Yazar "RTEÜ, Mühendislik ve Mimarlık Fakültesi, Biyomühendislik Bölümü" için Scopus İndeksli Yayınlar Koleksiyonu listeleme
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Identification of novel inhibitors of the ABC transporter BmrA
Serçinoğlu, Onur; Şentürk, Duygu; Altınışık Kaya, Fatma Ece; Avcı, Fatma Gizem; Frlan, Rok; Tomašič, Tihomir; Özbek, Pemra; Orelle, Cédric; Jault, Jean-Michel; Sarıyar Akbulut, Berna (Academic Press Inc., 2020)The resistance of microbes to commonly used antibiotics has become a worldwide health problem. A major underlying mechanism of microbial antibiotic resistance is the export of drugs from bacterial cells. Drug efflux is ... -
In silico studies to develop new GSK3β inhibitors effective in the alzheimer's disease
Yalçın Özkat, Gözde; Yıldız, İlkay (Bentham Science Publishers, 2022)Background: Alzheimer's disease affects a large part of the world’s population by prolonging the human life span and becoming an economic burden in the health system. Therefore, its treatment be-comes more and more important ... -
Mentha longifolia ssp. longifolia essential oil components as novel carbonic anhydrase isoform II and IX inhibitors: biological and molecular docking studies
Karaçelik, Ayça Aktaç; Özkat, Gözde Yalçın (Bentham Science Publications, 2023)Background: Medicinal plant oils are used in the treatment of various human diseases due to their phytochemical components. Recently, enzyme inhibition studies have been increasing in cosmetics, the food industry, and ... -
Molecular modeling strategies of cancer multidrug resistance
Yalçın Özkat, Gözde (Elsevier, 2021)Cancer remains a leading cause of morbidity and mortality worldwide. Hence, the increase in cancer cases observed in the elderly population, as well as in children and adolescents, makes human malignancies a prime target ... -
MoS2/Chitosan/GOx-Gelatin modified graphite surface: Preparation, characterization and its use for glucose determination
Altuntaş, Derya Bal; Kuralay, Filiz (Elsevier, 2021)Graphene-like new generation of two dimensional (2D) nanomaterials, in particular the family of transition metal dichalcogenides (TMDCs) have been attracting a wide range of research interest. Among the family of TMDCs, ... -
Plant biomass: insights from imaging cell walls using molecular probes
Avcı, Utku (2016)Cell walls are an important and growing subject of research in plant biology. In the last decade, there has been an increasing interest in using cell walls as feedstock for the production of second generation biofuels. ... -
ProSNEx: a web-based application for exploration and analysis of protein structures using network formalism
Aydınkal, Rasim Murat; Serçinoğlu, Onur; Özbek, Pemra (Oxford Univ Press, 2019)ProSNEx (Protein Structure Network Explorer) is a web service for construction and analysis of Protein Structure Networks (PSNs) alongside amino acid flexibility, sequence conservation and annotation features. ProSNEx ... -
Sequence-structure-function relationships in class I MHC: A local frustration perspective
Serçinoğlu, Onur; Özbek, Pemra (Public Library Science, 2020)Class I Major Histocompatibility Complex (MHC) binds short antigenic peptides with the help of Peptide Loading Complex (PLC), and presents them to T-cell Receptors (TCRs) of cytotoxic T-cells and Killer-cell Immunglobulin-like ... -
Spectroscopic, quantum mechanical studies, ligand protein interactions and photovoltaic efficiency modeling of some bioactive benzothiazolinone acetamide analogs
Mary, Y. Sheena; Yalçın, Gözde; Mary, Y. Shyma; Resmi, K. S.; Thomas, Renjith; Onkol, Tijen; Kasap, Esin Nagihan (Springer International Publishing Ag, 2020)In the present work, the molecules, N-(4-chlorophenyl)-2-[6-(benzoyl)-2-benzothiazolinone-3-yl]acetamide (CBBA), N-(6-methyl-2-pyridyl)-2-[6-(2-chlorobenzoyl)-2-benzothiazolinone-3-yl]acetamide (MCBA), N-(3-Chlorophenyl) ... -
Syntheses, crystal structures, hirshfeld surface analyses and electrochemical etoposide/camptotechin sensor applications of acetaldehyde oxime derivatives
Topkaya, Cansu; Aslan, Sema; Hökelek, Tuncer; Göktürk, Tolga; Kıncal, Sultan; Güp, Ramazan; Bal Altuntaş, Derya (Elsevier, 2022)(E)-2-(4-Hydroxyphenyl)-2-oxoacetaldehyde oxime monohydrate (I) and (E)-2-(4 Nitropheny1)-2oxoacetaldehyde oximes (II) were synthesized from 4'-hydroxyacetophenone and 4'-nitroacetophenone, respectively. Their structures ... -
Synthesis and characterization of activated carbon produced from waste human hair mass using chemical activation
Bal Altuntaş, Derya; Nevruzoğlu, Vagif; Dokumacı, Meryem; Cam, Şafak (Springer Japan Kk, 2020)In this study, hair waste was converted into active carbon for the first time and its characteristics were analyzed. As chemical activation tool, zinc chloride (ZnCl2) was impregnated and then carbonized under different ... -
Synthesis and molecular docking studies of some novel antimicrobial benzamides
Acar, Cemre; Yalçın Özkat, Gözde; Ertan-Bolelli, Tuğba; Onurdağ, Fatma Kaynak; Ökten, Suzan; Şener, Funda; Yıldız, İlkay (Academic Press Inc Elsevier Science, 2020)Common use of classical antibiotics has caused to the growing emergence of many resistant strains of pathogenic bacteria. Therefore, we aimed to synthesize a number of N-(2-hydroxy-(4 or 5)-nitrophenyl)benzamide derivatives ... -
Synthesis of new carbon material produced from human hair and its evaluation as electrochemical supercapacitor
Altuntaş, Derya Bal; Aslan, Sema; Akyol, Yeşim; Nevruzoğlu, Vagif (Taylor & Francis Inc, 2020)In this study, carbon material similar to graphene structure (GLS) was prepared from graphite and the carbonization of Turkish human hair fibers (HHC) and utilized for the modification of electrode to evaluate the ... -
Synthesis, biological activities, antioxidant properties, and molecular docking studies of novel bis-schiff base podands as responsive chemosensors for anions
Yapar, Gönül; Demir, Neslihan; Kiraz, Aşkın; Yalçın Özkat, Gözde; Yıldız, Mustafa (Elsevier, 2022)In this study, bis-carbonyl podand (triethylene glycol bis(2-carbonylphenyl)ether) ( 1 ) was synthesized from the reaction of triethylene glycol dichloride with salicylaldehyde. Then, Schiff base podans ( 2 and 3 ) were ... -
Synthesis, molecular docking and some metabolic enzyme inhibition properties of biphenyl-substituted chalcone derivatives
Burmaoğlu, Serdar; Kazancıoğlu, Elif Akın; Kazancıoğlu, Mustafa Z.; Sağlamtaş, Rüya; Yalçın Özkat, Gözde; Gülçin, İlhami; Algül, Öztekin (Elsevier, 2022)The new synthesized biphenyl-substituted chalcone derivatives were evaluated against the human carbonic anhydrase isoenzymes I and II (hCA I and hCA II), acetylcholinesterase (AChE), and butyrylcholinesterase (BChE) enzymes. ...