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Toplam kayıt 9, listelenen: 1-9
Microwave assisted synthesis of some hybrid molecules derived from norfloxacin and investigation of their biological activities
(Elsevier France-Editions Scientifiques Medicales Elsevier, 2013)
Norfloxacin was converted to 7-(4-amino-2-fluorophenyl)piperazin derivative (2) via the formation of nitro compound. the synthesis of the norfloxacin derivatives containing 1,3-thiazole or 1,3-thiazolidin moiety was performed ...
Novel microwave assisted synthesis and antimicrobial activity of new quinolone-hybrids
(Bentham Science Publ Ltd, 2016)
Background: Carbo(thio)amid derivatives 4a, 4b were obtained starting from nalidixic acid in three steps. the acidic treatment of compound 4a generated the corresponding 1,3,4-oxadiazole (5), while the compound 4a gave ...
Synthesis of novel antipyrine-azole-S-alkyl derivatives antimicrobial activity, molecular docking, and computational studies
(Elsevier, 2022)
In this investigation, we synthesized the newly antipyrine-azole-S-alkyl and their reduction derivatives that were screened for their antimicrobial activity and compared them with molecular docking and computational Studies. ...
Novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) hybrid compounds: Design, synthesis, efficient antibacterial activity and antioxidant effects
(Academic Press Inc Elsevier Science, 2019)
In this study, novel imidazo[2,1-b] [1,3,4]thiadiazole (ITD) compounds were synthesized and their antimicrobial and antioxidant capacity was examined. the C-2 position of the ITD structure was fixed with the 3,4-hydroxybenzene ...
Synthesis of novel antipyrine derivatives possessing remarkable antimicrobial activities
(Wiley-V C H Verlag Gmbh, 2019)
In this study, new triazole, thiazole, oxazole and Mannich bases were synthesized starting from antipyrine. All the newly synthesized compounds were screened for their antimicrobial activities against some test microorganisms ...
Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities
(Elsevier, 2009)
4-Phenyl-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (3) was obtained in basic media via the formation of 2-isonicotinoyl-N-phenylhydrazinecarbothioamide (2), and converted to some alkylated derivatives (4a,b) and Mannich ...
Synthesis of some new 1,2,4-triazoles starting from isonicotinic acid hydrazide and evaluation of their antimicrobial activities
(Elsevier, 2009)
5-Pyridin-4-yl-1,3,4-oxadiazole-2-thiol (2) was obtained from the reaction of isonicotinic acid hydrazide with carbon disulfide in basic media and converted into 4-amino-5-pyridin-4-yl-4H-1,2,4-triazole-3-thiol (5) by the ...
Cyclization of some carbothioamide derivatives containing antipyrine and triazole moieties and investigation of their antimicrobial activities
(Elsevier, 2010)
Acetohydrazide derivative containing both antipyrine and triazole nuclei (5) was obtained starting from ethyl hydrazinecarboxylate derivative (2) and 4-aminoantipyrine (1) by three steps. The treatment of compound 5 with ...
Design and synthesis of some azole derivatives as potential antimicrobial agents
(Birkhauser Boston, 2012)
Syntheses of 1,2,4-triazol-3-ones, 4a, 4b, and 5 were performed starting from ester ethoxycarbonylhyd-razones (1a, 1b) that were reported earlier. The treatment of triazole derivatives, 4a, 4b, and 5 with several sulfonyl ...