Search
Now showing items 1-10 of 37
Synthesis and antioxidant activities of some new triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings
(Taylor & Francis Ltd, 2015)
Various triheterocyclic compounds containing benzimidazole, thiophene, and 1,2,4-triazole rings (3-6) were synthesized and screened for their antioxidant activities. the structures of the synthesized compounds (2-6) were ...
Synthesis and molecular docking study of some 5,6-dichloro-2cyclopropyl-1H-benzimidazole derivatives bearing triazole, oxadiazole, and imine functionalities as potent inhibitors of urease
(Pergamon-Elsevier Science Ltd, 2017)
A new series of benzimidazole compounds including hydrazinecarbothioamide, 1,2,4-triazole, 1,3,4-oxadiazole and imine function were synthesized starting from 5,6-dichloro-2-cyclopropyl-1H-benzimidazole. All of the benzimidazole ...
Synthesis of new coumarin containing benzimidazole derivatives
(Science Reviews 2000 Ltd, 2015)
This study describes the synthesis of a new series of benzimidazoles that contain a coumarin moiety. the high yielding synthetic reaction was between hydrazide derivatives of benzimidazoles and 3-(1H-benzotriazol-1-ylcar ...
Microwave-assisted synthesis of some new coumarin derivatives including 1,2,4-triazol-3-one and investigation of their biological activities
(Springer, 2015)
By using the microwave technology, a new protocol has been developed for the synthesis of new coumarin derivatives including 1,2,4-triazol-3-one skeleton. This protocol proves to be efficient and environmentally friendly ...
Synthesis and evaluation of alpha-glucosidase and pancreatic lipase inhibition by quinazolinone-coumarin hybrids
(Springer, 2016)
A new series of 2-substituted quinazolin-4(3H)-one derivatives including coumarin nucleus has been synthesized and screened for their lipase and a-glucosidase inhibition properties. Among the synthesized compounds, ...
Efficient Synthesis of Benzimidazoles Containing 1,2,4-Triazol-3-One Nucleus Using Microwave Technique
(Springer, 2016)
A series of new compounds containing both benzimidazole and 1,2,4-triazol-3-one rings was synthesized by microwave irradiation of mixtures containing 5-(alkyl/phenyl)-4-(4-carboxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones ...
A simple and efficient synthesis of novel inhibitors of alpha-glucosidase based on benzimidazole skeleton and molecular docking studies
(Academic Press Inc Elsevier Science, 2016)
A novel series of benzimidazole derivatives were prepared starting from o-phenylenediamine and 4-nitro-o-phenylenediamine with iminoester hydrochlorides. Acidic proton in benzimidazole was exchanged with ethyl bromoacetate, ...
Design, Synthesis, and Biological Evaluation of Coumarin-Triazole Hybrid Molecules as Potential Antitumor and Pancreatic Lipase Agents
(Wiley-V C H Verlag Gmbh, 2017)
The design, synthesis, and investigation of antitumor and anti-lipase activities of some coumarin-triazole hybrid molecules are reported. the synthesis of these hybrid molecules was performed under microwave irradiation ...
Rapid and efficient synthesis of a new series of 2-aryl-5-fluoro-6(4-phenylpiperazin-1-yl)-1H-benzimidazoles using microwave heating
(Sage Publications Ltd, 2015)
A new series of 2-aryl-5-fluoro-6-(4-phenylpiperazin-1-yl)-1H-benzimidazoles was synthesised from the reaction of 4-fluoro-5-(4-phenylpiperazin-1-yl) benzene-1,2-diamine and iminoester hydrochlorides. 4-Fluoro-5-(4-pheny ...
Microwave-promoted synthesis and biological activity of some 2-hetarylmethyl-4-(4-hetarylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one derivatives
(Springer, 2015)
A series of fused and non-fused 1,2,4-triazole derivatives were prepared starting from ethyl 4-[1-(2-ethoxy-2-oxoethyl)-3-methyl-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl]benzoate. Firstly, both ethyl ester groups were ...
