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Synthesis of novel 2,3-disubstituted quinazolin-4(3H)-one derivatives containing hydrazone skeleton as potent urease inhibitors and their antimicrobial activities
A new series of quinazolinones containing hydrazone moiety were synthesized, and their inhibitory activities on urease were assessed in vitro. Most of the compounds exhibited potent urease inhibitory activity. Among the ...
SYNTHESIS, INHIBITORY PROPERTIES ON THE METABOLIC ENZYMES AND ANTIOXIDANT ACTIVITY OF A NEW SERIES BENZIMIDAZOLE DERIVATIVES
(Editura Acad Romane, 2019)
In this study, a series of new 1, 2-disubstituted benzimidazole was synthesized starting from 5, 6-dichloro-2-(4-methoxybenzyl)-1H-benzimidazole compound which was converted to the ester and hydrazide derivative, respectively. ...