Yazar "Tümkaya, Levent" için PubMed İndeksli Yayınlar Koleksiyonu listeleme
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The effect of prenatal exposure to 1800 MHz electromagnetic field on calcineurin and bone development in rats
Erkut, Adem; Tümkaya, Levent; Balık, Mehmet Sabri; Kalkan, Yıldıray; Güvercin, Yılmaz; Yılmaz, Adnan; Yüce, Süleyman; Cüre, Erkan; Şehitoğlu, İbrahim (Acta Cirurgica Brasileira, 2016)PURPOSE: To investigated the effects of exposure to an 1800 MHz electromagnetic field (EMF) on bone development during the prenatal period in rats. METHODS: Pregnant rats in the experimental group were exposed to radiation ... -
Effect of prenatal exposure to diclofenac sodium on the male rat arteries: A stereological and histopathological study
Zengin, Halit; Kaplan, Süleyman; Tümkaya, Levent; Altunkaynak, Berrin Zühal; Rağbetli, Murat Çetin; Altunkaynak, Muhammed Eyüp; Yılmaz, Özcan (Taylor & Francis Ltd., 2013)In this study, we investigated the morphometric and histological alterations of the aorta, brachial, and femoral arteries in 4- and 20-week-old rats that were prenatally exposed to diclofenac sodium (DS). For this purpose, ... -
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells
Kalkan, Yıldıray; Bostan, Habib; Tümkaya, Levent; Tomak, Yakup; Bostan, Mehmet; Yılmaz, Adnan; Türüt, Hasan; Temiz, Ahmet; Yalçın, Alper; Turan, Alparslan (Springer Link, 2012)Purpose: Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of ... -
Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
Kalkan, Yıldıray; Tümkaya, Levent; Bostan, Habib; Tomak, Yakup; Altuner, Durdu; Yılmaz, Adnan; Erdivanlı, Başar; Bedir, Recep; Yalçın, Alper; Turan, Alparslan (Sage Publications Inc, 2015)Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ... -
Effect of the prenatal electromagnetic field exposure on cochlear nucleus neurons and oligodendrocytes in rats
Tümkaya, Levent; Baş, Orhan; Mercantepe, Tolga; Çınar, Seda; Özgür, Abdulkadir; Yazıcı, Zihni Açar (Springer Heidelberg, 2022)Electromagnetic radiation from elecromagnetic field (EMF) sources has been an important health concern for a long time. The vast majority of this exposure is due to the widespread use of mobile phones, an important source ... -
Effect of white tea consumption on serum leptin, TNF-alpha and UCP1 gene expression in ovariectomized rats
Saral, Sinan; Saydam, Faruk; Dokumacıoğlu, Eda; Atak, Mehtap; Tümkaya, Levent; Uydu, Hüseyin Avni (John Libbey Eurotext Ltd., 2021)Background: Obesity and dyslipidemia due to estrogen deficiency are among the important health problems in menopausal women. Increasing evidence reports the anti-obesity and anti-hyperlipidemic properties of tea polyphenols. ... -
The effect of white tea on serum TNF-alpha/NF-kappa B and immunohistochemical parameters in cisplatin-related renal dysfunction in female rats
Saral, Sinan; Dokumacıoğlu, Eda; Mercantepe, Tolga; Atak, Mehtap; Çınar, Seda; Saral, Özlem; Yıldız, Lamiye; İskender, Hatice; Tümkaya, Levent (Elsevier France-Editions Scientifiques Medicales Elsevier, 2019)Objective: Nephrotoxicity is the most important side effect of the antineoplastic drug cisplatin, thereby restricting its use. the aim of this study was to investigate the protective effects of white tea infusions(WT) ... -
The effects of apelin-13 against cisplatin-induced nephrotoxicity in rats
Topçu, Atilla; Saral, Sinan; Mercantepe, Tolga; Akyıldız, Kerimali; Tümkaya, Levent; Yılmaz, Adnan (Taylo & Francis Ltd., 2021)Acute kidney injury (AKI) is observed in nearly 60% of patients undergoing cisplatin (CP) therapy. The aim of this study was to reveal the potential effects of apelin-13 (AP-13) in the prevention of CP-induced renal toxicity, ... -
Effects of chronic exposure to electromagnetic waves on the auditory system
Özgür, Abdulkadir; Tümkaya, Levent; Terzi, Suat; Kalkan, Yıldıray; Erdivanlı, Özlem Çelebi; Dursun, Engin (Taylor & Francis Ltd, 2015)Conclusion: the results support that chronic electromagnetic field exposure may cause damage by leading to neuronal degeneration of the auditory system. Objectives: Numerous researches have been done about the risks of ... -
The effects of curcumin on wound healing in a rat model of nasal mucosal trauma
Emiroğlu, Gökhan; Coşkun, Zerrin Özergin; Kalkan, Yıldıray; Erdivanlı, Özlem Çelebi; Tümkaya, Levent; Terzi, Suat; Özgür, Abdulkadir; Demirci, Münir; Dursun, Engin (Hindawi Ltd, 2017)We explored the effects of topical curcumin on the healing of nasal mucosal wounds. A total of 32 Sprague-Dawley Albino rats were randomized in equal numbers into four groups, and unilateral nasal wounds were created using ... -
The effects of dexmedetomidine on abdominal aortic occlusion-induced ovarian injury via oxidative stress and apoptosis
Mercantepe, Filiz; Tümkaya, Levent; Mercantepe, Tolga; Akyıldız, Kerimali; Çiftel, Serpil; Yılmaz, Adnan (Karger, 2023)Ischemia/reperfusion (IR) induced ovarian damage is caused by various diseases such as ovarian torsion, ovarian transplantation, cardiovascular surgery, sepsis, or intra-abdominal surgery. I/R-related oxidative damage can ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
The effects of dexmedetomidine on trauma-induced secondary injury in rat brain
Şen, Ahmet; Erdivanlı, Başar; Tümkaya, Levent; Uydu, Hüseyin Avni; Mercantepe, Tolga; Batçık, Şule; Özdemir, Abdullah (Taylor & Francis Ltd., 2023)Background: The objective of this study was to investigate the effect of dexmedetomidine (Dex), a sedative drug with little or no depressant effect on respiratory centers, on secondary injury in rat brain tissue by means ... -
Effects of exposure to 2100 MHz GSM-like radiofrequency electromagnetic field on auditory system of rats
Çeliker, Metin; Özgür, Abdulkadir; Tümkaya, Levent; Terzi, Suat; Yılmaz, Mustafa; Kalkan, Yıldıray; Erdoğan, Ender (Assoc Brasileira Otorrinolaringologia & Cirurgia Cervicofacial, 2017)Introduction: the use of mobile phones has become widespread in recent years. Although beneficial from the communication viewpoint, the electromagnetic fields generated by mobile phones may cause unwanted biological changes ... -
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
Çeliker, Fatma Beyazal; Tümkaya, Levent; Suzan, Zehra T.; Topçu, Atilla; Mercantepe, Tolga; Çınar, Seda; Yazıcı, Zihni Açar; Yılmaz, Adnan (Wiley, 2022)We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ... -
Effects of gadodiamide and gadoteric acid on rat kidneys: A comparative study
Çeliker, Fatma Beyazal; Tümkaya, Levent; Mercantepe, Tolga; Beyazal, Mehmet; Turan, Arzu; Beyazal Polat, Hatice; Suzan, Zehra Topal; İnecikli, Mehmet Fatih; Akyıldız, Kerimali; Yılmaz, Adnan (Wiley, 2019)Background Gadolinium-based contrast agents are complex chelates to provide contrast in NRI. However, recent studies have highlighted the deposition of free Gd+3 ion in various tissues. Purpose To evaluate the histopathological ... -
Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
Çeliker, Fatma Beyazal; Tümkaya, Levent; Yılmaz, Adnan; Coşkun, Zerrin Özergin; Çeliker, Metin; Oğhan, Fatih; Mercantepe, Tolga; Terzi, Suat; Dursun, Engin (Springer, 2018)The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ... -
Effects of gadolinium-based MRI contrast agents on liver tissue
Mercantepe, Tolga; Tümkaya, Levent; Çeliker, Fatma Beyazal; Suzan, Zehra Topal; Çınar, Seda; Akyıldız, Kerimali; Mercantepe, Filiz; Yılmaz, Adnan (Wiley, 2018)BackgroundPurposeMRI with contrast is often used clinically. However, recent studies have reported a high accumulation of gadolinium-based contrast agents (GBCAs) in kidney, liver, and spleen tissues in several mouse models. ... -
Effects of hyperbaric oxygen and iloprost on intestinal ischemia-reperfusion induced acute lung injury
Yılmaz, Yeliz; Tümkaya, Levent (Korean Surgical Society, 2019)Purpose: To research the effects of iloprost (IL) and hyperbaric oxygen (HBO) combination treatment on lung injury and on tumor necrosis factor alpha (TNF-alpha), myeloperoxidase (MPO), malondialdehyde (MDA), and soluble ... -
Effects of infliximab against carbon tetrachloride-induced intestinal injury via lipid peroxidation and apoptosis
Pergel, Ahmet; Tümkaya, Levent; Çolakoğlu, Muhammed Kadri; Demiral, Gökhan; Kalcan, Süleyman; Özdemir, Ali; Mercantepe, Tolga; Yılmaz, Adnan (Sage Publications Ltd, 2019)Carbon tetrachloride (CCL4) is often employed in the production of chlorofluorocarbons, petroleum refining, oil and rubber processing, and laboratory applications. Oral, subcutaneous, and inhalation exposure to CCL4 in ...