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Chlorogenic acid ameliorates torsion/detorsion-induced testicular injury via decreasing endoplasmic reticulum stress
(Elsevier, 2022)
Backround
Testicular torsion (TT) is an urological emergency situation especially in adolescents and young men. The main pathophysiology of testicular torsion/detorsion (T/D) is ischemia-reperfusion (I/R) injury. I/R ...
Vanillic acid abrogates cisplatin-induced ovotoxicity through activating Nrf2 pathway
(Elsevier, 2023)
Although cisplatin (CDDP) is an effective anticancer agent, the ovotoxicity that can occur in female patients limits its use. Oxidative stress (OS) and inflammation are known to contribute to CDDP-induced ovotoxicity. ...
Arbutin abrogates testicular ischemia/reperfusion injury in rats through repression of inflammation and ER stress
(Elsevier, 2023)
The aim of this study was to investigate the effects of arbutin (ARB) administration on oxidative stress, inflammation, endoplasmic reticulum (ER) stress and apoptosis in an experimental testicular torsion/detorsion ...