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The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation 

Kostakoglu, Ugur; Topcu, Atilla; Atak, Mehtap; Tumkaya, Levent; Mercantepe, Tolga; Uydu, Huseyin Avni (Pergamon-Elsevier Science Ltd, 2020)
Aims: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2.38 million people a year die from respiratory ...

The effect of white tea on serum TNF-alpha/NF-kappa B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats 

Saral, Sinan; Dokumacioglu, Eda; Mercantepe, Tolga; Atak, Mehtap; Cinar, Seda; Saral, Ozlem; Tumkaya, Levent (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)
Objective: Nephrotoxicity is the most important side effect of the antineoplastic drug cisplatin, thereby restricting its use. the aim of this study was to investigate the protective effects of white tea infusions(WT) ...

The Role of Vaccinium Myrtillus in the Prevention of Renal Injury in an Experimental Model of Ruptured Abdominal Aortic Aneurysm 

Ergene, Saban; Hemsinli, Dogus; Karakisi, Sedat Ozan; Mercantepe, Tolga; Tumkaya, Event; Yilmaz, Adnan (Soc Brasil Cirurgia Cardiovasc, 2020)
Objective: To examine the biochemical and histopathological renal effects of ischemia/reperfusion (I/R) injury using a ruptured abdominal aortic aneurysm (RAAA) model in rats and to investigate the potential protective ...

Tea Grape Reduces Abdominal Aortic Occlusion-Induced Lung Injury 

Hemsinli, Dogus; Ergene, Saban; Karakisi, Sedat Ozan; Mercantepe, Tolga; Tumkaya, Levent; Yilmaz, Adnan; Akyilzdiz, Kerimali (Soc Brasil Cirurgia Cardiovasc, 2020)
Introduction: Ischemia-associated mortality caused by aortic cross-clamps, as in ruptured abdominal aorta aneurysm surgeries, and reperfusion following their removal represent some of the main emergency conditions in ...

An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats 

Topcu, Atilla; Balik, Gulsah; Atak, Mehtap; Mercantepe, Tolga; Uydu, Huseyin Avni; Tumkaya, Levent (Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...

Pelvic Radiation-Induced Testicular Damage: An Experimental Study at 1 Gray 

Rakici, Sema Yilmaz; Guzel, Ali Irfan; Tumkaya, Levent; Nalkiran, Hatice Sevim; Mercantepe, Tolga (Taylor & Francis Inc, 2020)
Therapeutic radiation of the pelvic region has been shown to cause damage to testicular germ cells. in this study we aimed to evaluate the effects of a low therapeutic dose of 1 Gy on the induction of cellular and histological ...

Protective effects of amifostine, curcumin and melatonin against cisplatin-induced acute kidney injury (vol 391, pg 915, 2018) 

Mercantepe, Filiz; Mercantepe, Tolga; Topcu, Atilla; Yilmaz, Adnan; Tumkaya, Levent (Springer, 2019)
[No abstract available]

The Effects of Mobile Phone Exposure on Mast Cells in Rat Dura Mater 

Tumkaya, Levent; Kalkan, Yildiray; Gokce, Fatih Mehmet; Erdivanli, Basar; Yilmaz, Adnan; Bahceci, Ilkay; Mercantepe, Tolga (Soc Chilena Anatomia, 2019)
Mobile phone use has increased rapidly. the central nervous system has been shown to be adversely affected by its electromagnetic field (EMF) resulting in headache and sleep disturbances. How the cells make up the CNS and ...

Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats 

Eren, Huseyin; Mercantepe, Tolga; Tumkaya, Levent; Mercantepe, Filiz; Dil, Eyup; Horsanali, Mustafa Ozan; Yilmaz, Adnan (Academic Press Inc Elsevier Science, 2020)
[No abstract available]

The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats 

Mercantepe, Tolga; Topcu, Atilla; Rakici, Sema; Tumkaya, Levent; Yilmaz, Adnan; Mercantepe, Filiz (Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...
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