Browsing by Author "Süleyman, Halis"
Now showing items 1-20 of 30
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Benefits of the antioxidant and anti-inflammatory activity of etoricoxib in the prevention of ovarian ischemia/reperfusion injury induced experimentally in rats
Yapca, Ömer Erkan; Turan, Mehmet İbrahim; Yılmaz, İsmayil; Salman, Süleyman; Gülaboğlu, Mine; Süleyman, Halis (Wiley-Blackwell, 2014)Aim This study is a biochemical investigation of the effect of etoricoxib, a selective cyclooxygenase (COX)-2 inhibitor, on ischemia/reperfusion (I/R) injury experimentally induced in rat ovaries. Methods Experimental ... -
Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes
Yapca, Ömer Erkan; Turan, Mehmet İbrahim; Börekçi, Bünyamin; Akçay, Fatih; Süleyman, Halis (Mashhad Univ Med Sciences, 2014)Objective(s): This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/ reperfusion (I/ R) injury in diabetic rats and evaluated oxidant and antioxidant marker ... -
Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation
Üçüncü, Yılmaz; Çelik, Nuray; Öztürk, Cengiz; Türkoğlu, Murat; Çetin, Nihal; Koçkara, Nizamettin; Şener, Ebru; Dündar, Cihat; Arslan, Aynur; Doğan, Hasan; Kurt, Nezahat; Süleyman, Halis (Pergamon-Elsevier Science Ltd, 2015)Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain ... -
A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue
Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ... -
A comparative investigation of the nephrotoxic effects of various antihypertensive drugs in rats: biochemical and histopathological analysis
Malkoç, İsmail; Altunkaynak, Konca; Turan, Mehmet İbrahim; Gürsan, Nesrin; Hacımüftüoğlu, Ahmet; Akçay, Fatih; Üçüncü, Yılmaz; Süleyman, Halis (Carbone Editore, 2014)Aims: Hypertension is known to cause potentially fatal kidney damage. However, it is unclear whether long-term use of antihypertensive drugs establishes any toxic effect on the kidney. This study investigate whether ... -
Comparative review of biochemistry and cell anatomy of the hepatic tissue in rats administered some anti hypertensive drug for a long time
Malkoç, İsmail; Çetin, Nihal; Altuner, Durdu; Hacımüftüoğlu, Ahmet; Gürsan, Nesrin; Bakan, Ebubekir; Akçay, Fatih; Süleyman, Halis (2012)The adverse biochemical and structural effects of antihypertensive drugs over a long period (clonidine, methyldopa, rilmenidine, amlodipine, ramipril) on hepatic tissue has been examined in this study. The results are ... -
Damage induced by paracetamol compared with N-acetylcysteine
Kısaoğlu, Abdullah; Özoğul, Bünyamin; Turan, Mehmet İbrahim; Yılmaz, İsmail; Demiryılmaz, İsmail; Atamanalp, Sabri Selçuk; Bakan, Ebubekir; Süleyman, Halis (Lippincott Williams & Wilkins, 2014)Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol. Methods: Rats for this experiment were divided into the following groups: ... -
Effect of ethyl acetate extract of usnea longissima on esophagogastric adenocarcinoma in rats
Mammadov, Renad; Süleyman, Bahadır; Altuner, Durdu; Demirci, Elif; Çetin, Nihal; Yılmaz, Adnan; Baykal, Hüseyin; Alpcan, Hilal; Turumtay, Emine Akyüz; Süleyman, Halis (Acta Cirurgica Brasileira, 2019)Purpose: To investigate the effects of the EtOAc extract of U. longissima which is uninvestigated previously on esophagogastric cancer induced in rats with N-methyl-N-nitro-N-nitrosoguanidin (MNNG). Methods: the anticancer ... -
The effect of hippophae rhamnoides extract on oxidative damage on rat's gastric tissue depending on Co-implementation of methotrexate and indomethacin
Yılmaz, İsmayıl; Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Üçüncü, Yılmaz; Altuner, Durdu; Kurt, Nezahat; Kunak, Semih C.; Kısaoğlu, Abdullah; Özoğul, Bünyamin; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2014)The effect of Hippophae rhamnoides (HR) extract on oxidative damage on rat's gastric tissue depending on co-implementation of methotrexate (MTX) and indomethacin (IND) was investigated biochemically and histopathologically. ... -
Effect of Usnea longissima ethyl acetate extract on acute oxidative and inflammatory lung damage from Staphylococcus aureus infection in rats
Dabanlıoğlu, Bülent; Süleyman, Bahadır; Mammadov, Renad; Yavuzer, Bülent; Akyüz, Sümeyey; Akkaş, Önder; Mokhtare, Behzad; Turumtay, Emine Akyüz; Altuner, Durdu; Çoban, Taha Abdulkadir; Süleyman, Halis (University of South Bohemia in Ceske Budejovice Faculty of Health and Social Sciences, 2023)The role of oxidants and proinflammatory cytokines in the pathogenesis of pneumonia caused by Staphylococcus aureus (S. aureus) has been demonstrated. The present study aims to investigate the protective effect of ethyl ... -
The effect of usnea longissima extract on lung cancer cell line (A549)
Objective: Some lichens are known to demonstrate anticancer activity. However, to the best of our knowledge, no information is available about the activity of Usnea longissima against human lung cancer A549 cells. This ... -
Effects of Hypericum perforatum and Hippophae rhamnoides extracts on indomethacin-induced gastric oxidative stress in rats
Turan, Mehmet İbrahim; Bilen, Habib; Demiryılmaz, İsmail; Özgeriş, Fatma Betül; Baykal, Hüseyin; Türkoğlu, Murat; Süleyman, Halis (Allied Acad, 2013)We investigate the effects of Hypericum perforatum (HP) and Hippophae rhamnoides (HR) extracts on indomethacin-induced gastric injury. Rats were divided into five groups each containing 10 animals. the first group received ... -
Effects of nimesulide on the small intestine mucositis induced by methotrexate in rats
Arslan, Aynur; Özçiçek, Adalet; Süleyman, Bahadır; Çoban, Taha Abdulkadir; Çimen, Ferda Keskin; Nalkıran, Hatice Sevim; Kuzucu, Mehmet; Altuner, Durdu; Çetin, Nihal; Süleyman, Halis (Int Press Editing Centre Inc, 2016)Intestinal mucositis is one of the major problems in the patients receiving cancer treatment. Nimesulide is a drug with antioxidant, antiinflammatory and antiulcer features. We aimed to investigate the effect of nimesulide ... -
The effects of thiamine and thiamine pyrophosphate on alcohol-induced hepatic damage biomarkers in rats
Yılmaz, İsmayil; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Çetin, Nihal; Gül, Mehmet Ali; Süleyman, Halis (Verduci Publisher, 2015)OBJECTIVE: This study examined the effects of thiamine and thiamine pyrophosphate on oxidative damage developing in association with hepatic injury caused by alcohol toxicity in rats and on hepatic injury markers. MATERIALS ... -
Effects of thiamine and thiamine pyrophosphate on epileptic episode model established with caffeine in rats
Turan, Mehmet İbrahim; Tan, Hüseyin; Çetin, Nihal; Süleyman, Halis; Çayır, Atilla (Elsevier, 2014)This study examines the effect of thiamine (TH) and thiamine pyrophosphate (TPP) on epileptic episode model induced in rats with caffeine. Animals were divided into groups and given TH or TPP at doses of 10, 30 or 50 mg/kg ... -
Examination of the effects of thiamine and thiamine pyrophosphate on doxorubicin-induced experimental cardiotoxicity
Polat, Bülent; Süleyman, Halis; Şener, Ebru; Akçay, Fatih (Sage Publications Inc, 2015)Background and Purpose: To investigate the effect of thiamine and thiamine pyrophosphate on doxorubicin-induced cardiotoxicity biochemically and histopathologically and to examine whether doxorubicin cardiotoxicity is ... -
Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary
Kumbasar, Serkan; Çetin, Nihal; Yapca, Ömer Erkan; Şener, Ebru; İsaoğlu, Ünal; Yılmaz, Mehmet; Salman, Süleyman; Aksoy, Ayşe Nur; Gül, Mehmet Ali; Süleyman, Halis (Univ Federal Santa Maria, 2014)In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ... -
Gene expression and histopathological evaluation of thiamine pyrophosphate on optic neuropathy induced with ethambutol in rats
Çinici, Emile; Çetin, Nihal; Süleyman, Bahadır; Altuner, Durdu; Yaralı, Oğuzhan; Balta, Hilal; Çalık, İlknur; Tümkaya, Levent; Süleyman, Halis (Ijo Press, 2016)AIM: To compare the effects of thiamine pyrophosphate (TPP) and thiamine (TM) in oxidative optic neuropathy in rats induced by ethambutol. METHODS: the animals were divided into four groups: a control group (CG), an ... -
The impaired balances of oxidant/antioxidant and COX-1/COX-2 in ovarian ischemia-reperfusion injury and prevention by Nimesulide
İsaoğlu, Ünal; Yılmaz, Mehmet; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Bilen, Habib; Yapca, Ömer Erkan; Demiryılmaz, İsmail; İsaoğlu, Neslihan; Gül, Mehmet Ali; Kumbasar, Serkan; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2012)The aims of this study were to investigate the association of ovarian I/R injury with oxidant/antioxidant and cyclooxygenase activity and to examine the effect of nimesulide in I/R injury. Rats were divided into four groups: ... -
Investigating the effect of prunus laurocerasus fruit extract in type II diabetes induced rats
Turan, Mehmet İbrahim; Türkoğlu, Murat; Dündar, Cihat; Çelik, Nuray; Süleyman, Halis (Asian Network Scientific Information-Ansinet, 2013)Prunus laurocerasus (PL) is the fruits of the officinalis species in the Rosaceae family. It is used as diuretic, antidiabetic, antiulcer, dermatitis and hemorrhoids. This study investigate the antidiabetic effects of PL ...
