Browsing Fakülteler by Author "Bıyıklıoğlu, Zekeriya"
Now showing items 1-8 of 8
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Design, synthesis and biological evaluation of water soluble and non-aggregated silicon phthalocyanines, naphthalocyanines against A549, SNU-398, SK-MEL128, DU-145, BT-20 and HFC cell lines as potential anticancer agents
Keleş, Turgut; Barut, Burak; Özel, Arzu; Bıyıklıoğlu, Zekeriya (Elsevier, 2021)Cancer has become an important public problem in worldwide since cancer incidence and mortality are growing rapidly. In this study, water soluble and non-aggregated silicon (IV) phthalocyanines and naphthalocyanines ... -
Microwave-assisted synthesis and characterization of novel metal-free and metallophthalocyanines containing four 14-membered tetraaza macrocycles
Bıyıklıoğlu, Zekeriya; Kantekin, Halit; Özil, Musa (Elsevier, 2007)The novel tetrasubstituted metal-free phthalocyanine (6) and metallophthalocyanines (7, 8) bearing four 14-membered tetraaza macrocycles moieties on peripheral positions have been synthesized by cyclotetramerization reaction ... -
Peripheral or nonperipheral tetra-[4-(9H-carbazol-9-yl)phenoxy] substituted cobalt(II), manganese(III) phthalocyanines: Synthesis, acetylcholinesterase, butyrylcholinesterase, and α-glucosidase inhibitory effects and anticancer activities
Barut, Burak; Keleş, Turgut; Bıyıklıoğlu, Zekeriya; Yalçın, Can Özgür (Wiley, 2020)In this work, peripheral or nonperipheral tetra-[4-(9H-carbazol-9-yl)phenoxy] substituted cobalt(II), manganese (III) phthalocyanines were synthesized for the first time. Their acetylcholinesterase from Electrophorus ... -
Substituted phthalocyanines and their electropolymerization properties
Bayrak, Rıza; Akçay, Hakkı Türker; Bıyıklıoğlu, Zekeriya; Değirmencioğlu, İsmail (Elsevier Science Sa, 2016)In this study, new metal-free and metallo-phthalocyanine complexes (Co, TiO) were synthesized using a piperazine-substituted phthalonitrile derivative. All proposed structures were supported by instrumental methods. ... -
Synthesis and acetylcholinesterase enzyme inhibition properties of axially disubstituted silicon phthalocyanines and their quaternized derivatives
Bıyıklıoğlu, Zekeriya; Keleş, Turgut; Şahin, Hüseyin (Elsevier, 2022)In this paper, axial 1,3-bis[4-(4-acetylpiperazin-1-yl)phenoxy]propanoxy and {2-[4-(4-acetylpiperazin-1-yl)phenoxy]ethoxy}ethoxy groups substituted silicon(IV) phthalocyanines ( PP-D-Si, PP-OH2-Si) and their quaternized ... -
Synthesis and in vitro alpha-glucosidase and cholinesterases inhibitory actions of watersoluble metallophthalocyanines bearing ({6-[3-(diethylamino)phenoxy]hexyl}oxy groups
Keleş, Turgut; Bıyıklıoğlu, Zekeriya; Akkaya, Didem; Özel, Arzu; Barut, Burak (Scientific Technical Research Council Turkey, TÜBİTAK, 2022)In this paper, we have prepared peripherally tetra-({6-[3-(diethylamino)phenoxy]hexyl}oxy substituted cobalt(II), copper(II), manganese(III) phthalocyanines (3, 4, 5) and their water-soluble derivatives (3a, 4a, 5a). Then, ... -
Synthesis and in vitro α-glucosidase and cholinesterases inhibitory actions of water-soluble metallophthalocyanines bearing ({6-[3-(diethylamino)phenoxy]hexyl}oxy groups
Keleş, Turgut; Bıyıklıoğlu, Zekeriya; Akkaya, Didem; Özel, Arzu; Barut, Burak (TUBITAK, 2022)In this paper, we have prepared peripherally tetra-({6-[3-(diethylamino)phenoxy]hexyl}oxy substituted cobalt(II), copper(II), manganese(III) phthalocyanines (3, 4, 5) and their water-soluble derivatives (3a, 4a, 5a). Then, ... -
Synthesis of water-soluble BODIPY dyes and investigation of their DNA interaction properties and cytotoxicity/phototoxicity
Keleş, Turgut; Barut, Burak; Yıldırım, Sercan; Yalçın, Can Özgür; Bıyıklıoğlu, Zekeriya (Wiley, 2021)In this study, water-soluble BODIPY dyes (BDPY-4, BDPY-5) bearing dimethylamino and diethylamino groups were synthesized for the first time. The DNA interaction and nuclease effect of two water-soluble BODIPY dyes were ...