dc.contributor.author | Kocabaş, Umut | |
dc.contributor.author | Kıvrak, Tarık | |
dc.contributor.author | Öztekin, Gülsüm Meral Öztekin | |
dc.contributor.author | Tanık, Veysel Ozan | |
dc.contributor.author | Özdemir, İbrahim | |
dc.contributor.author | Tanık, Veysel Ozan | |
dc.contributor.author | Kaya, Ersin | |
dc.contributor.author | Yüce, Elif İlkay | |
dc.contributor.author | Demir, Fulya Avcı | |
dc.contributor.author | Doğduş, Mustafa | |
dc.contributor.author | Altınsoy, Meltem | |
dc.contributor.author | Üstündağ, Songül | |
dc.contributor.author | Özyurtlu, Ferhat | |
dc.contributor.author | Karagöz, Uğur | |
dc.contributor.author | Karakuş, Alper | |
dc.contributor.author | Urgun, Örsan Deniz | |
dc.contributor.author | Sinan, Ümit Yaşar | |
dc.contributor.author | Mutlu, İnan | |
dc.contributor.author | Şen, Taner | |
dc.contributor.author | Astarcıoğlu, Mehmet Ali | |
dc.contributor.author | Kınık, Mustafa | |
dc.contributor.author | Tok, Özge Özden | |
dc.contributor.author | Uygur, Begüm | |
dc.contributor.author | Yeni, Mehtap | |
dc.contributor.author | Alan, Bahadır | |
dc.contributor.author | Dalgıç, Onur | |
dc.contributor.author | Sarıtürk, Çağla | |
dc.contributor.author | Altay, Hakan | |
dc.contributor.author | Pehlivanoğlu, Seçkin | |
dc.date.accessioned | 2020-12-19T20:42:32Z | |
dc.date.available | 2020-12-19T20:42:32Z | |
dc.date.issued | 2020 | |
dc.identifier.citation | Kocabaş, U., Kıvrak, T., Öztekin, GMY., Tanık, VO., Özdemir, I., Kaya, E. (2020). Adherence to guideline-directed medical and device Therapy in outpAtients with heart failure with reduced ejection fraction: the ATA study. The Anatolian Journal of Cardiology, 24(1), 32-40. | en_US |
dc.identifier.issn | 2149-2263 | |
dc.identifier.issn | 2149-2271 | |
dc.identifier.uri | https://doi.org/10.14744/AnatolJCardiol.2020.91771 | |
dc.identifier.uri | https://app.trdizin.gov.tr/makale/TXpZNE1EQTRPQT09 | |
dc.identifier.uri | https://hdl.handle.net/11436/5735 | |
dc.description.abstract | Objective: Despite recommendations from heart failure guidelines on the use of pharmacologic and device therapy in patients with heart failure with reduced ejection fraction (HFrEF), important inconsistencies in guideline adherence persist in practice. The aim of this study was to assess ad-herence to guideline-directed medical and device therapy for the treatment of patients with chronic HFrEF (left ventricular ejection fraction ?40%).Methods: The Adherence to guideline-directed medical and device Therapy in outpAtients with HFrEF (ATA) study is a prospective, multicenter, observational study conducted in 24 centers from January 2019 to June 2019.Results: The study included 1462 outpatients (male: 70.1%, mean age: 67±11 years, mean LVEF: 30%±6%) with chronic HFrEF. Renin–angiotensin system (RAS) inhibitors, beta-blockers, mineralocorticoid receptor antagonists (MRAs), and ivabradin were used in 78.2%, 90.2%, 55.4%, and 12.1% of patients, respectively. The proportion of patients receiving target doses of medical treatments was 24.6% for RAS inhibitors, 9.9% for beta-blockers, and 10.5% for MRAs. Among patients who met the criteria for implantable cardioverter–defibrillator (ICD) and cardiac resynchro-nization therapy (CRT), only 16.9% of patients received an ICD (167 of 983) and 34% (95 of 279) of patients underwent CRT (95 of 279).Conclusion: The ATA study shows that most HFrEF outpatients receive RAS inhibitors and beta-blockers but not MRAs or ivabradin when the medical reasons for nonuse, such as drug intolerance or contraindications, are taken into account. In addition, most eligible patients with HFrEF do not receive target doses of pharmacological treatments or guideline-recommended device therapy. (Anatol J Cardiol 2020; 24: 32-40) | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Adherence | en_US |
dc.subject | Chronic Heart Failure | en_US |
dc.subject | Device Therapy | en_US |
dc.subject | Guidelines | en_US |
dc.subject | Pharmacological Treatment | en_US |
dc.subject | Outpatients | en_US |
dc.title | Adherence to guideline-directed medical and device Therapy in outpAtients with heart failure with reduced ejection fraction: the ATA study | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Kınık, Mustafa | |
dc.identifier.doi | 10.14744/AnatolJCardiol.2020.91771 | |
dc.identifier.volume | 24 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.startpage | 32 | en_US |
dc.identifier.endpage | 40 | en_US |
dc.ri.edit | oa | en_US |
dc.relation.journal | The Anatolian Journal of Cardiology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |