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Küçük Resim

Effects of Hypericum perforatum and Hippophae rhamnoides extracts on indomethacin-induced gastric oxidative stress in rats 

Turan, Mehmet İbrahim; Bilen, Habib; Demiryılmaz, İsmail; Özgeriş, Fatma Betül; Baykal, Hüseyin; Türkoğlu, Murat; Süleyman, Halis (Allied Acad, 2013)
We investigate the effects of Hypericum perforatum (HP) and Hippophae rhamnoides (HR) extracts on indomethacin-induced gastric injury. Rats were divided into five groups each containing 10 animals. the first group received ...
Küçük Resim

The protective effect of melatonin and agomelatin against cisplatin-induced nephrotoxicity and oxidative stress in the rat kidney 

Yılmaz, İsmayıl; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Süleyman, Bahadır; Turan, Işıl Şiltelioğlu; Altuner, Durdu; Hakan, Alp Hamit; Süleyman, Halis (Colegio Farmaceuticos Provincia de Buenos Aires, 2013)
Cisplatin is used to treat various types of cancers. Its use is limited, however, due to nephrotoxicity, which may result from free radical damage. Evidence exists that melatonin reduces oxidative stress-induced damage. ...
Küçük Resim

The protective effects of perindopril against acute kidney damage caused by septic shock 

Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya Kılıç; Tümkaya, Levent; Batçık, Şule; Pınarbaş, Esra; Uydu, Hüseyin Avni (Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
Küçük Resim

The role of antioxidant activity in the prevention and treatment of infertility caused by cisplatin in rats 

Aksoy, Ayşe Nur; Kücür, Suna Kabil; Batmaz, Gonca; Gözükara, İlay; Aksoy, Mehmet; Kurt, Nezahat; Mammadov, Renad (Karger, 2015)
Background/Aims:To investigate the importance of antioxidant activity in infertility caused by cisplatin in rats. Methods: Rats in cisplatin control (CG), Vitamin E+cisplatin (ECG), Vitamin C + cisplatin (CCG), Hippophae ...
Küçük Resim

Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats 

Yücel, Ahmet Fikret; Pergel, Ahmet; Aydın, İbrahim; Alaçam, Hasan; Karabıçak, İlhan; Kesicioğlu, Tuğrul; Tümkaya, Levent; Kalkan, Yıldıray; Arslan, Zakir; Şehitoğlu, İbrahim; Şahin, Dursun Ali (E-Century Publishing Corp, 2015)
This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ...
Küçük Resim

Effects of nimesulide on the small intestine mucositis induced by methotrexate in rats 

Arslan, Aynur; Özçiçek, Adalet; Süleyman, Bahadır; Çoban, Taha Abdulkadir; Çimen, Ferda Keskin; Nalkıran, Hatice Sevim; Kuzucu, Mehmet; Altuner, Durdu; Çetin, Nihal; Süleyman, Halis (Int Press Editing Centre Inc, 2016)
Intestinal mucositis is one of the major problems in the patients receiving cancer treatment. Nimesulide is a drug with antioxidant, antiinflammatory and antiulcer features. We aimed to investigate the effect of nimesulide ...
Küçük Resim

The impact of resveratrol on oxidative stress induced by methotrexate in rat ileum tissue: evaluation of biochemical and histopathological features and analysis of gene expression 

Öçiçek, Adalet; Çetin, Nihal; Çimen, Ferda Keskin; Tuümkaya, Levent; Malkoç, İsmail; Gulaboğlu, Mine; Yaralı, Oğuzhan; Süleyman, Bahadır (Karger, 2016)
Objective: the aim of this study was to assess the impact of resveratrol (RST) on oxidative stress induced by methotrexate in rat ileum tissue. Materials and Methods: Twenty-four rats were divided into 4 groups with 6 in ...
Küçük Resim

The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis 

Yıldız, İlknur Esen; Topçu, Atilla; Bahçeci, İlkay; Arpa, Medeni; Tümkaya, Levent; Mercantepe, Tolga; Batçık, Şule; Yıldız, Yasin (Pergamon-Elsevier Science Ltd., 2021)
Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ...
Küçük Resim

Effect of chrysin on endoplasmic reticulum stress in a rat model of testicular torsion 

Kazaz, İlke Onur; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Alemdar, Nihal Türkmen; Akman, Ahmet Uğur; Çeküç, Ozan Can; Menteşe, Ahmet (Taylor & Francis Ltd., 2021)
Background The purpose of this study was to evaluate the possible therapeutic effect of chrysin (CHS) on testicular torsion/detorsion (T/D) injury in vivo through the mechanisms of oxidative stress and endoplasmic reticulum ...
Küçük Resim

Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats 

Ayazoğlu Demir, Elif; Menteşe, Ahmet; Livaoğlu, Ayten; Türkmen Alemdar, Nihal; Demir, Selim (Taylor & Francis Ltd., 2021)
The aim of the present study was to evaluate the protective effect of gallic acid (GA) against cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was generated with CDDP (5 mg/kg) intraperitoneally ...
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