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Toplam kayıt 79, listelenen: 41-50
Effects of infliximab against methotrexate toxicity in splenic tissue via the regulation of CD3, CD68, and C200R in rats
(Karger, 2018)
Methotrexate (MTX), which has been used in clinical practice for approximately 70 years, is still widely employed in the treatment of rheumatoid arthritis (RA), psoriasis, and cancer. Although MTX toxicity causes nephrotoxicity, ...
Changes in testicular morphology and oxidative stress biomarkers in 60-day-old Sprague Dawley rats following exposure to continuous 900-MHz electromagnetic field for 1 h a day throughout adolescence
(Pergamon-Elsevier Science Ltd, 2018)
The purpose of this study was to investigate the 60-day-old male rat testis following exposure to continuous 900-megahertz (MHz) electromagnetic field (EMF) throughout the adolescent period using histopathological and ...
The protective effect of astaxanthin against cisplatin-induced nephrotoxicity in rats
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2018)
Purpose: the aim of this experimental study was to investigate the antioxidant effects of astaxanthin against cisplatin-induced nephrotoxicity in rats. Methods: Forty-eight male Sprague-Dawley rats weighing 264.83 +/- 7.39 ...
An investigation of the effects of metformin on ovarian ischemia-reperfusion injury in rats
(Elsevier, 2019)
Damage to the ovaries or tissue torsion can significantly reduce the ovarian reserve and thus cause severe gynecological and hormonal deficiencies. the discovery of new agents is always needed in the treatment of this ...
Effects of infliximab against carbon tetrachloride-induced intestinal injury via lipid peroxidation and apoptosis
(Sage Publications Ltd, 2019)
Carbon tetrachloride (CCL4) is often employed in the production of chlorofluorocarbons, petroleum refining, oil and rubber processing, and laboratory applications. Oral, subcutaneous, and inhalation exposure to CCL4 in ...
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats
(Taylor & Francis Ltd, 2019)
Purpose: We investigated the radioprotective effect of endogenous melatonin release at different times associated with the circadian rhythm on head and neck radiotherapy. Materials and methods: Two groups of animals were ...
The radioprotective effect of N-acetylcysteine against x-radiation-induced renal injury in rats
(Springer Heidelberg, 2019)
The purpose of this study was therefore to investigate the effects of radiotherapy on the kidney and the potential use of agents such as N-acetylcysteine (NAC) in developing a future therapeutic protocol for radiation-induced ...
Protective effect of whortleberry extract on salivary gland damage induced by neck irradiation in rats
(Sage Publications Inc, 2019)
Radiotherapy is a method of treatment used on malignant head and neck tumors; however, it may lead to adverse effects by influencing other tissues because its effects are not specific to tumor tissues. These adverse effects ...
An investigation of the effects of N-acetylcysteine on radiotherapy-induced testicular injury in rats
(Springer, 2019)
According to data issued by the International Agency for Research on Cancer in 2012, the estimated number of new cases of all types of cancer worldwide was estimated to exceed 10 million, and 6 million of whom receive ...
The protective effects of astaxanthin against cisplatin-induced retinal toxicity
(Taylor & Francis Ltd, 2019)
Purpose: This study investigated the toxic effects of an antineoplastic agent, cisplatin (CIS), on retinal cells and the potential capacity of astaxanthin (ASTA) to elicit a future therapeutic protocol in CIS-induced retinal ...