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Toplam kayıt 6, listelenen: 1-6
Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats
(Hindawi Ltd, 2014)
The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ...
Infliximab modulates cisplatin-induced hepatotoxicity in rats
(Galenos Publ, 2016)
Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ...
Protective effect of infliximab on methotrexate-induced liver injury in rats: Unexpected drug interaction
(Wolters Kluwer Medknow Publications, 2015)
Aims: Although methotrexate (mtx) is a widely used agent to treat cancer and inflammatory diseases, its hepatotoxic effect limits for clinical utility. We aimed to investigate whether infliximab (inf), an inhibitor of tumor ...
Effect of infliximab on renal injury due to methotrexate in rat
(Iranian Soc Nephrolgy, 2015)
Introduction. Methotrexate, an antagonist of folic acid used in the treatment of many cancers and inflammatory diseases, is associated with side effects that limit its usage. Infliximab has been reported to have a protective ...
Protective effects of infliximab on lung injury induced by methotrexate
(Elsevier Espana Slu, 2015)
Introduction: Methotrexate (MTX) is used to treat cancers, several forms of arthritis and other rheumatic conditions, although MIX may cause pulmonary toxicity related to the production of free oxygen radicals, various ...
The protective effect of infliximab against carbon tetrachloride-induced acute lung injury
(Mashhad Univ Med Sciences, 2016)
Objective(s): Carbon tetrachloride (CCl4) causes pulmonary toxicity. Infliximab (Ib) is a potent inhibitor of tumor necrosis factor-alpha (TNF-alpha). We aimed to investigate whether Ib has a protective effect on CCl4 ...