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Küçük Resim

Effect of 900-MHz electromagnetic field on the cerebellum: a histopathological investigation 

Mercantepe, Tolga; Tümkaya, Levent; Gökçek, Mehmet Fatih; Suzan, Zehra Topal; Esmer, Erva (2018)
Objectives: The currently widely used technological devices give rise to electromagnetic fields (EMFs) at various frequencies. Recent studies have reported that EMFs damage the central nervous system. The cerebellum is of ...
Küçük Resim

The protective effects of perindopril against acute kidney damage caused by septic shock 

Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya Kılıç; Tümkaya, Levent; Batçık, Şule; Pınarbaş, Esra; Uydu, Hüseyin Avni (Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
Küçük Resim

Protective effect of astaxanthin against cisplatin-induced gastrointestinal toxicity in rats 

Yılmaz, Yeliz; Tümkaya, Levent; Mercantepe, Tolga; Akyıldız, Kerimali (Springer Wien, 2022)
Background the aim of the present study was to demonstrate astaxanthin's attenuating effects against cisplatin (CIS)-induced gastrointestinal toxicity in a rat model. Methods Thirty-two Wistar rats (weight 200-250 g) were ...
Küçük Resim

The effect of imatinib administered in the prenatal period on testis development in rats 

Suzan, Zehra Topal; Tümkaya, Levent; Mercantepe, Tolga; Atak, Muhammed; Uydu, Hüseyin Avni (Sage Publications Ltd, 2021)
Background: the purpose of this study was to examine the effects of exposure to imatinib in the prenatal period on testis development in rats. Methods: Although all the study groups received intraperitoneal imatinib on ...
Küçük Resim

Resveratrol prevents acute renal injury in a model of ruptured abdominal aortic aneurysm 

Hemşinli, Doğuş; Tümkaya, Levent; Ergene, Şaban; Karakişi, Sedat Ozan; Mercantepe, Tolga; Çınar, Şenay Burak; Yılmaz, A. (Sage Publications Ltd, 2021)
Objective: To examine the biochemical and histopathological effects of ischemia/reperfusion (I/R) injury in a ruptured abdominal aortic aneurysm (RAAA) model in rats, and to investigate the potential protective role of ...
Küçük Resim

Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction 

Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Akyıldız, Kerimali; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar; Yılmaz, Adnan (Elsevier, 2021)
It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ...
Küçük Resim

The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats 

Topçu, Atilla; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Tümkaya, Levent; Yılmaz, Adnan (Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
Küçük Resim

The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis 

Yıldız, İlknur Esen; Topçu, Atilla; Bahçeci, İlkay; Arpa, Medeni; Tümkaya, Levent; Mercantepe, Tolga; Batçık, Şule; Yıldız, Yasin (Pergamon-Elsevier Science Ltd., 2021)
Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ...
Küçük Resim

The protective effects of topiramate on intestinal injury induced with infrarenal aortic occlusion via oxidative stress and apoptosis 

Pergel, Ahmet; Demiral, Gökhan; Tümkaya, Levent; Mercantepe, Tolga; Özdemir, Ali; Kalcan, Süleyman; Çolakoğlu, Muhammed Kadri; Yılmaz, Adnan; Bedir, Recep; Karakaya, Ahmet (Taylo & Francis Ltd., 2021)
Purpose: Prolonged surgical procedures and some clinical conditions such as surgeries of thoracoabdominal aorta, mesenteric ischemia, cardiopulmonary bypass, strangulated hernias and neonatal necrotizing enterocolitis may ...
Küçük Resim

Periodontitis exacerbates the renal degenerative effects of obesity in rats 

Kurt-Bayrakdar, Sevda; Köse, Oğuz; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2021)
Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ...
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Mercantepe, Tolga (105)
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