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The effect of royal jelly on CD3+, CD5+, CD45+ T-cell and CD68+ cell distribution in the colon of rats with acetic acid-induced colitis 

Karaca, T.; Şimşek, N.; Uslu, S.; Kalkan, Yıldıray; Can, I.; Kara, A.; Yörük, M. (Elsevier, 2012)
Background: Traditional medicines and health supplements have historically been used to treat many illnesses but most of them have not been evaluated objectively to prove their efficacy. We have been investigating the ...

Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study 

Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Yılmaz, Adnan (Springer, 2012)
Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ...

Protective effect of curcumin on acute lung injury induced by intestinal ischaemia/reperfusion 

Güzel, Aygül; Kanter, Mehmet; Güzel, Ahmet; Yücel, Ahmet Fikret; Erboğa, Mustafa (Sage Journals, 2013)
The aim of this study is to evaluate the role of curcumin on acute lung injury induced by intestinal ischaemia/reperfusion (I/R). A total of 30 male Wistar albino rats were divided into 3 groups: sham, I/R, and I/R + ...

The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study 

Çiftel, Serpil; Tümkaya, Levent; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Mercantepe, Tolga (Springer, 2024)
Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ...

The investigation of damage in the muscle tissue with the oxidant/antioxidant balance and the extent of postmortem DNA damage in rats 

Öztürk, Cengiz; Şener, Mustafa Talip; Şener, Ebru; Yılmaz, İsmail; Akçay, Fatih; Süleyman, Halis (2013)
The relationship of the extent of DNA damage and certain components of the oxidant/antioxidant balance in rat femoral muscle tissue with the post-mortem intervals was investigated and examined by making direct comparison ...

Comparative analysis of epigallocatechin-3-gallate and TNF-alpha inhibitors in mitigating cisplatin-induced pancreatic damage through oxidative stress and apoptosis pathways 

Çiftel, Enver; Mercantepe, Filiz; Mercantepe, Tolga; Akyıldız, Kerimali; Yılmaz, Adnan; Çiftel, Serpil (Springer, 2024)
Oxidative stress and inflammation caused by cisplatin, which is frequently used in the treatment of many cancers, damage healthy tissues as well as cancer cells. In this study, we aimed to investigate the effect of ...

Dexmedetomidine on the interplay of IL-6 and STAT3 pathways in adrenal gland damage-induced scalding burns in rats 

Çiftel, Serpil; Mercantepe, Filiz; Mercantepe, Tolga; Çiftel, Enver; Klisic, Aleksandra (Springer, 2024)
Scalding burns are a common form of thermal injury that often leads to systemic complications. Pro-inflammatory cytokines like interleukin-6 (IL-6) and the activation of signal transducer and activator of transcription 3 ...

The hepatoprotective effects of camellia sinensis on cisplatin-induced acute liver injury 

Yılmaz, Adnan; Dizman, Fatih; Akyıldız, Kerimali; Mataracı Karakaş, Sibel; Mercantepe, Tolga; Uydu, Hüseyin Avni; Tümkaya, Levent; Öztürk, Köksal (MDPI, 2024)
Acute liver injury is an increasing global health problem. It is a widespread side effect of cisplatin treatment in the clinic and can lead to liver failure if not treated promptly. Previous studies have revealed that green ...

Investigating the hepatic response to orlistat and white tea in rats on a high-fat diet 

Çiftel; Klisic, Aleksandra; Çiftel, Enver; Mercantepe, Tolga; Yılmaz, Adnan; Çiftel, Sedat; Pınarbaş, Esra; Toraman, Merve Nur; Mercantepe, Filiz (MDPI, 2024)
High-fat diets have detrimental health impacts that increase the likelihood of developing obesity and metabolic syndrome. This study aimed to examine the potential antioxidant and anti-inflammatory effects of orlistat and ...

Preventive effects of melatonin and amifostine on irradiated rats with experimental periodontitis 

Yorgancılar, Nur; Köse, Oğuz; Rakıcı, Sema Yılmaz; Mercantepe, Tolga; Akyıldız, Kerimali; Tümkaya, Levent; Yılmaz, Adnan (Springer, 2024)
Background: The aim of this study was to investigate the preventive effects of amifostine and melatonin oxidatively, biochemically and histomorphometrically in rats with radiotherapy-induced experimental periodontitis. ...
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