Kurum Yazarı "Tümkaya, Levent" Scopus İndeksli Yayınlar Koleksiyonu İçin Listeleme
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The role of vaccinium myrtillus in the prevention of renal injury in an experimental model of ruptured abdominal aortic aneurysm
Ergene, Şaban; Hemşinli, Doğuş; Karakişi, Sedat Ozan; Mercantepe, Tolga; Tümkaya, Levent; Yılmaz, Adnan (Soc Brasil Cirurgia Cardiovasc, 2020)Objective: To examine the biochemical and histopathological renal effects of ischemia/reperfusion (I/R) injury using a ruptured abdominal aortic aneurysm (RAAA) model in rats and to investigate the potential protective ... -
Tea grape reduces abdominal aortic occlusion-induced lung injury
Hemşinli, Doğuş; Ergene, Şaban; Karakişi, Sedat Ozan; Mercantepe, Tolga; Tümkaya, Levent; Yılmaz, Adnan; Akyıldız, Kerimali (Soc Brasil Cirurgia Cardiovasc, 2020)Introduction: Ischemia-associated mortality caused by aortic cross-clamps, as in ruptured abdominal aorta aneurysm surgeries, and reperfusion following their removal represent some of the main emergency conditions in ... -
The therapeutic effect of thymoquinone on acoustic trauma-induced hearing loss in rats
Oğurlu, Mahmut; Erdivanlı, Özlem Çelebi; Tümkaya, Levent; Özgür, Abdulkadir; Coşkun, Zerrin Özergin; Terzi, Suat; Demirci, Münir; Dursun, Engin (Springer, 2017)Thymoquinone has antioxidant properties. We hypothesized that thymoquinone may prevent or alleviate hearing loss induced by acoustic trauma. We aimed to study thymoquinone's effect on hearing function with distortion-product ... -
Topiramate ameliorates abdominal aorta cross-clamping induced liver injury in rats
Cüre, Erkan; Cüre, Medine Cumhur; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İbrahim; Kırbaş, Aynur; Yılmaz, Arif; Yüce, Süleyman; Gökçe, Mehmet Fatih (Wolters Kluwer Medknow Publications, 2014)Background and Aim: Ischemia/reperfusion (I/R) injury in the liver occurs after a prolonged period of ischemia followed by restoration of hepatic blood perfusion. During the surgery of abdominal aorta, I/R injury causes ... -
Topiramate has protective effect on renal injury
Cüre, Medine Cumhur; Cüre, Erkan; Tümkaya, Levent; Kalkan, Yıldıray; Aydın, İlkyaz; Kırbaş, Aynur; Efe, Hasan; Şehitoğlu, İbrahim; Yüce, Süleyman (Comenius Univ, 2015)Background: Topiramate (TPM) decreases tumor necrosis factor-alpha (TNF-alpha) and oxidative stress. We investigated protective effects of TPM on cell damage in kidney tissue during ischemia-reperfusion (I/R) damage. ... -
Topiramate reduces aortic cross-clamping-induced lung injury in male rats
Kurt, Aysel; Kalkan, Yıldıray; Türüt, Hasan; Cüre, Medine Cumhur; Tümkaya, Levent; Cüre, Erkan (NLM (Medline), 2018)BACKGROUND: Topiramate (TPM) decreases cytokine release and generation of reactive oxygen species (ROS). Cytokine and endothelin-1 (ET-1) secretion and ROS formation play an important role in ischemia-reperfusion (I/R) ... -
Toward changing of the pathophysiologic Basis of Acute Hydrocephalus after subarachnoid hemorrhage: a preliminary experimental study
Kanat, Ayhan; Türkmenoğlu, Osman; Aydın, Mehmet D.; Yolşs, Coşkun; Aydın, Nazan; Gürsan, Nesrin; Tümkaya, Levent; Demir, Recep (Elsevier Science Inc, 2013)BACKGROUND: Acute hydrocephalus (ventricular enlargement within 72 hours) is a common complication in patients with aneurysmal subarachnoid hemorrhage (SAH). Cerebrospinal fluid (CSF) secretion may be increased in the early ... -
White tea reduced bone loss by suppressing the TRAP/CTX pathway in ovariectomy-induced osteoporosis model rats
Yıldırım, Murat; Saral, Sinan; Mercantepe, Tolga; İskender, Hatice; Tümkaya, Levent; Atak, Mehtap; Taşçı, Filiz (S. Karger AG, 2020)Osteoporosis is an important skeletal disease characterized by bone weakness and high risk of fracture in postmenopausal women. Tea consumption is known to play an important role in the prevention or alleviation of ... -
Whortleberry protects kidney against the cisplatin-induced nephrotoxicity: an experimental study
Eren, Hüseyin; Aydın, Hasan Rıza; Tümkaya, Levent; Kazaz, İlke Onur; Kalkan, Yıldıray; Kazaz, Seher Nazlı; Mercantepe, Tolga; Horsanali, Mustafa Ozan; Yılmaz, Adnan (Taylor & Francis Ltd, 2018)Purpose: This study investigated the antioxidant effects of whortleberry against cisplatin-induced nephrotoxicity in rats.Material and methods: This study included 48 female Sprague-Dawley rats weighing 263.688.29g. the ... -
Zoledronic acid aggravates kidney damage during ischemia reperfusion injury in rat
Şehitoğlu, İbrahim; Tümkaya, Levent; Bedir, Recep; Kalkan, Yıldıray; Cüre, Medine Cumhur; Yücel, Ahmet Fikret; Zorba, Orhan Ünal; Yüce, Süleyman; Cüre, Erkan (Begell House Inc., 2015)Introduction: Zoledronic acid (ZA), a bisphosphonate, increases the levels of cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-?), and reactive oxygen species (ROS) in subjects without cancer. ...