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Küçük Resim

The protective effects of perindopril against acute kidney damage caused by septic shock 

Kostakoğlu, Uğur; Mercantepe, Tolga; Yılmaz, Hülya Kılıç; Tümkaya, Levent; Batçık, Şule; Pınarbaş, Esra; Uydu, Hüseyin Avni (Springer/Plenum Publishers, 2021)
Acute kidney injury (AKI) resulting from septic shock caused by sepsis is an important health problem encountered at rates of 55-73%. Increasing oxidative stress and inflammation following sepsis is a widely observed ...
Küçük Resim

Protective effect of edaravone against radiation-induced ovarian injury: a histopathological and immunohistochemical evaluation in an experimental rat model 

Ural, Ülkü Mete; Gürlek, Beril; Alver, Ahmet (Springer Heidelberg, 2021)
Purpose We aimed to evaluate the protective effect of edaravone on radiation-induced ovarian damage in an experimental rat model. Methods Thirty-two Wistar albino female rats were randomly divided into four groups. Group ...
Küçük Resim

The effect of imatinib administered in the prenatal period on testis development in rats 

Suzan, Zehra Topal; Tümkaya, Levent; Mercantepe, Tolga; Atak, Muhammed; Uydu, Hüseyin Avni (Sage Publications Ltd, 2021)
Background: the purpose of this study was to examine the effects of exposure to imatinib in the prenatal period on testis development in rats. Methods: Although all the study groups received intraperitoneal imatinib on ...
Küçük Resim

The role of antioxidant activity in the prevention and treatment of infertility caused by cisplatin in rats 

Aksoy, Ayşe Nur; Kücür, Suna Kabil; Batmaz, Gonca; Gözükara, İlay; Aksoy, Mehmet; Kurt, Nezahat; Mammadov, Renad (Karger, 2015)
Background/Aims:To investigate the importance of antioxidant activity in infertility caused by cisplatin in rats. Methods: Rats in cisplatin control (CG), Vitamin E+cisplatin (ECG), Vitamin C + cisplatin (CCG), Hippophae ...
Küçük Resim

The effects of thiamine and thiamine pyrophosphate on alcohol-induced hepatic damage biomarkers in rats 

Yılmaz, İsmayil; Demiryılmaz, İsmail; Turan, Mehmet İbrahim; Çetin, Nihal; Gül, Mehmet Ali; Süleyman, Halis (Verduci Publisher, 2015)
OBJECTIVE: This study examined the effects of thiamine and thiamine pyrophosphate on oxidative damage developing in association with hepatic injury caused by alcohol toxicity in rats and on hepatic injury markers. MATERIALS ...
Küçük Resim

Can prenatal exposure to a 900 MHz electromagnetic field affect the morphology of the spleen and thymus, and alter biomarkers of oxidative damage in 21-day-old male rats? 

Hancı, Hatice; Türedi, Sibel; Topal, Zehra Suzan; Mercantepe, Tolga; Bozkurt, İlyas; Kaya, Haydar; Ersöz, Şafak; Ünal, Bünyamin; Odacı, Ersan (Taylor & Francis Ltd, 2015)
We investigated the effects of a 900 Megahertz (MHz) electromagnetic field (EMF), applied during the prenatal period, on the spleen and thymus of 21-day-old male rat pups. Pregnant Sprague-Dawley rats were divided into ...
Küçük Resim

Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats 

Yücel, Ahmet Fikret; Pergel, Ahmet; Aydın, İbrahim; Alaçam, Hasan; Karabıçak, İlhan; Kesicioğlu, Tuğrul; Tümkaya, Levent; Kalkan, Yıldıray; Arslan, Zakir; Şehitoğlu, İbrahim; Şahin, Dursun Ali (E-Century Publishing Corp, 2015)
This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ...

The effect of controlled reperfusion in the prevention of infertility caused by ischemia induced in the contralateral ovary in rats with unilateral ovariectomy 

Aksoy, Ayşe Nur; Aydın, Fatma; Yılmaz, Emsal Pınar Topdağı; Batmaz, Gonca; Süleyman, Bahadır (Karger, 2015)
Background/Aims: To investigate the effectiveness of controlled reperfusion (CR) on ovarian tissue malondialdehyde, total glutathione and 8-hydroxyguanine levels and infertility rates in a rat model of induced ischemia-reperfusion ...
Küçük Resim

Chondroprotective effects of a new glucosamine combination in rats: Gene expression, biochemical and histopathological evaluation 

Üçüncü, Yılmaz; Çelik, Nuray; Öztürk, Cengiz; Türkoğlu, Murat; Çetin, Nihal; Koçkara, Nizamettin; Şener, Ebru; Dündar, Cihat; Arslan, Aynur; Doğan, Hasan; Kurt, Nezahat; Süleyman, Halis (Pergamon-Elsevier Science Ltd, 2015)
Aims: This study investigates the effect of a new combination of glucosamine hydrochloride, chondroitin sulfate, methylsulfonylmethane, Harpagophytum procumbens root extract (standardized to 3% harpagoside) and bromelain ...
Küçük Resim

Effect of sugammadex on rocuronium induced changes in pancreatic mast cells 

Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Altuner, Durdu; Yılmaz, Adnan; Erdivanlı, Başar; Bedir, Recep; Yalçın, Alper; Turan, Alparslan (Sage Publications Inc, 2015)
Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ...
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