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The Impact of Resveratrol on Oxidative Stress Induced by Methotrexate in Rat Ileum Tissue: Evaluation of Biochemical and Histopathological Features and Analysis of Gene Expression 

Ozcicek, Adalet; Cetin, Nihal; Cimen, Ferda Keskin; Tumkaya, Levent; Malkoc, Ismail; Gulaboglu, Mine; Suleyman, Bahadir (Karger, 2016)
Objective: the aim of this study was to assess the impact of resveratrol (RST) on oxidative stress induced by methotrexate in rat ileum tissue. Materials and Methods: Twenty-four rats were divided into 4 groups with 6 in ...

The effect of exposure of rats during prenatal period to radiation spreading from mobile phones on renal development 

Bedir, Recep; Tumkaya, Levent; Sehitoglu, Ibrahim; Kalkan, Yildiray; Yilmaz, Adnan; Sahin, Osman Zikrullah (Informa Healthcare, 2015)
Background: the aim of this study was to investigate the effects of exposure to a 900-MHz electromagnetic field (EMF) produced by mobile phones on the renal development of prenatal rats. Histopathological changes and ...

Protective Effect of Infliximab Against Carbon Tetrachloride-Induced Hepatotoxicity 

Sehitoglu, Ibrahim; Tumkaya, Levent; Bedir, Recep; Ozer, Ender; Cure, Medine Cumhur; Kalkan, Yildiray; Cure, Erkan (Begell House Inc, 2015)
Carbon tetrachloride (CCl4), a solvent frequently used in industry, can cause acute liver failure and liver fibrosis. Infliximab (Ib), a potent tumor necrosis factor alpha blocker, has a protective effect on the liver. ...

A novel model approach for esophageal burns in rats: A comparison of three methods 

Kalkan, Yildiray; Tumkaya, Levent; Akdogan, Remzi Adnan; Yucel, Ahmet Fikret; Tomak, Yakup; Sehitoglu, Ibrahim; Kurt, Aysel (Sage Publications Inc, 2015)
Background: Corrosive esophageal injury causes serious clinical problems. We aimed to create a new experimental esophageal burn model using a single catheter without a surgical procedure. Materials and methods: We conducted ...

The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats 

Erkut, Adem; Tumkaya, Levent; Balik, Mehmet Sabri; Kalkan, Yildiray; Guvercin, Yilmaz; Yilmaz, Adnan; Sehitoglu, Ibrahim (Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ...

Protective Effects of Infliximab on Lung Injury Induced by Methotrexate 

Kurt, Aysel; Tumkaya, Levent; Turut, Hasan; Cure, Medine Cumhur; Cure, Erkan; Kalkan, Yildiray; Acipayam, Ahmet (Elsevier Espana Slu, 2015)
Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ...

The protective effect of infliximab against carbon tetrachloride-induced acute lung injury 

Kurt, Aysel; Tumkaya, Levent; Yuce, Suleyman; Turut, Hasan; Cure, Medine Cumhur; Sehitoglu, Ibrahim; Cure, Erkan (Mashhad Univ Med Sciences, 2016)
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ...

The Effects of Curcumin on Wound Healing in a Rat Model of Nasal Mucosal Trauma 

Emiroglu, Gokhan; Coskun, Zerrin Ozergin; Kalkan, Yildiray; Erdivanli, Ozlem Celebi; Tumkaya, Levent; Terzi, Suat; Dursun, Engin (Hindawi Ltd, 2017)
We explored the effects of topical curcumin on the healing of nasal mucosal wounds. A total of 32 Sprague-Dawley Albino rats were randomized in equal numbers into four groups, and unilateral nasal wounds were created using ...

Mobile phone radiation during pubertal development has no effect on testicular histology in rats 

Tumkaya, Levent; Kalkan, Yildiray; Bas, Orhan; Yilmaz, Adnan (Sage Publications Inc, 2016)
Mobile phones are extensively used throughout the world. There is a growing concern about the possible public health hazards posed by electromagnetic radiation emitted from mobile phones. Potential health risk applies ...

Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction 

Cure, Erkan; Kirbas, Aynur; Tumkaya, Levent; Cure, Medine Cumhur; Kalkan, Yildiray; Yilmaz, Arif; Yuce, Suleyman (Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...
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Tumkaya, Levent (57)
Mercantepe, Tolga (27)Kalkan, Yildiray (25)Yilmaz, Adnan (24)Cure, Erkan (9)Topcu, Atilla (9)Mercantepe, Filiz (8)Sehitoglu, Ibrahim (8)Cure, Medine Cumhur (7)Dursun, Engin (7)... View MoreSubjectrat (10)Oxidative stress (8)oxidative stress (8)Rat (7)[0-Belirlenecek] (6)Apoptosis (5)Cisplatin (5)Caspase-3 (4)Electromagnetic field (4)kidney (4)... View MoreDate Issued9000 - 9999 (2)2014 - 2999 (55)Has File(s)No (57)

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