Ara
Toplam kayıt 67, listelenen: 61-67
The potential antioxidant effect of N-acetylcysteine on X-ray ionizing radiation-induced pancreas islet cell toxicity
(Elsevier, 2023)
Purpose
Previous research has highlighted the impact of X-ray irradiation-induced organ damage, on cancer patients after radiation therapy. The ionizing radiation-induced oxidative stress causes injury to the pancreatic ...
Preventive effects of melatonin on periodontal tissue destruction due to psychological stress in rats with experimentally induced periodontitis
(Wiley, 2024)
Objective and Background: Psychological stress is a potential modifiable environmental risk factor causally related to the exacerbation of periodontitis and other chronic inflammatory diseases. This animal study aimed to ...
Evaluation of the therapeutic effects of arbutin on cisplatin-induced ovarian toxicity in rats through endoplasmic reticulum stress and Nrf2 pathway
(Elsevier, 2023)
Arbutin (ARB) is a glycosylated hydroquinone with potent antioxidant effects. Although cisplatin (CP) is widely
used in chemotherapy, its toxicity in healthy tissues, including ovotoxicity, is an insurmountable problem. ...
N-acetylcysteine ameliorates 5-fluorouracil-induced ovarian injury in rats
(Marmara Üniversitesi, 2023)
Objective: Although 5-fluorouracil (5-FU) is one of the most commonly used chemotherapeutics worldwide, it has been shown that 5-FU administration can cause reproductive toxicity in recent years. N-acetylcysteine (NAC) is ...
Evaluation of the protective effect of coenzyme Q10 against x-ray irradiation-induced ovarian injury
(Wiley, 2024)
Aim: This study focused on the anti-oxidant and anti-apoptotic effects of CoQ10 in ovaries exposed to pelvic radiation. Methods: Thirty-two female rats were randomly assigned into four groups. Group I (control group), Group ...
Arbutin abrogates cisplatin-induced hepatotoxicity via upregulating Nrf2/HO-1 and suppressing genotoxicity, NF-κB/iNOS/TNF-α and caspase-3/Bax/Bcl2 signaling pathways in rats
(Oxford University Press, 2024)
Background: Cisplatin is a potent anticancer agent widely employed in chemotherapy. However, cisplatin leads to toxicity on non-targeted healthy organs, including the liver. We investigated the hepatoprotective mechanism ...
Gallic acid attenuates torsion/detorsion-induced testicular injury in rats through suppressing of HMGB1/NF- κB axis and endoplasmic reticulum stress
(Elsevier, 2024)
It was aimed to evaluate whether gallic acid (GA) have a beneficial effect in the testicular ischemia/reperfusion injury (IRI) model in rats for the first time. Testicular malondialdehyde, 8-hydroxy-2 '-deoxyguanosine, ...