Bilateral pseudoaneurysm secondary to intraarterial tianeptine abuse

Abstract

Mycotic aneurysms occur due to destruction of the vessel wall, either by infection of a previously healthy artery wall, or through secondary infection of a preexisting aneurysm. Although mycotic aneurysms are frequent in femoral artery, mycotic pseudoaneurysms of femoral artery are rare (1, 2). Tianeptine is a tricyclic antidepressant with a unique mechanism of action as a glutamatergic modulator. However, tianeptine is also known for its abuse and dependence potential (3-5). We hereby report a case with bilateral femoral pseudoaneurysm due to intraarterial administration of tianeptine in a patient with drug addiction, and surgical treatment of this type of pseudoaneurysm.