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Küçük Resim

Protective effects of estrogen and bortezomib in kidney tissue of post-menopausal rats: an ultrastructural study 

Mercantepe, Tolga; Ünal, Deniz; Selli, Jale; Mercantepe, Filiz; Ünal, Bünyamin; Karabıyık, Tuba Nur (Taylor & Francis Ltd, 2016)
Purpose: Symptoms and disorders related to menopause and its associated estrogen deficiency have become a considerable health concern worldwide. Ovarian hormone depletion/estrogen deficiency can be usefully studied using ...
Küçük Resim

Effects of long-term exposure to 900 megahertz electromagnetic field on heart morphology and biochemistry of male adolescent rats 

Kerimoğlu, Gökçen; Mercantepe, Tolga; Erol, Hüseyin Serkan; Turgut, Alpgiray; Kaya, Haydar; Çolakoğlu, Serdar; Odacı, Ersan (Taylor & Francis Ltd, 2016)
The pathological effects of exposure to an electromagnetic field (EMF) during adolescence may be greater than those in adulthood. We investigated the effects of exposure to 900 MHz EMF during adolescence on male adult rats. ...

Morphological and antioxidant impairments in the spinal cord of male offspring rats following exposure to a continuous 900 MHz electromagnetic field during early and mid-adolescence 

Ikinci, Ayse; Mercantepe, Tolga; Unal, Deniz; Erol, Huseyin Serkan; Sahin, Arzu; Aslan, Ali; Odaci, Ersan (Elsevier, 2016)
The effects of devices emitting electromagnetic field (EMF) on human health have become the subject of intense research among scientists due to the rapid increase in their use. Children and adolescents are particularly ...

Evaluation of dose depended protective effect of resveratrol at cisplatin induced ovarian damage 

Tekin, Yeşim Bayoğlu; Çetin, Nihal; Kalkan, Yıldıray; Süleyman, Bahadır; Mercantepe, Tolga; Ural, Ülkü Mete; Güven, Emine Seda Güvendağ (Oxford Univ Press, 2016)
....
Küçük Resim

Apelin-13 activates the hippocampal BDNF/TrkB signaling pathway and suppresses neuroinflammation in male rats with cisplatin-induced cognitive dysfunction 

Saral, Sinan; Topçu, Atilla; Alkanat, Mehmet; Mercantepe, Tolga; Akyıldız, Kerimali; Yıldız, Lamiye; Tümkaya, Levent; Yazıcı, Zihni Açar; Yılmaz, Adnan (Elsevier, 2021)
It has been established that cisplatin causes neuronal damage and cognitive impairment. However, the mechanism is not sufficiently clear. Apelin-13 is an endogenous peptide with strong neuroprotective effects through the ...
Küçük Resim

The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats 

Topçu, Atilla; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Tümkaya, Levent; Yılmaz, Adnan (Taylo & Francis Ltd., 2021)
Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ...
Küçük Resim

The protective role of fosfomycin in lung injury due to oxidative stress and inflammation caused by sepsis 

Yıldız, İlknur Esen; Topçu, Atilla; Bahçeci, İlkay; Arpa, Medeni; Tümkaya, Levent; Mercantepe, Tolga; Batçık, Şule; Yıldız, Yasin (Pergamon-Elsevier Science Ltd., 2021)
Aim: Early and prompt treatment of sepsis by effective antibiotics against susceptible organisms may be lifesaving. However, increased antibiotic resistance and side effects of chemotherapeutic agents limiting their ...
Küçük Resim

The protective effects of topiramate on intestinal injury induced with infrarenal aortic occlusion via oxidative stress and apoptosis 

Pergel, Ahmet; Demiral, Gökhan; Tümkaya, Levent; Mercantepe, Tolga; Özdemir, Ali; Kalcan, Süleyman; Çolakoğlu, Muhammed Kadri; Yılmaz, Adnan; Bedir, Recep; Karakaya, Ahmet (Taylo & Francis Ltd., 2021)
Purpose: Prolonged surgical procedures and some clinical conditions such as surgeries of thoracoabdominal aorta, mesenteric ischemia, cardiopulmonary bypass, strangulated hernias and neonatal necrotizing enterocolitis may ...
Küçük Resim

Periodontitis exacerbates the renal degenerative effects of obesity in rats 

Kurt-Bayrakdar, Sevda; Köse, Oğuz; Altın, Ahmet; Akyıldız, Kerimali; Mercantepe, Tolga; Bostan, Semih Alperen; Köse, Taha Emre; Tümkaya, Levent; Yılmaz, Adnan (Wiley, 2021)
Background/objectives Obesity and periodontitis are systemic subclinical inflammatory diseases with established negative renal effects. The aim of this animal study was to thoroughly investigate the possible effects of ...
Küçük Resim

Protective effect of thymoquinone in preventing trauma-related damage: an experimental study 

Erdivanlı, Başar; Özdemir, Abdullah; Şen, Ahmet; Mercantepe, Tolga; Kazdal, Hızır; Uydu, Hüseyin Avni; Tümkaya, Levent (Taylo & Francis Ltd., 2021)
Background Secondary injury is a potentially modifiable factor of outcome in traumatic brain injury. This study aimed to investigate thymoquinone's effects on trauma-induced neuronal damage. Methods Eighteen adult female ...
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