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Toplam kayıt 5, listelenen: 1-5
Infliximab modulates cisplatin-induced hepatotoxicity in rats
(Galenos Publ, 2016)
Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ...
The protective effect of adalimumab on renal injury in a model of abdominal aorta cross-clamping
(Wroclaw Medical Univ, 2016)
Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process. Objectives. the ...
Protective effects of thymoquinone and alpha-tocopherol on the sciatic nerve and femoral muscle due to lower limb ischemia-reperfusion injury
(Verduci Publisher, 2016)
OBJECTIVE: Thymoquinone (TQ) is an antioxidant and anti-apoptotic substance found in the Nigella sativa plant. Alpha-tocopherol (alpha-TP) is a potent antioxidant. We aimed to determine whether or not TQ and TP have a ...
Biochemical, histopathological and immunohistochemieal evaluation of the protective and therapeutic effects of thymoquinone against ischemia and ischemia/reperfusion injury in the rat ovary
(Karger, 2016)
Aim: To evaluate the antioxidant effects of thymoquinone (TQ) and to investigate the biochemical, histopathological and immunohistochennical changes in experimental rat ovarian torsion. Methods: A total of 48 female adult ...
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
(Mashhad Univ Med Sciences, 2016)
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ...