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Sciatic nerve injury following analgesic drug injection in rats: a histopathological examination 

Bostan, Habib; Çabalar, Murat; Altınay, Serdar; Kalkan, Yıldıray; Tümkaya, Levent; Kanat, Ayhan; Koçer, Abdulkadir (Kare PUBL, 2018)
OBJECTIVE: Sciatic nerve neuropathy can be observed following intramuscular gluteal injections. The histopathological examination of sciatic nerve damage following intramuscular injection in the gluteal region for acute ...
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Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats 

Cüre, Erkan; Cüre, Medine Cumhur; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İbrahim; Kırbaş, Aynur; Yılmaz, Arif; Yüce, Süleyman; Gökçe, Mehmet Fatih (Wolters Kluwer Medknow Publications, 2014)
Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ...
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Adalimumab ameliorates abdominal aorta cross clamping which induced liver injury in rats 

Cüre, Erkan; Cüre, Medine Cumhur; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İbrahim; Kırbaş, Aynur; Yılmaz, Arif; Yüce, Süleyman; Yücel, Ahmet Fikret (Hindawi Ltd, 2014)
The aim of this study was to investigate the possible protective effects of adalimumab (ADA) on cell damage in rat liver tissue during ischemia/reperfusion (I/R) injury of infrarenal abdominal aorta. Thirty male Wistar-albino ...
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Influence of infliximab pretreatment on ischemia/reperfusion injury in rat intestine 

Akdoğan, Remzi Adnan; Kalkan, Yıldıray; Tümkaya, Levent; Alacam, Hasan; Erdivanlı, Başar; Aydın, İbrahim (Via Medica, 2014)
The Pringle maneuver is used in hepatic surgery to prevent blood loss but is associated with ischemia-reperfusion injury. To investigate the effect of infliximab on inflammation and apoptosis in rat intestinal mucosa during ...
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Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats 

Aras, Adem Bozkurt; Güven, Mustafa; Akman, Tarık; Özkan, Adile; Şen, Halil Murat; Düz, Uğur; Kalkan, Yıldıray; Coşkun, Şilan; Coşar, Murat (Shenyang Editorial Dept Neural Regeneration Res, 2015)
Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia. Rat models of middle cerebral artery occlusion were intraperitoneally ...
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Infliximab modulates cisplatin-induced hepatotoxicity in rats 

Cüre, Medine Cumhur; Cüre, Erkan; Kalkan, Yıldıray; Kırbaş, Aynur; Tümkaya, Levent; Yılmaz, Arif; Türkyılmaz, Ayşegül Küçükali; Sehitoğlu, İbrahim; Yüce, Süleyman (Galenos Publ, 2016)
Background: Cisplatin (Cis) is one of the most com-monly used antineoplastic drugs. It is used as chemo-therapy for many solid organ malignancies such as brain, neck, male and female urogenital, vesical and pulmonary ...
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The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats 

Erkut, Adem; Tümkaya, Levent; Balık, Mehmet Sabri; Kalkan, Yıldıray; Güvercin, Yılmaz; Yılmaz, Adnan; Yüce, Süleyman; Cüre, Erkan; Şehitoğlu, İbrahim (Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ...
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The acute effects of preoperative ozone theraphy on surgical wound healing 

Şahin, Hasan; Şimşek, Tuncer; Türkon, Hakan; Kalkan, Yıldıray; Özkul, Faruk; Özkan, M. Turgut Alper; Erbaş, Mesut; Altınışık, Uğur; Demiraran, Yavuz (Acta Cirurgica Brasileira, 2016)
PURPOSE: To investigate the effects of preoperative rectal ozone insufflation on surgical wound healing over the proinflammatory cytokines and histopathological changes. METHODS: Twenty one rabbits were divided into 3 ...
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The protective effect of infliximab on cisplatin-induced intestinal tissue toxicity 

Aydın, İbrahim; Kalkan, Yıldıray; Özer, Ezgi Demir; Yücel, Ahmet Fikret; Pergel, Ahmet; Cüre, Erkan; Cüre, Medine Cumhur; Şahin, Dursun Ali (Verduci Publisher, 2014)
OBJECTIVE: Cisplatin (CP) is a popular chemotherapeutic agent. However, high doses of CP may lead to severe side effects to the gastrointestinal system. the aim of this study was to investigate the protective effects of ...
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Effect of infliximab against cisplatin-induced nephrotoxicity 

Cüre, Erkan; Kırbaş, Aynur; Tümkaya, Levent; Cüre, Medine Cumhur; Şahin, Osman Zikrullah; Kalkan, Yıldıray; Yüce, Süleyman; Altuner, Durdu (Saudi Med J, 2014)
Objectives: To investigate whether infliximab (Ib), an inhibitor of tumor necrosis factor alpha (TNF-alpha), prevents cisplatin (Cis)-induced nephrotoxicity. Methods: the study was performed in the Department of Internal ...
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