Browsing by Author "Mentese, Emre"
Now showing items 1-20 of 38
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Design, molecular docking and synthesis of novel 5,6-dichloro-2-methyl-1H-benzimidazole derivatives as potential urease enzyme inhibitors
Mentese, Emre; Emirik, Mustafa; Sokmen, Bahar Bilgin (Academic Press Inc Elsevier Science, 2019)A novel series of 5,6-dichloro-2-methyl-1H-benzimidazole derivatives was synthesized and then screened for their urease inhibitory activity. All compounds showed more potent inhibitory activity in the range of IC50= 0.0294 ... -
Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents
Kahveci, Bahittin; Yilmaz, Fatih; Mentese, Emre; Ulker, Serdar (Wiley-V C H Verlag Gmbh, 2017)The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ... -
Design, synthesis, and characterization of some new benzimidazole derivatives and biological evaluation
Bektas, Hakan; Sokmen, Bahar B.; Aydin, Sinem; Mentese, Emre; Bektas, Adile; Dilekci, Gamze (Wiley, 2020)A new series of benzimidazole derivatives (1-15) containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and thiazolidinon rings have been synthesized. All new synthesized benzimidazole compounds were confirmed by ... -
Efficient Synthesis of 5-(Substituted)benzyl-2,4-Dihydro-3H-1,2,4-Triazol-3-Ones Using Microwave Irradiation
Kahveci, Bahittin; Mentese, Emre; Ozil, Musa; Bekircan, Olcay (Chem Soc Pakistan, 2013)A growing body of literature has shown the effectiveness of using microwave irradiation in chemical reactions. the aim of this study is to demonstrate a rapid and highly efficient synthesis of some new 5-aryl-2,4-dihydro ... -
Electrochemistry of Novel Phthalocyanines Bearing 1,2,4 Triazole Groups
Akyuz, Duygu; Demirbas, Umit; Akcay, Hakki Turker; Mentese, Emre; Koca, Atif; Kantekin, Halit (Wiley-V C H Verlag Gmbh, 2020)The phthalonitrile (3) and triazole substituted metallo phthalocyanines (MPc) (4-7) were prepared. the novel compounds were characterized with spectroscopic data. Electrochemical analyses of metallophthalocyanines (4-7) ... -
Microwave Assisted Synthesis of Cournarins: A Review From 2007 to 2018
Kahveci, Bahittin; Mentese, Emre (Bentham Science Publ Ltd, 2018)Background: Microwave heating has been shown to be an invaluable technology for medicinal chemistry and drug discovery applications. Recently, it has been used for heterocyclic synthesis increasingly. This review article ... -
Microwave-Assisted Synthesis of Benzimidazoles and Their Derivatives From 1994 to 2016-A Review
Kahveci, Bahittin; Mentese, Emre (Bentham Science Publ Ltd, 2017)Background: the use of microwave irradiation is an important development for the synthesis of benzimidazoles in the 21st century, and in recent years, microwave-assisted heterocyclic synthesis has gained significant attention ... -
Mononuclear Cu(II) complex of an oxime ligand derived from N-Heterocyclic hydrazide: Synthesis, spectroscopy, electrochemistry, DFT calculations and catecholase activity
Zengin, Ali; Karaoglu, Kaan; Emirik, Mustafa; Mentese, Emre; Serbest, Kerim (Elsevier Science Bv, 2019)A new oxime derivative N-heterocyclic hydrazide ligand, N'-[(1E,2E)-2-(hydroxyimino)-1-methylpropylidene]-2-[(4-methyl-5-phenyl-4H-1,2,4-triazol-3-1)thio] acetohydrazide (1) and its mono-nuclear copper(II) complex (1a) ... -
A New Fluorescent "Turn-Off" Coumarin-Based Chemosensor: Synthesis, Structure and Cu-Selective Fluorescent Sensing in Water Samples
Karaoglu, Kaan; Yilmaz, Fatih; Mentese, Emre (Springer/Plenum Publishers, 2017)We report the synthesis and characterization two coumarin-based fluorescence probes, N'-{[7-(diethylamino)-2-oxo-2H-chromen-3-yl]carbonyl}pyridine-3-carbohydrazide (3) and N'-benzoyl-7-(diethylamino)-2-oxo-2H-chromene-3- ... -
NEW PYRIDINE DERIVATIVES AS ANTIUREASE INHIBITORS: SYNTHESIS AND THEIR EVALUATION FOR ANTIMICROBIAL ACTIVITIES
Bektas, Hakan; Albay, Canan; Mentese, Emre; Demirbas, Neslihan (Editura Acad Romane, 2017)6-Morpholin-4-ylpyridin-3-amine (3) gathered starting from morpholine by two steps was converted into the corresponding arylidenehydrazides through the reaction with several aromatic aldehydes. the treatment of compound 3 ... -
Novel 1,2,4-triazole substituted metallo-phthalocyanines: Synthesis, characterization and investigation of electrochemical and spectroelectrochemical properties
Demirbas, Umit; Akyuz, Duygu; Akcay, Hakki Turker; Koca, Atif; Mentese, Emre; Kantekin, Halit (Elsevier Science Bv, 2018)The phthalonitrile compound (3) and peripherally tetra substituted zinc(II) (4), nickel (II) (5), iron (II) (6), cobalt (II) (7) and copper (II) (8) phthalocyanines were synthesized for the first time in this study. the ... -
Novel phthalocyanines bearing 1,2,4 triazole substituents: Synthesis, characterization, photophysical and photochemical properties
Demirbas, Umit; Ozcifci, Zehra; Akcay, Hakki Turker; Mentese, Emre (Pergamon-Elsevier Science Ltd, 2020)4-(4,5-Diphenyl-4H-1,2,4-triazol-3-ylthio)phthalonitrile ( 3) and its non-peripherally tetra substituted zinc(II) phthalocyanine (4) and magnesium(II) phthalocyanine (5) derivatives were prepared. the novel compounds 3-5 ... -
Novel triazole substituted phthalocyanines showing high singlet oxygen quantum yields
Demirbas, Umit; Bayrak, Riza; Dilber, Gulsev; Mentese, Emre; Akcay, Hakki Turker (Elsevier, 2019)In this study, novel triazole peripherally substituted phthalocyanine zinc(II) complexes 3(a-d) were synthesized from four different phthalonitrile derivative and characterized by FT-IR NMR, MALDI-TOF, UV-Vis methods. ... -
STUDY OF ANTIOXIDANT, ANTIMICROBIAL AND ANTI-XANTHINE OXIDASE ACTIVITIES OF SOME 5,6-DIMETHYL-2-(SUBSTITUTED)-1H-BENZIMIDAZOLES AND THEIR ACYLHYDRAZIDE DERIVATIVES
Baltas, Nimet; Beris, Fatih Saban; Mentese, Emre (Raman Publ, 2017)In this study, a series of 5,6-dimethy1-2-(4-fluoro/chloro/bromo/methyl/nitrobenzy1)-1Hbenzimidazoles were screened for their bovine milk xanthine oxidase (XO) inhibition, antioxidant and antimicrobial activities. Compounds ... -
Synthesis and anticancer activities of some new coumarin derivatives including the triazole ring and their in silico molecular docking studies
Mentese, Emre; Guner, Adem; Polatli, Elifsu; Emirik, Mustafa; Bektas, Hakan; Kahveci, Bahittin (Wiley-V C H Verlag Gmbh, 2020)The synthesis, docking study, and investigation of the anticancer activities of some coumarin derivatives containing the triazole ring are reported in this study. the newly synthesized compounds were screened for their in ... -
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEW TRIAZOLE BRIDGED BENZIMIDAZOLE SUBSTITUTED PHTHALONITRILE AND PHTHALOCYANINES
Kantar, Gunay Kaya; Mentese, Emre; Beris, Fatih Saban; Sasmaz, Selami; Kahveci, Bahittin (Editura Acad Romane, 2018)In this study, some new phthalonitriles and metallophthalocyanines (Zn, Ni, Co, and Cu) containing triazole bridged benzimidazole moieties were synthesized starting from 2-(3-methylbenzyl)-1H-benzimidazole Newly synthesized ... -
Synthesis and Antioxidant Evaluation of Some Novel Benzimidazole Derivatives Containing a Triazole Nucleus
Yilmaz, Fatih; Mentese, Emre; Baltas, Nimet (Bentham Science Publ Ltd, 2017)Various benzimidazole compounds containing a triazole nucleus were synthesized and screened for their antioxidant activies. the structures of newly synthesized compounds were characterized by H-1 NMR, C-13 NMR and elemental ... -
Synthesis and antioxidant, antiurease and anti-xanthine oxidase activities of some new benzimidazoles bearing triazole, oxadiazole, thiadiazole and imin function
Karaali, Nesrin; Baltas, Nimet; Mentese, Emre (Natl Inst Science Communication & Information Resources-Niscair, 2018)In this study, a series of new 2-(4-nitrobenzyl)-1H-benzimidazole derivatives bearing thiosemicarbazide, triazole, oxadiazole and thiadiazole moieties at the 1st position of benzimidazole ring have been synthesized and ... -
Synthesis and Biological Evaluation of Some Succinimide Hybrid Molecules
Yilmaz, Fatih; Mentese, Emre; Baltas, Nimet (Maik Nauka/Interperiodica/Springer, 2019)In this study, a new series of succinimide hybrid molecules containing isothiocyanate, coumarin, isatin, and furan moieties was synthesized and screened for alpha-glucosidase and antioxidant activities. Preliminary results ... -
Synthesis and characterisation of some coumarin-1,2,4-triazol-3-thioether hybrid molecules
Yilmaz, Fatih; Mentese, Emre (Science Reviews 2000 Ltd, 2017)A new series of N'-{[(4-methyl/phenyl-5-phenyl-4H-1,2,4-triazol-3-yl) thio] acetyl}-2-oxo-2H-chromene-3-carbohydrazides was synthesised via the reaction of 2-[(4-methyl/phenyl-5-phenyl-4H-1,2,4-triazol-3-yl) thio] ...
