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The protective effects of angiotensin-converting enzyme inhibitor against cecal ligation and puncture-induced sepsis via oxidative stress and inflammation

Kostakoglu, Ugur; Topcu, Atilla; Atak, Mehtap; Tumkaya, Levent; Mercantepe, Tolga; Uydu, Huseyin Avni (Pergamon-Elsevier Science Ltd, 2020)

Aims: Sepsis is a severe public health problem affecting millions of individuals, with global mortality rates caused by lower respiratory tract infections are approximately 2.38 million people a year die from respiratory ...

Tea Grape Reduces Abdominal Aortic Occlusion-Induced Lung Injury

Hemsinli, Dogus; Ergene, Saban; Karakisi, Sedat Ozan; Mercantepe, Tolga; Tumkaya, Levent; Yilmaz, Adnan; Akyilzdiz, Kerimali (Soc Brasil Cirurgia Cardiovasc, 2020)

Introduction: Ischemia-associated mortality caused by aortic cross-clamps, as in ruptured abdominal aorta aneurysm surgeries, and reperfusion following their removal represent some of the main emergency conditions in ...

Pelvic Radiation-Induced Testicular Damage: An Experimental Study at 1 Gray

Rakici, Sema Yilmaz; Guzel, Ali Irfan; Tumkaya, Levent; Nalkiran, Hatice Sevim; Mercantepe, Tolga (Taylor & Francis Inc, 2020)

Therapeutic radiation of the pelvic region has been shown to cause damage to testicular germ cells. in this study we aimed to evaluate the effects of a low therapeutic dose of 1 Gy on the induction of cellular and histological ...

Evaluation of the protective effects of amifostine and melatonin against cisplatin induced testis injury via oxidative stress and apoptosis in rats

Eren, Huseyin; Mercantepe, Tolga; Tumkaya, Levent; Mercantepe, Filiz; Dil, Eyup; Horsanali, Mustafa Ozan; Yilmaz, Adnan (Academic Press Inc Elsevier Science, 2020)

[No abstract available]

Protective effects of nebivolol on ovarian ischemia-reperfusion injury in rat

Colak, Sabri; Gurlek, Beril; Topcu, Atilla; Tumkaya, Levent; Mercantepe, Tolga; Yilmaz, Adnan (Wiley, 2020)

Aim Ovarian torsion is a common gynecological emergency of reproductive ages, occurring at rates of 2.7-7.4%. This study aimed to evaluate the antioxidant effects of Nebivolol (NEB) and histopathological changes in ...

The protective effects of adalimumab on intestinal injury induced with infrarenal aortic occlusion

Pergel, Ahmet; Tumkaya, Levent; Demiral, Gokhan; Colakoglu, Muhammet Kadri; Kalcan, Suleyman; Ozdemir, Ali; Yilmaz, Adnan (Turkish Assoc Trauma Emergency Surgery, 2020)

BACKGROUND: the present study aims to observe the effects of ischemia-reperfusion (IR) on small intestines at a molecular level and to prospectively assess the potential preventive role of adalimumab (ADA) and antioxidants. ...