A retrospective study on the effects of diabetes mellitus on perioperative fibrinogen and bleeding amount in coronary artery bypass surgery patients

Abstract

Aim: In this study, the effects of changes in the coagulation system of diabetic patients that undergo heart surgery on postoperative bleeding amount and complications was investigated. Material and Methods: A total of 106 patients (35 females, 71 males) were retrospectively examined in the study. Patients were divided into two groups: diabetic (Group D, n = 47) and non-diabetic (Group C, n = 59). Preoperative and postoperative hematologic values, postoperative bleeding, and transfusion amounts of all groups were recorded. Results: Preoperative and postoperative fibrinogen and C-reactive protein (CRP) values in Group D were significantly higher compared to those in Group C (p< 0.05 and p< 0.01, respectively). Postoperative bleeding amount, erythrocyte, and fibrinogen transfusion need were found to be significantly lower in Group D compared to Group C (p = 0.04, p = 0.01, and p< 0.001, respectively). Conclusion: Diabetic patients had decreased amount ofpostoperative bleeding, possibly due to a thrombotic tendency caused by chronic inflammation related to diabetes mellitus.