Güncel Gönderiler: Sağlık Hizmetleri Meslek Yüksekokulu Koleksiyonu
Toplam kayıt 84, listelenen: 21-40
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The effect of interleukin-20 on periodontal tissue destruction in individuals with periodontitis
(Wiley, 2024)Background and ObjectivePeriodontitis is an inflammatory disease that destroys periodontal tissues. Interleukin-20 (IL-20), on the other hand, is known as a potent angiogenic, chemotactic, and pro-inflammatory cytokine ... -
N-acetylcysteine ameliorates 5-fluorouracil-induced ovarian injury in rats
(Marmara Üniversitesi, 2023)Objective: Although 5-fluorouracil (5-FU) is one of the most commonly used chemotherapeutics worldwide, it has been shown that 5-FU administration can cause reproductive toxicity in recent years. N-acetylcysteine (NAC) is ... -
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
(Wiley, 2024)Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ... -
Melatonin supports nonsurgical periodontal treatment in patients with Type 2 diabetes mellitus and periodontitis: A randomized clinical trial
(Wiley, 2023)Background: Diabetes mellitus (DM)-associated hyperinflammatory host response significantly provokes periodontal tissue destruction. In this context, the support of nonsurgical periodontal therapy in diabetics with host ... -
Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
(Elsevier, 2023)Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although cisplatin (CP) is widely used in chemotherapy, its toxicity in healthy tissues, including ovotoxicity, is an insurmountable problem. ... -
Dietary acrylamide exposure and health risk assessment of pregnant women: A case study from Türkiye
(Wiley, 2023)This study aimed to determine the acrylamide exposure of pregnant women resulting from the consumption of bread, coffee, and French fries and to evaluate it in terms of carcinogenic and non-carcinogenic health risks. ... -
Gentisic acid ameliorates cisplatin-induced reprotoxicity through suppressing endoplasmic reticulum stress and upregulating Nrf2 pathway
(Elsevier, 2023)Reproductive toxicity is a serious side effect of cisplatin (CP) chemotherapy. Gentisic acid (GTA) is a phenolic acid with strong antioxidant properties. Here, we aimed to determine therapeutic effect of GTA against ... -
An investigation of the protective effect of rhododendron luteum extract on cisplatin-induced DNA damage and nephrotoxicity and biochemical parameters in rats
(University of Agriculture, 2023)The nephrotoxicity mechanisms caused by cisplatin (CP), which is used in the treatment of different types of cancer, include several processes, such as DNA damage, apoptosis, inflammation, and oxidative stress. This study ... -
Alpha-pinene neutralizes cisplatin-induced reproductive toxicity in male rats through activation of Nrf2 pathway
(Springer, 2023)Purpose Testicular toxicity is one of the most important side efects of cisplatin (CP) therapy. Alpha-pinene (AP) is a naturally occurring monoterpene with antioxidant character in plants. Here, we aimed to evaluate the ... -
COVID-19 vaccine acceptance, trust in vaccine, anxiety levels, and related factors in Turkish society
(Cambridge University Press, 2023)Background: Vaccine acceptance and trust in vaccines pose a complex process affected by many factors. The present study was conducted to determine coronavirus disease 2019 (COVID-19) vaccine acceptance, trust in vaccines, ... -
Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
COVID-19’un psikolojik etkisi ve kendini toparlama
(Gümüşhane Üniversitesi, 2023)Bu araştırma COVID-19 tanısı alan bireylerin yaşadıkları psikolojik semptomları ve kendilerini toparlama düzeylerini belirlemek amacıyla yapıldı. Tanımlayıcı-kesitsel tipte yapılan bu araştırmanın örneklemini Haziran ... -
Hemşirelerde koronafobi ve kendini toparlama gücü arasındaki ilişki
(Sağlık ve Sosyal Yardım Vakfı, 2023)Amaç: Bu araştırmanın amacı COVID-19 pandemi döneminde hemşirelerin yaşadıkları koronafobi ve kendilerini toparlama düzeylerini etkileyen faktörleri ve aralarındaki ilişkiyi belirlemektir. Gereç ve Yöntem: Tanımlayıcı ve ... -
The ameliorative effect of Primula vulgaris on cisplatin-induced nephrotoxicity in rats and quantification of its phenolic components using LC-ESI-MS/MS
(Elsevier, 2023)Cisplatin (CDDP) is an important chemotherapeutic agent, accumulation of which in kidney tissue causes nephrotoxicity and renal failure. The aim of this study was to evaluate, for the first time in the literature, the ... -
Protective effect of vaccinium myrtillus extract on x-ray irradiation-induced retinal toxicity via enos and 8-ohdgexpression
(Karger, 2023)Every year, hundreds of thousands of cancer patients receive radiotherapy treatment. Oxidative stress is observed in healthy tissues due to irradiation exposure. The present study is the first to address the effects of ... -
Arbutin abrogates testicular ischemia/reperfusion injury in rats through repression of inflammation and ER stress
(Elsevier, 2023)The aim of this study was to investigate the effects of arbutin (ARB) administration on oxidative stress, inflammation, endoplasmic reticulum (ER) stress and apoptosis in an experimental testicular torsion/detorsion ... -
Syringic acid ameliorates ischemia/reperfusion-induced testicular injury in rats via suppressing of HMGB1/NF-kappa B axis and endoplasmic reticulum stress
(Springer, 2023)PurposeTo investigate the possible protective role of syringic acid on torsion/detorsion-induced testicular injury using biochemical and histopathological approaches for the first time.MethodsA total of 24 rats were divided ... -
Ethyl pyruvate attenuates cisplatin-induced ovarian injury in rats via activating Nrf2 pathway
(Taylor & Francis Ltd., 2023)Although cisplatin (CDDP) is an antineoplastic drug widely used for the treatment of various tumors, its toxicity on the reproductive system is a concern for patients. Ethyl pyruvate (EP) possesses potent antioxidant and ... -
The therapeutic effect of silibinin against 5-fluorouracil-induced ovarian toxicity in rats
(Wiley, 2023)5-Fluorouracil (5-FU) is a fluoropyrimidine group antineoplastic drug with antimetabolite properties and ovotoxicity is one of the most important side effects. Silibinin (SLB) is a natural compound that is used worldwide ... -
Chlorogenic acid attenuates cisplatin-induced ovarian injury in rats
(Taylor & Francis Ltd., 2023)The aim of this study was to determine the possible therapeutic effect of chlorogenic acid (CGA) on cisplatin (CDDP)-induced ovarian damage in rats. Rats were first exposed to CDDP (5 mg/kg) and then treated CGA (1.5 and ...
