dc.contributor.author | Demircioğlu, Fatih | |
dc.contributor.author | Pak, Yücel | |
dc.contributor.author | Akmansu, Müge | |
dc.contributor.author | Bora, Hüseyin | |
dc.date.accessioned | 2020-12-19T20:05:59Z | |
dc.date.available | 2020-12-19T20:05:59Z | |
dc.date.issued | 2013 | |
dc.identifier.citation | Demircioglu, F., Pak, Y., Akmansu, M., Bora, H., (2013).The Relationship Between Hormone Receptor Status and C-erbB-2 Level with Treatment Results of 640 Breast Cancer Patients.Gazi Medical Journal, 24(3), 74-77.https://doi.org/10.12996/gmj.2013.21 | |
dc.identifier.issn | 2147-2092 | |
dc.identifier.uri | https://doi.org/10.12996/gmj.2013.21 | |
dc.identifier.uri | https://hdl.handle.net/11436/3512 | |
dc.description.abstract | Objective: In this study the relevant factors that effects the treatment outcomes of patients like hormone receptor and c-erbB-2 was established. Methods: The overall and disease-free survival rates were evaluated in 640 breast cancer patients. The mean follow-up was 59,1 months. Overall and disease-free survival rates found by Kaplan-Meier method at SPSS version 16.0. Log-Rank test evaluated the prognostic factors impact. Results: In ER (+) and (-) patients 5 year overall survival rates was 85,7%, 71,2% (p<0,001), disease free survival rates was 79,9%, 63,7% (p<0,001) respectively; in PR (+) and (-) patients 5 year overall survival rates was 85,6%, 71,6% (p<0,001), disease free survival rates was 79,6%, 64,3% (p<0,001) respectively. ER and PR positivity were significantly increased overall and disease-free survival. In c-erbB-2 over-expression 5 year overall survival rates was 76,4%, 85,3% (p=0,002), disease free survival rates was 69,7%, 79,1% (p=0,012) according to (-) patients. The worst prognosis had shown in ER (-), PR (-), cerbB- 2 (+) patients. Conclusion: ER, PR and c-erbB-2 levels have great importance in breast cancer and must be well considered in patients follow-up. © Copyright 2013 by Gazi University Medical Faculty. | en_US |
dc.language.iso | tur | en_US |
dc.publisher | Gazi Üniversitesi Tıp Fakültesi | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Breast neoplasm | en_US |
dc.subject | C-erbB-2 | en_US |
dc.subject | Hormone receptor status | en_US |
dc.title | The relationship between hormone receptor status and C-erbB-2 level with treatment results of 640 breast cancer patients | en_US |
dc.title.alternative | Meme kanserli 640 hastada hormon reseptör durumu ve C-erbB-2 düzeyi ile tedavi sonuçlari arasi iliski | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Demircioğlu, Fatih | |
dc.identifier.doi | 10.12996/gmj.2013.21 | |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 3 | en_US |
dc.relation.journal | Gazi Medical Journal | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |