Yazar "RTEÜ, Sağlık Hizmetleri Meslek Yüksekokulu, Tıbbi Hizmetler ve Teknikler Bölümü" için Meslek Yüksekokulları listeleme
-
Alpha-pinene neutralizes cisplatin-induced reproductive toxicity in male rats through activation of Nrf2 pathway
Demir, Selim; Menteşe, Ahmet; Türkmen Usta, Zeynep; Türkmen Alemdar, Nihal; Ayazoğlu Demir, Elif; Aliyazıcıoğlu, Yüksel (Springer, 2023)Purpose Testicular toxicity is one of the most important side efects of cisplatin (CP) therapy. Alpha-pinene (AP) is a naturally occurring monoterpene with antioxidant character in plants. Here, we aimed to evaluate the ... -
Ameliorative effect of gallic acid on cisplatin-induced ovarian toxicity in rats
Ayazoğlu Demir, Elif; Menteşe, Ahmet; Livaoğlu, Ayten; Türkmen Alemdar, Nihal; Demir, Selim (Taylor & Francis Ltd., 2021)The aim of the present study was to evaluate the protective effect of gallic acid (GA) against cisplatin (CDDP)-induced ovarian toxicity, for the first time. The ovarian damage was generated with CDDP (5 mg/kg) intraperitoneally ... -
The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS
Turan, İbrahim; Canbolat, Deniz; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Türkmen Alemdar, Nihal; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (Elsevier, 2023)Cisplatin (CDDP) is an important chemotherapeutic agent, accumulation of which in kidney tissue causes nephrotoxicity and renal failure. The aim of this study was to evaluate, for the first time in the literature, the ... -
Anxiety, motivation, stress levels and associated factors among university students in the COVID-19 pandemic
Uzun Şahin, Ceyda; Aydın, Merve; Kulakaç, Nurşen (2022)BACKGROUND/AIMS: The global coronavirus disease (COVID-19) pandemic affects society seriously in terms of psychosocial aspects, but this effect is more intense on some specific population groups. University students are ... -
Arbutin abrogates testicular ischemia/reperfusion injury in rats through repression of inflammation and ER stress
Demir, Elif Ayazoğlu; Demir, Selim; Kazaz, İlke Onur; Küçük, Hatice; Alemdar, Nihal Türkmen; Büyük, Ali; Menteşe, Ahmet; Aliyazıcıoğlu, Yüksel (Elsevier, 2023)The aim of this study was to investigate the effects of arbutin (ARB) administration on oxidative stress, inflammation, endoplasmic reticulum (ER) stress and apoptosis in an experimental testicular torsion/detorsion ... -
Bread consumption-induced heavy metal exposures and health risk assessment of pregnant women: Turkey
Köse, Burcu Genç; Pekmezci, Hilal; Başaran, Burhan (Springer, 2023)Affordable, nutritious, and easily available bread has a significant place in the nutrition of pregnant women. This study aims to determine bread consumption-induced heavy metal exposure in pregnant women with different ... -
Chlorogenic acid ameliorates torsion/detorsion-induced testicular injury via decreasing endoplasmic reticulum stress
Kazaz, İlke Onur; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Türkmen Alemdar, Nihal; Doğan, Sedanur Yılmaz; Bostan, Serdar; Menteşe, Ahmet (Elsevier, 2022)Backround Testicular torsion (TT) is an urological emergency situation especially in adolescents and young men. The main pathophysiology of testicular torsion/detorsion (T/D) is ischemia-reperfusion (I/R) injury. I/R ... -
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats
Demir, Elif Ayazoğlu; Menteşe, Ahmet; Livaoğlu, Ayten; Alemdar, Nihal Türkmen; Aliyazıcıoğlu, Yüksel; Demir, Selim (Taylor & Francis Ltd., 2023)The aim of this study was to determine the possible therapeutic effect of chlorogenic acid (CGA) on cisplatin (CDDP)-induced ovarian damage in rats. Rats were first exposed to CDDP (5 mg/kg) and then treated CGA (1.5 and ... -
Comparison of preoperative and postoperative sexual dysfunction in male patients with lumbar disc herniation
Uzun Şahin, Ceyda; Aydın, Merve; Kalkışım, Selçuk; Şahin, Handan; Civil Arslan, Filiz (Turkish Neurosurgical Society, 2022)AIM: To compare preoperative and postoperative sexual dysfunction in male patients diagnosed with lumbar disc herniation (LDH). MATERIAL and METHODS: This study was conducted in a single group with a pretest???posttest ... -
COVID-19 vaccine acceptance, trust in vaccine, anxiety levels, and related factors in Turkish society
Aydın, Merve; Kulakaç, Nurşen; Uzun Şahin, Ceyda (Cambridge University Press, 2023)Background: Vaccine acceptance and trust in vaccines pose a complex process affected by many factors. The present study was conducted to determine coronavirus disease 2019 (COVID-19) vaccine acceptance, trust in vaccines, ... -
Determination of the factors affecting the COVID-19 knowledge levels and the status of being diagnosed with covıd-19 in healthcare employees struggling with pandemic
Uzun Şahin, Ceyda; Kulakaç, Nurşen (Gümüşhane Üniversitesi, 2022)The present study was conducted to determine of the factors affecting the COVID-19 knowledge levels and the status of being diagnosed with COVID-19 in healthcare employees struggling with the pandemic. This study, which ... -
Disease and treatment experiences of COVID-19 patients: A qualitative study
Şahin, Ceyda Uzun; Aydın, Merve; Usta, Abdullah; Sakin, Mustafa (Galenos Yayıncılık, 2021)BACKGROUND/AIMS The study aimed to explore the perceptions of hospitalized COVID-19 patients' experiences regarding the disease and treatment process. MATERIAL and METHODS The study was carried out as qualitative ... -
Earthquake knowledge level and sustainable earthquake awareness of university students
Bayraktar, Demet Turan; Çol, Bahar Kefeli; Başaran, Ayşe Gümüşler; Köse, Burcu Genç (Springer, 2024)Health professionals have always had essential duties in earthquake events experienced from the past to the present. Possible earthquake expectations make sustainable earthquake awareness and attitudes of students, who are ... -
Effect of chrysin on endoplasmic reticulum stress in a rat model of testicular torsion
Kazaz, İlke Onur; Demir, Selim; Kerimoğlu, Gökçen; Çolak, Fatih; Alemdar, Nihal Türkmen; Akman, Ahmet Uğur; Çeküç, Ozan Can; Menteşe, Ahmet (Taylor & Francis Ltd., 2021)Background The purpose of this study was to evaluate the possible therapeutic effect of chrysin (CHS) on testicular torsion/detorsion (T/D) injury in vivo through the mechanisms of oxidative stress and endoplasmic reticulum ... -
The effect of rosa pimpinellifolia extract on the proliferation of human tumor cells
Demir, Elif Ayazoğlu; Demir, Selim; Türkmen, Nihal; Turan, İbrahim (Kahramanmaras Sutcu Imam University, 2021)The aim of this study was to evaluate the antioxidant properties of R. pimpinellifolia and its cytotoxic effect against human colon (WiDr), liver (HepG2) and lung (A549) cancer cells compared with a normal fibroblast (BJ) ... -
The effects of foot reflexology upon pain, anxiety, and patient satisfaction among patients having undergone open-heart surgery
Şahin, Ceyda Uzun; Çilingir, Dilek (Ondokuz Mayis Universitesi, 2022)This interventional study was conducted to analyze the effects of foot reflexology intervention upon patients having undergone an open-heart surgery on their pain, anxiety, and satisfaction level. This research was conducted ... -
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway
Demir, Selim; Menteşe, Ahmet; Küçük, Hatice; Yuluğ, Esin; Alemdar, Nihal Türkmen; Demir, Elif Ayazoğlu; Aliyazıcıoğlu, Yüksel (Taylor & Francis Ltd., 2023)Although cisplatin (CDDP) is an antineoplastic drug widely used for the treatment of various tumors, its toxicity on the reproductive system is a concern for patients. Ethyl pyruvate (EP) possesses potent antioxidant and ... -
Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
Ayazoğlu Demir, Elif; Menteşe, Ahmet; Yılmaz, Zeynep Sağnak; Türkmen Alemdar, Nihal; Demir, Selim; Aliyazıcıoğlu, Yüksel (Elsevier, 2023)Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although cisplatin (CP) is widely used in chemotherapy, its toxicity in healthy tissues, including ovotoxicity, is an insurmountable problem. ... -
Experiences and psychosocial difficulties of frontline health care workers struggling with Covid-19 in Turkey: A qualitative study
Uzun Şahin, Ceyda; Aydın, Merve; Usta, Abdullah; Sakin, Mustafa (İstanbul University, 2022)AIM: This study was performed to explore the experiences and the psychosocial difficulties faced by nurses and physicians involved in the treatment and care for COVID-19 adult patients in the intensive care unit. METHOD: ... -
Experimental models to study immune dysfunction in the pathogenesis of Parkinson’s disease
Saponjic, Jasna; Mejías, Rebeca; Nikolovski, Neda; Dragic, Milorad; Çanak, Asuman; Papoutsopoulou, Stamatia; Gürsoy-Özdemir, Yasemin; Fladmark, Kari E.; Ntavaroukas, Panagiotis; Bayar Muluk, Nuray; Zeljkovic Jovanovic, Milica; Fontán-Lozano, Ángela; Comi, Cristoforo; Marino, Franca (MDPI, 2024)Parkinson’s disease (PD) is a chronic, age-related, progressive multisystem disease associated with neuroinflammation and immune dysfunction. This review discusses the methodological approaches used to study the changes ...