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Toplam kayıt 4, listelenen: 1-4
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...
Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats
(E-Century Publishing Corp, 2015)
This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ...
Effect of infliximab on renal injury due to methotrexate in rat
(Iranian Soc Nephrolgy, 2015)
Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ...
Protective effects of infliximab on lung injury induced by methotrexate
(Elsevier Espana Slu, 2015)
Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ...