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The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation 

Kostakoglu, Ugur; Topcu, Atilla; Atak, Mehtap; Tumkaya, Levent; Mercantepe, Tolga; Uydu, Huseyin Avni (Pergamon-Elsevier Science Ltd, 2020)
Aims: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2.38 million people a year die from respiratory ...

An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats 

Topcu, Atilla; Balik, Gulsah; Atak, Mehtap; Mercantepe, Tolga; Uydu, Huseyin Avni; Tumkaya, Levent (Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...

Protective effects of amifostine, curcumin and melatonin against cisplatin-induced acute kidney injury (vol 391, pg 915, 2018) 

Mercantepe, Filiz; Mercantepe, Tolga; Topcu, Atilla; Yilmaz, Adnan; Tumkaya, Levent (Springer, 2019)
[No abstract available]

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats 

Mercantepe, Tolga; Topcu, Atilla; Rakici, Sema; Tumkaya, Levent; Yilmaz, Adnan; Mercantepe, Filiz (Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...

Protective effects of nebivolol on ovarian ischemia-reperfusion injury in rat 

Colak, Sabri; Gurlek, Beril; Topcu, Atilla; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan (Wiley, 2020)
Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7-7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) and histopathological changes in ...

Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury 

Mercantepe, Filiz; Mercantepe, Tolga; Topcu, Atilla; Yilmaz, Adnan; Tumkaya, Levent (Springer, 2018)
Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ...

An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats 

Topcu, Atilla; Mercantepe, Filiz; Rakici, Sema; Tumkaya, Levent; Uydu, Huseyin Avni; Mercantepe, Tolga (Springer, 2019)
According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ...

Protective Effect of Tea Grape Extract on Cisplatin-Induced Muscle Atrophy: A Morphological Study 

Balik, Mehmet Sabri; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan; Balik, Gulsah; Topcu, Atilla; Yazici, Zihni (Kowsar Publ, 2018)
Background: Even though Cisplatin (Cis) is known to be organotoxic, it is used in neoplastic chemotherapy. in skeletal muscles, the toxic effect manifests as atrophy. Objectives: the tea grape extract (TGE) is a sort of ...



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Mercantepe, Tolga (8)
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Tumkaya, Levent (8)
Yilmaz, Adnan (5)Mercantepe, Filiz (4)Uydu, Huseyin Avni (3)Atak, Mehtap (2)Balik, Gulsah (2)Rakici, Sema (2)Balik, Mehmet Sabri (1)... View MoreSubjectOxidative stress (4)Rat (4)Cisplatin (2)N-Acetylcysteine (2)[0-Belirlenecek] (1)Amifostine (1)Apoptosis (1)apoptosis (1)Atrophy (1)Cecal ligation and puncture (1)... View MoreDate Issued2019 (4)2018 (2)2020 (2)Has File(s)
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