Ara
Toplam kayıt 7, listelenen: 1-7
Synthesis and study of alpha-glucosidase inhibitory, antimicrobial and antioxidant activities of some benzimidazole derivatives containing triazole, thiadiazole, oxadiazole, and morpholine rings
(Springer, 2015)
A new series of 2-(4-bromobenzyl)- and 2-(4-fluorobenzyl)-1H-benzimidazole derivatives containing 1,2,4-triazole, 1,3,4-thiadiazole, 1,3,4-oxadiazole, and morpholine rings has been synthesized. the structures of the newly ...
Microwave-assisted and conventional synthesis of novel antimicrobial 1,2,4-triazole derivatives containing nalidixic acid skeleton
(Walter de Gruyter Gmbh, 2016)
Carbothioamides 4a,b, obtained from nalidixic acid, were converted to the corresponding 1,3-thiazolidine derivatives 5a,b by cyclocondensation with 2-bromo-1-(4-chlorophenyl) ethanone. Treatment of 4a,b with base afforded ...
Microwave assisted synthesis and antimicrobial activity evaluation of new heterofunctionalized norfloxacine derivatives
(Bentham Science Publ Ltd, 2016)
The synthesis of new hybrid compounds containing several heterocyclic groups namely norfloxacine, 1,2,4-triazole, 1,3,4-oxadiazole, piperazine, morpholine, thiomorpholine, 1,3,4-thiadiazole etc. was performed by conventional ...
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
(Bentham Science Publ Ltd, 2016)
Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. the acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ...
Structure-based hybridization, microwave prompted synthesis and biological evaluation of novel 4-(2-fluoro-4-nitrophenyl)morpholine derivatives
(Bentham Science Publ Ltd, 2018)
1,3,4-oxadiazole-2-thiole 6 was obtained from 4-(2-fluoro-4-nitrophenyl)morpholine (2) by the reduction of its nitro group and the sequential treatment of the resulting amine with ethyl bro-moacetate, hydrazine hydrate, ...
Piperazine-azole-fluoroquinolone hybrids: Conventional and microwave irradiated synthesis, biological activity screening and molecular docking studies
(Academic Press Inc Elsevier Science, 2019)
A series of new 1,2,4-triazole and 1,3,4-oxadiazole derivatives was obtained via several steps sequential reactions of phenyl piperazine. Then, these compounds were converted to the corresponding fluoroquinolone hybrids ...
Synthesis of eperezolid-like molecules and evaluation of their antimicrobial activities
(Springer Link, 2012)
3-Fluoro-4-(4-phenylpiperazin-l-yl)aniline (II) prepared from 3,4-difluoro nitrobenzene was converted to the corresponding Schiff bases (III) and (IV) by treatment with 4-methoxybenzaldehyde and indol-3-carbaldehyde, ...