Yazar "Atak, Mehtap" için listeleme
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Association between plasma monocyte chemoattractant protein-1 levels and the extent of atherosclerotic peripheral artery disease
Şatıroğlu, Ömer; Uydu, Hüseyin Avni; Demir, Adem; Bostan, Mehmet; Atak, Mehtap; Bozkurt, Engin (2011)Peripheral artery disease occurs at advanced ages and accounts for substantial cardiovascular morbidity and mortality. Monocyte chemoattractant protein-1 (MCP-1), a member of the cysteine-cysteine family of chemokines, is ... -
The association of Sort1 expression with LDL subfraction and inflammation in patients with coronary artery disease
Atak, Mehtap; Sevim Nalkıran, Hatice; Bostan, Mehmet; Uydu, Huseyin Avni (Taylor & Francis Ltd., 2023)Background: Controversial effect of sortilin on lipoprotein metabolism in the development of atherosclerosis reveals the need for more extensive research Objectives: The aim of this study was to investigate the association ... -
Celastrol restricts experimental periodontitis related alveolar bone loss by suppressing inflammatory cytokine response
Altın, Ahmet; Korkmaz, Meltem Zihni; Atak, Mehtap; Mercantepe, Tolga; Yılmaz, Hülya Kılıç (China Medical University, 2023)Introduction: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. The host defense mechanisms are responsible for inflamatuar and destructive ... -
Cholesterol forms and traditional lipid profile for projection of atherogenic dyslipidemia: lipoprotein subfractions and erythrocyte membrane cholesterol
Uydu, Hüseyin Avni; Bostan, Mehmet; Atak, Mehtap; Yılmaz, Adnan; Demir, Adem; Akcan, Buket; Sümer, Fatih; Baltaş, Nimet; Karadağ, Zakir; Uğurlu, Yavuz; Örem, Asım (Springer, 2014)Atherogenic dyslipidemia characterized by abnormal changes in plasma lipid profile such as low high-density lipoprotein (HDL) and increased triglyceride (TG) levels is strongly associated with atherosclerotic diseases. We ... -
Comparison of inflammatory biomarkers for detection of coronary stenosis in patients with stable coronary artery disease
Uydu, Hüseyin Avni; Bostan, Mehmet; Yılmaz, A.; Demir, Adem; Atak, Mehtap; Şaturoğlu, Ömer; Temiz, A.; Çiçek, Yağız Anıl; Erdoğan, Turan; Çetin, Mustafa; Canga, Aranzazu Gonzalez (Verduci Publisher, 2013)BACKGROUND: the objective of the current study was to evaluate the role of various inflammatory biomarkers in detection of coronary stenosis in patients with stable coronary artery disease (CAD) and healthy people. METHODS: ... -
Diagnostic value of serum thiobarbituric acid reactive substances levels in pediatric acute appendicitis
Altuntaş, Gürkan; Altuntaş, Mehmet; Atak, Mehtap (Sakarya Üniversitesi, 2024)Purpose: This study aims to show the diagnostic value of Serum Thiobarbituric Acid Reactive Substances in pediatric appendicitis. Method: Eighty-five pediatric patients hospitalized in the pediatric surgery ward with acute ... -
Distribution of coronary artery risk factors: a regional analysis
Bostan, Mehmet; Şatıroğlu, Ömer; Uydu, Hüseyin Avni; Çiçek, Yüksel; Çanğa, Aytun; Karadağ, Zakir; Temiz, Ahmet; Uǧurlu, Yavuz; Atak, Mehtap; Bozkurt, Engin (2011)Amaç: Bu çalışmadaki amacımız, Rize ili ve civarında koroner arter risk faktörlerinin sıklık ve dağılımını incelemektir. Yöntem ve gereç: Bu gözlemsel çalışmaya, 452 hasta (333 erkek, 119 kadın) alındı. Hastaların demografi ... -
Effect of white tea consumption on serum leptin, TNF-alpha and body weight in menopausal model rats
Saral, Sinan; Yıldırım, Murat; Atak, Mehtap; Dokumacıoğlu, Eda (Karger, 2018)[No abstract available] -
Effect of white tea consumption on serum leptin, TNF-alpha and UCP1 gene expression in ovariectomized rats
Saral, Sinan; Saydam, Faruk; Dokumacıoğlu, Eda; Atak, Mehtap; Tümkaya, Levent; Uydu, Hüseyin Avni (John Libbey Eurotext Ltd., 2021)Background: Obesity and dyslipidemia due to estrogen deficiency are among the important health problems in menopausal women. Increasing evidence reports the anti-obesity and anti-hyperlipidemic properties of tea polyphenols. ... -
The effect of white tea on serum TNF-alpha/NF-kappa B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats
Saral, Sinan; Dokumacıoğlu, Eda; Mercantepe, Tolga; Atak, Mehtap; Çınar, Seda; Saral, Özlem; Yıldız, Lamiye; İskender, Hatice; Tümkaya, Levent (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)Objective: Nephrotoxicity is the most important side effect of the antineoplastic drug cisplatin, thereby restricting its use. the aim of this study was to investigate the protective effects of white tea infusions(WT) ... -
The effectiveness of electro-acupuncture in ovarian ischemia reperfusion injury
Keskin, Seda; Keskin, Deha Denizhan; Değermenci, Muhammet; Hancı, Hatice; Karabekir, Nüket Göçmen; Atak, Mehtap; Baş, Orhan (Cognizant Communication Corp, 2021)Electro-acupuncture is widely used in gynecology. Adnexal torsion is an important threat to ovarian reserves in women of reproductive age. This is the first study to investigate whether electro-acupuncture is beneficial ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
Topçu, Atilla; Öztürk, Aykut; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
Deniz, Esra; Topçu, Atilla; Öztürk, Aykut; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
The effects of white tea (Camellia Sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis
Çakıroğlu, Şenay; Mercantepe, Tolga; Tümkaya, Levent; Uydu, Hüseyin Avni; Topçu, Atilla; Atak, Mehtap (2023)Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, ... -
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
Topçu, Atilla; Balık, Gülşah; Atak, Mehtap; Mercantepe, Tolga; Uydu, Hüseyin Avni; Tümkaya, Levent (Elsevier, 2019)Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ... -
Investigation of the effects of white tea on liver fibrosis: An experimental animal model
Yılmaz, Hülya Kılıç; Türker, Merve; Kutlu, Eda Yılmaz; Mercantepe, Tolga; Pınarbaş, Esra; Tümkaya, Levent; Atak, Mehtap (Wiley, 2024)Liver fibrosis is a common, progressive disease that affects millions of patients worldwide. In this study, it was aimed at investigating the effect of white tea on liver fibrosis in an in-vivo environment by creating an ... -
Kaempferol reduces pyroptosis in acute lung injury by decreasing ADAM10 activity through the NLRP3/GSDMD pathway
Yiğit, Ertuğrul; Hüner Yiğit, Merve; Atak, Mehtap; Topal, Zehra Suzan; Karabulut, Soner; Yıldız, Gökhan; Değer, Orhan (Elsevier, 2024)Sepsis-associated acute lung injury (SA-ALI) is a significant problem in intensive care units worldwide, and no specific treatment is currently available. Therefore, it is crucial to identify new potential therapeutic ... -
Long-term protective effects of lamotrigine in a rat ovarian ischemia-reperfusion model
Aktepe, Rıza; Üçüncü, Yılmaz; Tümkaya, Levent; Mercantepe, Tolga; Topçu, Atilla; Uydu, Hüseyin Avni; Atak, Mehtap (Elsevier, 2024)Ovarium torsion is a gynecological emergency that is common in women of reproductive age and requires early diagnosis and intervention. In this study, we aimed to investigate the long-term anatomical, histological and ... -
The nephroprotective effect of amifostine in a cecal ligation-induced sepsis model in terms of oxidative stress and inflammation
Batçık, Şule; Tümkaya, Levent; Mercantepe, Tolga; Atak, Mehtap; Topçu, Atilla; Uydu, Hüseyin Avni; Mercantepe, F. (Verduci Editore, 2022)OBJECTIVE: Sepsis is responsible for more than 5 million deaths worldwide every year. The purpose of this study was to use amifostine to reduce acute kidney injury developing as a result of sepsis. MATERIALS AND METHODS: ...
