Ara
Toplam kayıt 66, listelenen: 51-60
An investigation of the protective effect of rhododendron luteum extract on cisplatin-induced DNA damage and nephrotoxicity and biochemical parameters in rats
(University of Agriculture, 2023)
The nephrotoxicity mechanisms caused by cisplatin (CP), which is used in the treatment of different types of cancer, include several processes, such as DNA damage, apoptosis, inflammation, and oxidative stress. This study ...
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
(Karger, 2023)
Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ...
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
(Wiley, 2024)
Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ...
Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
(Elsevier, 2023)
Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although cisplatin (CP) is widely
used in chemotherapy, its toxicity in healthy tissues, including ovotoxicity, is an insurmountable problem. ...
N-acetylcysteine ameliorates 5-fluorouracil-induced ovarian injury in rats
(Marmara Üniversitesi, 2023)
Objective: Although 5-fluorouracil (5-FU) is one of the most commonly used chemotherapeutics worldwide, it has been shown that 5-FU administration can cause reproductive toxicity in recent years. N-acetylcysteine (NAC) is ...
Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway
(Elsevier, 2023)
Reproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. Here, we aimed to determine therapeutic effect of GTA against ...
Melatonin supports nonsurgical periodontal treatment in patients with Type 2 diabetes mellitus and periodontitis: A randomized clinical trial
(Wiley, 2023)
Background: Diabetes mellitus (DM)-associated hyperinflammatory host response significantly provokes periodontal tissue destruction. In this context, the support of nonsurgical periodontal therapy in diabetics with host ...
Dietary acrylamide exposure and health risk assessment of pregnant women: A case study from Türkiye
(Wiley, 2023)
This study aimed to determine the acrylamide exposure of pregnant women resulting from the consumption of bread, coffee, and French fries and to evaluate it in terms of carcinogenic and non-carcinogenic health risks. ...
The impact of apelin-13 on cisplatin-induced endocrine pancreas damage in rats: an in vivo study
(Springer, 2024)
Apelin-13 is a peptide hormone that regulates pancreatic endocrine functions, and its benefits on the endocrine pancreas are of interest. This study aims to investigate the potential protective effects of apelin-13 in ...
Karbapeneme dirençli acinetobacter baumannii klinik izolatlarının moleküler epidemiyoloji açısından araştırılmasında üç farklı yöntemin karşılaştırılması
(2024)
Bu çalışmada, karbapenem dirençli oksasilinaz tipi karbapenemaz genlerini taşıyan Acinetobacter baumannii izolatlarının “uluslararası yüksek riskli klonlar” (IC I, II ve III) ile ilişkisinin farklı moleküler epidemiyolojik ...