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Protective effects of nebivolol on ovarian ischemia-reperfusion injury in rat

Colak, Sabri; Gurlek, Beril; Topcu, Atilla; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan (Wiley, 2020)

Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7-7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) and histopathological changes in ...

Effects of Gadodiamide and Gadoteric Acid on Rat Kidneys: A Comparative Study

Celiker, Fatma Beyazal; Tumkaya, Levent; Mercantepe, Tolga; Beyazal, Mehmet; Turan, Arzu; Beyazal Polat, Hatice; Yilmaz, Adnan (Wiley, 2019)

Background Gadolinium-based contrast agents are complex chelates to provide contrast in NRI. However, recent studies have highlighted the deposition of free Gd+3 ion in various tissues. Purpose To evaluate the histopathological ...

Protective effects of tumor necrosis factor alpha inhibitors on methotrexate-induced pancreatic toxicity

Mercantepe, Tolga; Kalkan, Yildiray; Tumkaya, Levent; Sehitoglu, Ibrahim; Mercantepe, Filiz; Yildirmis, Sermet (Wroclaw Medical Univ, 2018)

Background. Methotrexate (MTX), a folate antagonist, is commonly used in the treatment of many different types of cancer and inflammatory diseases, including pancreatic cancer, although its side effects on the pancreas ...

Effects of gadolinium-based MRI contrast agents on liver tissue

Mercantepe, Tolga; Tumkaya, Levent; Celiker, Fatma Beyazal; Suzan, Zehra Topal; Cinar, Seda; Akyildiz, Kerimali; Yilmaz, Adnan (Wiley, 2018)

BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ...