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Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
(Sage Publications Inc, 2015)
Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ...
Reversal of rocuronium-induced neuromuscular block with sugammadex and resulting histopathological effects in rat kidneys
(Taylor & Francis, 2011)
Background: This study investigated the effect of injection of rocuronium or sugammadex alone and rocuronium + sugammadex on urea, creatinine, electrolyte levels, and histopathological findings in rats. Methods: Thirty-six ...
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells
(Springer Link, 2012)
Purpose: Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of ...
Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study
(Springer, 2012)
Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ...