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Prenatal Dönemde 900Mhz Elektromanyetik Alanın Sıçan Omurilik Dokusu Üzerine Etkilerinin Histopatolojik Olarak İncelenmesi 

Mercantepe, Tolga; Tümkaya, Levent; Gökçe, Fatih Mehmet; Uzunok, Barış; Suzan, Zehra Topal; Çınar, Seda; Esmer, Erva (2018)
Amaç: Günümüzde yaşantımıza giren ve giderek artan belli bir frekansta elektromanyetik dalga yayılımına neden olan teknolojik cihazlar insanları elektromanyetik alana maruz bırakmaktadır. Bu cihazlar tarafından yayılan ...

Protective effects of amifostine, curcumin, and melatonin against cisplatin-induced acute kidney injury 

Mercantepe, Filiz; Mercantepe, Tolga; Topcu, Atilla; Yilmaz, Adnan; Tumkaya, Levent (Springer, 2018)
Despite the enormous advances made in the field of oncology, no solution to the side effect of nephrotoxicity caused by cisplatin used as an antineoplastic agent for approximately 40 years has yet been discovered. This ...

Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity 

Mercantepe, Tolga; Kalkan, Yildiray; Tumkaya, Levent; Sehitoglu, Ibrahim; Mercantepe, Filiz; Yildirmis, Sermet (Wroclaw Medical Univ, 2018)
Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...

Protective effects of amifostine, curcumin and caffeic acid phenethyl ester against cisplatin-induced testis tissue damage in rats 

Mercantepe, Tolga; Unal, Deniz; Tumkaya, Levent; Yazici, Zihni Acar (Spandidos Publ Ltd, 2018)
Cisplatin is an effective antineoplastic drug that is usually used to treat a number of different types of cancer in the clinic. One of the most notable side effects of cisplatin use is infertility. the present study was ...

A novel therapeutics agent: antioxidant effects of hydroxylfasudil on rat kidney and liver tissues in a protamine sulphate-induced cystitis rat model; preliminary results 

Bozkurt, Aliseydi; Budak, Harun; Erol, Huseyin Serkan; Can, Serpil; Mercantepe, Tolga; Akin, Yigit; Coban, T. Abdulkadir (Taylor & Francis Ltd, 2018)
Cystitis is defined as an inflammation of the bladder caused by a bacterial infection, and it can be dangerous and painful when it spreads through the internal organs. in this study, antioxidant effects of hydroxylfasudil ...

Effects of gadolinium-based MRI contrast agents on liver tissue 

Mercantepe, Tolga; Tumkaya, Levent; Celiker, Fatma Beyazal; Suzan, Zehra Topal; Cinar, Seda; Akyildiz, Kerimali; Yilmaz, Adnan (Wiley, 2018)
BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...

Pathological Findings Observed in the Kidneys of Postnatal Male Rats Exposed to the 2100 MHz Electromagnetic Field 

Bedir, Recep; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan (Elsevier Science Inc, 2018)
Background. the widespread use by young people of modern communication devices such as mobile phones means that they are particularly exposed to electromagnetic fields (EMF) and other problems. However, few studies have ...

Effects of Infliximab against Methotrexate Toxicity in Splenic Tissue via the Regulation of CD3, CD68, and C200R in Rats 

Mercantepe, Tolga; Tumkaya, Levent; Mercantepe, Filiz (Karger, 2018)
Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ...

Protective Effect of Tea Grape Extract on Cisplatin-Induced Muscle Atrophy: A Morphological Study 

Balik, Mehmet Sabri; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan; Balik, Gulsah; Topcu, Atilla; Yazici, Zihni (Kowsar Publ, 2018)
Background: Even though Cisplatin (Cis) is known to be organotoxic, it is used in neoplastic chemotherapy. in skeletal muscles, the toxic effect manifests as atrophy. Objectives: the tea grape extract (TGE) is a sort of ...

Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence 

Hanci, Hatice; Kerimoglu, Gokcen; Mercantepe, Tolga; Odaci, Ersan (Pergamon-Elsevier Science Ltd, 2018)
The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and ...
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Tumkaya, Levent (8)Yilmaz, Adnan (5)Mercantepe, Filiz (3)Suzan, Zehra Topal (2)Topcu, Atilla (2)Akca, Gorkem (1)Akin, Yigit (1)Akyildiz, Kerimali (1)Balik, Gulsah (1)... View MoreSubjectCisplatin (3)Electromagnetic field (2)liver (2)Nephrotoxicity (2)rat (2)adalimumab (1)Adolescence (1)Amifostine (1)amifostine (1)Antioxidant (1)... View MoreDate Issued
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