prediction of molecular properties and antimicrobial activity ofsome acylhydrazones derived fromN-(arylsulfonyl)methionine
(2016)A series of 38 new acylhydrazones [3{40], derived from (2S)-4-(methylsulfanyl)-2-[[(4-methylphenyl)sulfonyl]amino]butanoic acid hydrazide [2], were synthesized and evaluated for their anti-HIV and antimicrobial activity ... -
Synthesis, antibacterial and antioxidant activities of new 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2013)New 1-alkyl-4-(1-alkyl-4-oxo-1,4-dihydroquinolin-2-yl)pyridinium bromides (3a k) were synthesized from 1,4'-diazaflavone [2-pyridin-4-ylquinolin-4(1H)-one] and evaluated for antibacterial and antioxidant activities. A rapid ...
