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Toplam kayıt 29, listelenen: 21-29
Radioprotective effects of dexmedetomidine on X-ray-induced testicular damage
(Verduci Publisher, 2023)
OBJECTIVE: Approximately 70%
of cancer patients require radiotherapy. However, despite its effectiveness in the treatment of
cancer, radiotherapy can also affect and damage
surrounding healthy tissues in addition to ...
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats
(Taylor & Francis Ltd., 2023)
The aim of this study was to determine the possible therapeutic effect of chlorogenic acid (CGA) on cisplatin (CDDP)-induced ovarian damage in rats. Rats were first exposed to CDDP (5 mg/kg) and then treated CGA (1.5 and ...
The therapeutic effect of silibinin against 5-fluorouracil-induced ovarian toxicity in rats
(Wiley, 2023)
5-Fluorouracil (5-FU) is a fluoropyrimidine group antineoplastic drug with antimetabolite properties and ovotoxicity is one of the most important side effects. Silibinin (SLB) is a natural compound that is used worldwide ...
Syringic acid ameliorates ischemia/reperfusion-induced testicular injury in rats via suppressing of HMGB1/NF-kappa B axis and endoplasmic reticulum stress
(Springer, 2023)
PurposeTo investigate the possible protective role of syringic acid on torsion/detorsion-induced testicular injury using biochemical and histopathological approaches for the first time.MethodsA total of 24 rats were divided ...
An investigation of the protective effect of rhododendron luteum extract on cisplatin-induced DNA damage and nephrotoxicity and biochemical parameters in rats
(University of Agriculture, 2023)
The nephrotoxicity mechanisms caused by cisplatin (CP), which is used in the treatment of different types of cancer, include several processes, such as DNA damage, apoptosis, inflammation, and oxidative stress. This study ...
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
(Taylor & Francis Ltd., 2023)
Background: The objective of this study was to investigate the effect of dexmedetomidine
(Dex), a sedative drug with little or no depressant effect on respiratory centers, on
secondary injury in rat brain tissue by means ...
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
(Karger, 2023)
Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ...
N-acetylcysteine ameliorates 5-fluorouracil-induced ovarian injury in rats
(Marmara Üniversitesi, 2023)
Objective: Although 5-fluorouracil (5-FU) is one of the most commonly used chemotherapeutics worldwide, it has been shown that 5-FU administration can cause reproductive toxicity in recent years. N-acetylcysteine (NAC) is ...
Royal jelly can diminish secondary neuronal damage after experimental spinal cord injury in rabbits
(Elsevier, 2012)
The aim of this experimental study was to investigate the neuroprotective effect of Royal jelly (RJ) on traumatic spinal cord injury (SCI). Twenty-one New Zealand male rabbits, weighing between 2.5 and 3.0. kg were divided ...