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HSP inhibitor sensitize resistant MCF-7 cells to doxorubicin through suppressing HSP90AB4P pseudogene and HSPB1 expression
Coşkun, Kübra Açıkalın; Tutar, Lütfi; Abay, Elif Cansu; Gülüm, Levent; Çelik, Ayşe Büşranur; Gümüş, Mehmet; Koca, İrfan; Tutar, Yusuf (Bentham Science Publishers, 2025)Introduction: Doxorubicin, a first-line chemotherapeutic agent, often faces resistance in breast cancer subtypes, leading to treatment failure. HSPs (Heat shock proteins), especially HSP90, and their pseudogenes like ...