dc.contributor.author | Çerçi, Pamir | |
dc.contributor.author | Kendirlinan, Reşat | |
dc.contributor.author | Büyüköztürk, Suna | |
dc.contributor.author | Gelincik, Aslı | |
dc.contributor.author | Ünal, Derya | |
dc.contributor.author | Demir, Semra | |
dc.contributor.author | Erkekol, Ferda Öner | |
dc.contributor.author | Karakaya, Gül | |
dc.contributor.author | Dursun, Adile Berna | |
dc.contributor.author | Çelikel, Serhat | |
dc.contributor.author | Ediger, Dane | |
dc.contributor.author | Abadoğlu, Öznur | |
dc.contributor.author | Bavbek, Sevim | |
dc.date.accessioned | 2023-10-25T05:45:43Z | |
dc.date.available | 2023-10-25T05:45:43Z | |
dc.date.issued | 2023Allergologia et immunopathologia | en_US |
dc.identifier.citation | Çerçi, P., Kendirlinan, R., Büyüköztürk, S., Gelincik, A., Ünal, D., Demir, S., Erkekol, F. Ö., Karakaya, G., Dursun, A. B., Çelikel, S., Ediger, D., Abadoglu, O., & Bavbek, S. (2023). Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs in adults: Beyond current classification. Allergologia et immunopathologia, 51(5), 84–92. https://doi.org/10.15586/aei.v51i5.946 | en_US |
dc.identifier.issn | 0301-0546 | |
dc.identifier.issn | 1578-1267 | |
dc.identifier.issn | 0301-0546 | |
dc.identifier.uri | https://doi.org/10.15586/aei.v51i5.946 | |
dc.identifier.uri | https://hdl.handle.net/11436/8570 | |
dc.description.abstract | Background: Hypersensitivity reactions (HSRs) to nonsteroidal anti-inflammatory drugs (NSAIDs)
are a significant clinical issue. Several classifications have been proposed to categorize these
reactions, including the current European Academy of Allergy and Clinical Immunology/
European Network for Drug Allergy (EAACI/ENDA) classification. This study aimed to evaluate
the applicability of this classification in a real-world clinical setting.
Methods: We conducted a national multicenter study involving patients from nine hospitals in
four major urban centers in Turkey. All patients had a suggestive clinical history of hypersensitivity reactions to NSAIDs. Researchers collected data using a structured form and classified
reactions based on the EAACI/ENDA classification. Oral provocation tests with several NSAIDs
were performed using a single-blind challenge per EAACI/ENDA guidelines.
Results: Our retrospective study included 966 adult patients with a history of hypersensitivity
to NSAIDs. The most common triggers were Acetylsalicylic Acid (ASA), paracetamol, and metamizole. The most prevalent acute NSAID hypersensitivity group was NSAID-induced urticaria/ | en_US |
dc.language.iso | eng | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Adverse drug | en_US |
dc.subject | Reactions | en_US |
dc.subject | Classification | en_US |
dc.subject | Hypersensitivity | en_US |
dc.subject | NSAIDs | en_US |
dc.subject | Phenotyping | en_US |
dc.title | Hypersensitivity reactions to nonsteroidal anti-inflammatory drugs in adults: Beyond current classification | en_US |
dc.type | article | en_US |
dc.contributor.department | RTEÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.contributor.institutionauthor | Dursun, Adile Berna | |
dc.identifier.doi | 10.15586/aei.v51i5.946 | en_US |
dc.identifier.volume | 51 | en_US |
dc.identifier.issue | 5 | en_US |
dc.identifier.startpage | 84 | en_US |
dc.identifier.endpage | 92 | en_US |
dc.relation.journal | Allergologia et Immunopathologia | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |