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Küçük Resim

A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue 

Demiryılmaz, İsmail; Şener, Ebru; Çetin, Nihal; Altuner, Durdu; Akçay, Fatih; Süleyman, Halis (Pharmaceutical Soc Korea, 2013)
In this study, the biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia-reperfusion induced oxidative damage in rat ovarian tissue were investigated. Animals were divided into four ...
Küçük Resim

Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes 

Yapca, Ömer Erkan; Turan, Mehmet İbrahim; Börekçi, Bünyamin; Akçay, Fatih; Süleyman, Halis (Mashhad Univ Med Sciences, 2014)
Objective(s): This study investigated the effects of melatonin, famotidine, mirtazapine, and thiamine pyrophosphate on ischemia/ reperfusion (I/ R) injury in diabetic rats and evaluated oxidant and antioxidant marker ...

Benefits of the antioxidant and anti-inflammatory activity of etoricoxib in the prevention of ovarian ischemia/reperfusion injury induced experimentally in rats 

Yapca, Ömer Erkan; Turan, Mehmet İbrahim; Yılmaz, İsmayil; Salman, Süleyman; Gülaboğlu, Mine; Süleyman, Halis (Wiley-Blackwell, 2014)
Aim This study is a biochemical investigation of the effect of etoricoxib, a selective cyclooxygenase (COX)-2 inhibitor, on ischemia/reperfusion (I/R) injury experimentally induced in rat ovaries. Methods Experimental ...
Küçük Resim

Protective effect of edaravone against radiation-induced ovarian injury: a histopathological and immunohistochemical evaluation in an experimental rat model 

Ural, Ülkü Mete; Gürlek, Beril; Alver, Ahmet (Springer Heidelberg, 2021)
Purpose We aimed to evaluate the protective effect of edaravone on radiation-induced ovarian damage in an experimental rat model. Methods Thirty-two Wistar albino female rats were randomly divided into four groups. Group ...

The effect of controlled reperfusion in the prevention of infertility caused by ischemia induced in the contralateral ovary in rats with unilateral ovariectomy 

Aksoy, Ayşe Nur; Aydın, Fatma; Yılmaz, Emsal Pınar Topdağı; Batmaz, Gonca; Süleyman, Bahadır (Karger, 2015)
Background/Aims: To investigate the effectiveness of controlled reperfusion (CR) on ovarian tissue malondialdehyde, total glutathione and 8-hydroxyguanine levels and infertility rates in a rat model of induced ischemia-reperfusion ...
Küçük Resim

The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion 

Topçu, Atilla; Öztürk, Aykut; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Taylor & Francis Ltd., 2022)
Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ...
Küçük Resim

The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway 

Öztürk, Aykut; Topçu, Atilla; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Yılmaz, Eda Kutlu (Wiley, 2022)
Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ...
Küçük Resim

The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation 

Deniz, Esra; Topçu, Atilla; Öztürk, Aykut; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Elsevier, 2022)
Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ...
Küçük Resim

An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats 

Topçu, Atilla; Balık, Gülşah; Atak, Mehtap; Mercantepe, Tolga; Uydu, Hüseyin Avni; Tümkaya, Levent (Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...
Küçük Resim

Protective effects of nebivolol on ovarian ischemia-reperfusion injury in rat 

Çolak, Sabri; Gürlek, Beril; Topçu, Atilla; Tümkaya, Levent; Mercantepe, Tolga; Yılmaz, Adnan (Wiley, 2020)
Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7-7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) and histopathological changes in ...
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YazarTopçu, Atilla (6)Atak, Mehtap (4)Arpa, Medeni (3)Deniz, Esra (3)Mercantepe, Tolga (3)Süleyman, Halis (3)Tümkaya, Levent (3)Öztürk, Aykut (3)Öztürk, Seda Duman (3)Akçay, Fatih (2)... Daha FazlaAnahtar Kelime
Ovary (11)
Rat (11)
Ischemia-reperfusion (5)Oxidative stress (4)Inflammation (3)Ischemia (2)Reperfusion (2)Amiodarone (1)Apoptosis (1)Diabetes mellitus (1)... Daha FazlaYayın Tarihi2020 - 2024 (6)2013 - 2019 (5)Mevcut Dosya(lar)Tam Metni Olanlar (9)Tam Metni Olmayanlar (2)

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