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Küçük Resim

Ratlarda Cisplatinin Oluşturduğu Karaciğer Hasarında Beyaz Çayın Etkisi 

Dizman, Fatih (Recep Tayyip Erdoğan Üniversitesi, Sağlık Bilimleri Enstitüsü, Tıbbi Biyokimya Anabilim Dalı, 2019)
Abstract: The aim of this study was to investigate the reduction or elimination of cisplatin-induced liver damage in chronic white tea-fed rats. For this purpose, 24 female Sprague Dawley rats from 3 groups of 8 were used. ...
Küçük Resim

The protective effect of melatonin and agomelatin against cisplatin-induced nephrotoxicity and oxidative stress in the rat kidney 

Yılmaz, İsmayıl; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Süleyman, Bahadır; Turan, Işıl Şiltelioğlu; Altuner, Durdu; Hakan, Alp Hamit; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2013)
Cisplatin is used to treat various types of cancers. Its use is limited, however, due to nephrotoxicity, which may result from free radical damage. Evidence exists that melatonin reduces oxidative stress-induced damage. ...
Küçük Resim

The role of antioxidant activity in the prevention and treatment of infertility caused by cisplatin in rats 

Aksoy, Ayşe Nur; Kücür, Suna Kabil; Batmaz, Gonca; Gözükara, İlay; Aksoy, Mehmet; Kurt, Nezahat; Mammadov, Renad (Karger, 2015)
Background/Aims:To investigate the importance of antioxidant activity in infertility caused by cisplatin in rats. Methods: Rats in cisplatin control (CG), Vitamin E+cisplatin (ECG), Vitamin C + cisplatin (CCG), Hippophae ...
Küçük Resim

Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats 

Ayazoğlu Demir, Elif; Menteşe, Ahmet; Livaoğlu, Ayten; Türkmen Alemdar, Nihal; Demir, Selim (Taylor & Francis Ltd., 2021)
The aim of the present study was to evaluate the protective effect of gallic acid (GA) against cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was generated with CDDP (5 mg/kg) intraperitoneally ...
Küçük Resim

Suppression of cisplatin-induced ovarian injury in rats by chrysin: an experimental study 

Menteşe, Ahmet; Türkmen Alemdar, Nihal; Livaoğlu, Ayten; Demir, Elif Ayazoğlu; Aliyazıcıoğlu, Yüksel; Demir, Selim (Taylor & Francis Ltd., 2022)
The aim of this study was to investigate the potential therapeutic efficacy of chrysin (CHS) against ovotoxicity caused by intraperitoneal administration of cisplatin (CDDP) in rats. In this experimental study, 24 female ...
Küçük Resim

Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis 

Dil, Eyüp; Topçu, Atilla; Mercantepe, Tolga; Tümkaya, Levent; Akyıldız, Kerimali; Saral, Sinan; Yılmaz, Adnan (Springer, 2023)
Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ...

The effects of white tea (Camellia Sinensis) and infliximab against cisplatin-induced testicular damage via oxidative stress and apoptosis 

Çakıroğlu, Şenay; Mercantepe, Tolga; Tümkaya, Levent; Uydu, Hüseyin Avni; Topçu, Atilla; Atak, Mehtap (2023)
Cisplatin (Cis) is an important chemotherapeutic agent used in cancer treatment. Males exposed to Cis were reported to exhibit testicular toxicity. Cis-induced testicular toxicity is mediated by oxidative stress, inflammation, ...

Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways 

Çiftel, Enver; Mercantepe, Filiz; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Çiftel, Serpil (Springer, 2024)
Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ...

The hepatoprotective effects of camellia sinensis on cisplatin-induced acute liver injury 

Yılmaz, Adnan; Dizman, Fatih; Akyıldız, Kerimali; Mataracı Karakaş, Sibel; Mercantepe, Tolga; Uydu, Hüseyin Avni; Tümkaya, Levent; Öztürk, Köksal (MDPI, 2024)
Acute liver injury is an increasing global health problem. It is a widespread side effect of cisplatin treatment in the clinic and can lead to liver failure if not treated promptly. Previous studies have revealed that green ...



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YazarMercantepe, Tolga (4)Akyıldız, Kerimali (3)Tümkaya, Levent (3)Yılmaz, Adnan (3)Demir, Selim (2)Dizman, Fatih (2)Livaoğlu, Ayten (2)Menteşe, Ahmet (2)Topçu, Atilla (2)Türkmen Alemdar, Nihal (2)... Daha FazlaAnahtar Kelime
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Oxidative stress (5)White Tea (3)Agomelatine (2)Inflammation (2)Infliximab (2)Liver (2)Antioxidant activity (1)Ative stress (1)... Daha FazlaYayın Tarihi2020 - 2024 (6)2013 - 2019 (3)Mevcut Dosya(lar)Tam Metni Olanlar (9)

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