dc.contributor.author | Erdoğan, T. | |
dc.contributor.author | Çetin, M. | |
dc.contributor.author | Kocaman, S.A. | |
dc.contributor.author | Durakoğlugil, M.E. | |
dc.contributor.author | Çanga, A. | |
dc.contributor.author | Çiçek, Y. | |
dc.contributor.author | Gül, M. | |
dc.date.accessioned | 2020-12-19T20:05:53Z | |
dc.date.available | 2020-12-19T20:05:53Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1307-671X | |
dc.identifier.uri | https://hdl.handle.net/11436/3498 | |
dc.description.abstract | Aim: To investigate the relationship of various hematological and biochemical parameters besides the cardiac enzymes with 30-day outcomes in patients with successfully restored coronary TIMI-3 flow by primary percutaneous coronary intervention (p-PCI). Materials and methods: Two hundred patients with ST elevation myocardial infarction (STEMI), with no history of prior myocardial infarction (MI), who underwent p-PCI and had TIMI-3 flow, were enrolled, consecutively. The primary endpoint of the study was defined as the composite of death, fatal and non-fatal MI, target vessel revascularization and cerebrovascular event. Results: Only ALT concentration (OR: 1.010, 95% CI: 1.003-1.018, P = 0.008), monocyte count (OR: 1.002, 95% CI: 1.001 - 1.004, P = 0.005), hypertension (OR: 3.010, 95% CI: 1.081 - 8.384, p = 0.035) and lower LVEF (OR: 0.926, 95% CI: 0.875 - 0.981, P = 0.008) were independent predictors of primary endpoint in multivariate logistic regression analysis. Conclusion: We found that elevated liver enzymes as determined by serum Alanine aminotransferase levels and monocyte count as well as hypertension and lower LVEF independently predicted 30-day outcomes in patients with successfully restored coronary flow by p-PCI. These parameters may provide new aspects, to identify the pathophysiology and prognosis of acute vascular events, which in turn may facilitate discovery of new treatment modalities. © 2012 Düzce Medical Journal. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Duzce University Medical School | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Alanine aminotransferase | en_US |
dc.subject | Liver enzymes | en_US |
dc.subject | Major adverse cardiac events | en_US |
dc.subject | Monocyte count | en_US |
dc.subject | Primary PCI | en_US |
dc.subject | STEMI | en_US |
dc.title | Alanine aminotransferase levels and monocyte count independently predict 30-day outcomes in st-elevation myocardial infarction patients with successfully restored coronary TIMI-3 flow by primary percutaneous coronary intervention [Alanin aminotransferaz düzeyleri ve monosit sayısı primer perkutan koroner girişim ile başarılı TIMI-3 koroner akım sağlanan ST yükselmeli miyokard infarktüsünde 30 Günlük sonuçları bağımsız olarak öngörür] | en_US |
dc.title.alternative | Alanin aminotransferaz düzeyleri ve monosit sayısı primer perkutan koroner girişim ile başarılı TIMI-3 koroner akım sağlanan ST yükselmeli miyokard infarktüsünde 30 Günlük sonuçları bağımsız olarak öngörür | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ | en_US |
dc.identifier.volume | 16 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 29 | en_US |
dc.identifier.endpage | 34 | en_US |
dc.relation.journal | Duzce Medical Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |