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Toplam kayıt 19, listelenen: 11-19
Influences of periodontitis on hippocampal inflammation, oxidative stress, and apoptosis in rats
(Wiley, 2021)
Background and aim The hippocampus, which has a central role in cognitive and behavioral activities, is one of the most sensitive parts of the brain to systemic inflammatory diseases. This animal study aims to comprehensively ...
The hepatoprotective potential of resveratrol in an experimental model of ruptured abdominal aortic aneurysm via oxidative stress and apoptosis
(Wiley, 2021)
The mortality rate in ruptured abdominal aortic aneurysms can today be reduced through cardiovascular surgery. However, ischemia and reperfusion-induced tissue damage develop due to aortic cross-clamping applied during ...
Syringic acid protects against thioacetamide-induced hepatic encephalopathy: Behavioral, biochemical, and molecular evidence
(Elsevier, 2021)
The objective of this study was to elucidate the effects of syringic acid on thioacetamide-induced hepatic encephalopathy which is a complex serious syndrome with neuropsychiatric abnormalities related to acute liver ...
Effect of chrysin on endoplasmic reticulum stress in a rat model of testicular torsion
(Taylor & Francis Ltd., 2021)
Background The purpose of this study was to evaluate the possible therapeutic effect of chrysin (CHS) on testicular torsion/detorsion (T/D) injury in vivo through the mechanisms of oxidative stress and endoplasmic reticulum ...
p-Coumaric acid alleviates cisplatin-induced ovarian toxicity in rats
(Wiley, 2021)
Objective The therapeutic value of cisplatin (CDDP) as an anticancer drug is limited by its ovo-otoxicity. The effect of natural phenolic acids in the prevention of many diseases related to oxidative stress has been reported. ...
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats
(Taylor & Francis Ltd., 2021)
The aim of the present study was to evaluate the protective effect of gallic acid (GA) against cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was generated with CDDP (5 mg/kg) intraperitoneally ...
The effect of bee pollen on reproductive and biochemical parameters in methotrexate-induced testicular damage in adult rats
(De Gruyter Open Ltd., 2021)
Objectives: Methotrexate (MTX) is an anticancer drug used in chemotherapy. MTX was known for its toxic effects involving most of the organs including testis. Bee pollen is healthy food for human and has antioxidant effect. ...
Therapeutic effects of carvacrol on beta-amyloid-induced impairments in in vitro and in vivo models of Alzheimer's disease
(Wiley, 2021)
Due to the complex nature of Alzheimer's disease (AD), it is important to investigate agents with multiple effects in the treatment of AD. Carvacrol possesses anti-acetylcholinesterase, anti-oxidant, and neuroprotective ...
The effects of dexmedetomidine against ruptured abdominal aortic aneurysm injury to myocardial tissue induced by abdominal aorta clamping
(Effect Publishing Agency ( EPA ), 2021)
Objectives: This study aims to examine the potential protective effect of the selective alpha-2 adrenergic receptor agonist dexmedetomidine
(DEX) against aortic occlusion-induced myocardial injury.
Patients and methods: ...